Gene Review:
GPR15 - G protein-coupled receptor 15
Homo sapiens
Synonyms:
BoB, Brother of Bonzo, G-protein coupled receptor 15
- CCR5, GPR15, and CXCR6 are major coreceptors of human immunodeficiency virus type 2 variants isolated from individuals with and without plasma viremia. Blaak, H., Boers, P.H., Gruters, R.A., Schuitemaker, H., van der Ende, M.E., Osterhaus, A.D. J. Virol. (2005)
- Coreceptor usage of BOB/GPR15 and Bonzo/STRL33 by primary isolates of human immunodeficiency virus type 1. Pöhlmann, S., Krumbiegel, M., Kirchhoff, F. J. Gen. Virol. (1999)
- Use of GPR1, GPR15, and STRL33 as coreceptors by diverse human immunodeficiency virus type 1 and simian immunodeficiency virus envelope proteins. Edinger, A.L., Hoffman, T.L., Sharron, M., Lee, B., O'Dowd, B., Doms, R.W. Virology (1998)
- Two orphan seven-transmembrane segment receptors which are expressed in CD4-positive cells support simian immunodeficiency virus infection. Farzan, M., Choe, H., Martin, K., Marcon, L., Hofmann, W., Karlsson, G., Sun, Y., Barrett, P., Marchand, N., Sullivan, N., Gerard, N., Gerard, C., Sodroski, J. J. Exp. Med. (1997)
- The function of simian chemokine receptors in the replication of SIV. Marx, P.A., Chen, Z. Semin. Immunol. (1998)
- Amino acid 324 in the simian immunodeficiency virus SIVmac V3 loop can confer CD4 independence and modulate the interaction with CCR5 and alternative coreceptors. Pöhlmann, S., Davis, C., Meister, S., Leslie, G.J., Otto, C., Reeves, J.D., Puffer, B.A., Papkalla, A., Krumbiegel, M., Marzi, A., Lorenz, S., Münch, J., Doms, R.W., Kirchhoff, F. J. Virol. (2004)
- The virotoxin model of HIV-1 enteropathy: involvement of GPR15/Bob and galactosylceramide in the cytopathic effects induced by HIV-1 gp120 in the HT-29-D4 intestinal cell line. Maresca, M., Mahfoud, R., Garmy, N., Kotler, D.P., Fantini, J., Clayton, F. J. Biomed. Sci. (2003)
- Co-receptor usage of BOB/GPR15 in addition to CCR5 has no significant effect on replication of simian immunodeficiency virus in vivo. Pöhlmann, S., Stolte, N., Münch, J., Ten Haaft, P., Heeney, J.L., Stahl-Hennig, C., Kirchhoff, F. J. Infect. Dis. (1999)
- A novel human gene encoding a G-protein-coupled receptor (GPR15) is located on chromosome 3. Heiber, M., Marchese, A., Nguyen, T., Heng, H.H., George, S.R., O'Dowd, B.F. Genomics (1996)
- Cloning and sequencing of cynomolgus macaque CCR3, GPR15, and STRL33: potential coreceptors for HIV type 1, HIV type 2, and SIV. Wade-Evans, A.M., Russell, J., Jenkins, A., Javan, C. AIDS Res. Hum. Retroviruses (2001)