The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

AC1LAHXN     6-(hexadecylamino)-3-[3,4,5- trihydroxy-6...

Synonyms: N-hexadecylamino-1-deoxylactitol
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of galactosylceramide


High impact information on galactosylceramide


Chemical compound and disease context of galactosylceramide


Biological context of galactosylceramide


Anatomical context of galactosylceramide


Associations of galactosylceramide with other chemical compounds


Gene context of galactosylceramide


Analytical, diagnostic and therapeutic context of galactosylceramide


  1. Primary intestinal epithelial cells selectively transfer R5 HIV-1 to CCR5+ cells. Meng, G., Wei, X., Wu, X., Sellers, M.T., Decker, J.M., Moldoveanu, Z., Orenstein, J.M., Graham, M.F., Kappes, J.C., Mestecky, J., Shaw, G.M., Smith, P.D. Nat. Med. (2002) [Pubmed]
  2. HIV-particles in spermatozoa of patients with AIDS and their transfer into the oocyte. Baccetti, B., Benedetto, A., Burrini, A.G., Collodel, G., Ceccarini, E.C., Crisà, N., Di Caro, A., Estenoz, M., Garbuglia, A.R., Massacesi, A. J. Cell Biol. (1994) [Pubmed]
  3. Galactosylceramide: a reliable serum index of demyelination in multiple sclerosis. Lubetzki, C., Thuillier, Y., Galli, A., Lyon-Caen, O., Lhermitte, F., Zalc, B. Ann. Neurol. (1989) [Pubmed]
  4. Galactosylceramide lipidosis: novel presentation as a slowly progressive spinocerebellar degeneration. Thomas, P.K., Halpern, J.P., King, R.H., Patrick, D. Ann. Neurol. (1984) [Pubmed]
  5. Metabolism of cerebroside sulfate and subcellular distribution of its metabolites in cultured skin fibroblasts from controls, metachromatic leukodystrophy, and globoid cell leukodystrophy. Inui, K., Furukawa, M., Okada, S., Yabuuchi, H. J. Clin. Invest. (1988) [Pubmed]
  6. Myelin basic protein-dependent plasma membrane reorganization in the formation of myelin. Fitzner, D., Schneider, A., Kippert, A., M??bius, W., Willig, K.I., Hell, S.W., Bunt, G., Gaus, K., Simons, M. EMBO J. (2006) [Pubmed]
  7. Inhibition of cytokinesis by a lipid metabolite, psychosine. Kanazawa, T., Nakamura, S., Momoi, M., Yamaji, T., Takematsu, H., Yano, H., Sabe, H., Yamamoto, A., Kawasaki, T., Kozutsumi, Y. J. Cell Biol. (2000) [Pubmed]
  8. Assembly of myelin by association of proteolipid protein with cholesterol- and galactosylceramide-rich membrane domains. Simons, M., Krämer, E.M., Thiele, C., Stoffel, W., Trotter, J. J. Cell Biol. (2000) [Pubmed]
  9. SPC3, a synthetic peptide derived from the V3 domain of human immunodeficiency virus type 1 (HIV-1) gp120, inhibits HIV-1 entry into CD4+ and CD4- cells by two distinct mechanisms. Yahi, N., Fantini, J., Baghdiguian, S., Mabrouk, K., Tamalet, C., Rochat, H., Van Rietschoten, J., Sabatier, J.M. Proc. Natl. Acad. Sci. U.S.A. (1995) [Pubmed]
  10. Glycosphingolipids of various human ovarian tumors: a significantly high expression of I3SO3GalCer and Lewis antigen in mucinous cystadenocarcinoma. Kiguchi, K., Takamatsu, K., Tanaka, J., Nozawa, S., Iwamori, M., Nagai, Y. Cancer Res. (1992) [Pubmed]
  11. Specific interaction of HIV-1 and HIV-2 surface envelope glycoproteins with monolayers of galactosylceramide and ganglioside GM3. Hammache, D., Piéroni, G., Yahi, N., Delézay, O., Koch, N., Lafont, H., Tamalet, C., Fantini, J. J. Biol. Chem. (1998) [Pubmed]
  12. Synthetic soluble analogs of galactosylceramide (GalCer) bind to the V3 domain of HIV-1 gp120 and inhibit HIV-1-induced fusion and entry. Fantini, J., Hammache, D., Delézay, O., Yahi, N., André-Barrès, C., Rico-Lattes, I., Lattes, A. J. Biol. Chem. (1997) [Pubmed]
  13. Co-expression of CXCR4/fusin and galactosylceramide in the human intestinal epithelial cell line HT-29. Delézay, O., Koch, N., Yahi, N., Hammache, D., Tourres, C., Tamalet, C., Fantini, J. AIDS (1997) [Pubmed]
  14. Presence of activator proteins for the enzymic hydrolysis of GM1 and GM2 gangliosides in normal human urine. Li, Y.T., Muhiudeen, I.A., DeGasperi, R., Hirabayashi, Y., Li, S.C. Am. J. Hum. Genet. (1983) [Pubmed]
  15. Paradoxical influence of acid beta-galactosidase gene dosage on phenotype of the twitcher mouse (genetic galactosylceramidase deficiency). Tohyama, J., Vanier, M.T., Suzuki, K., Ezoe, T., Matsuda, J., Suzuki, K. Hum. Mol. Genet. (2000) [Pubmed]
  16. Saposin A Mobilizes Lipids from Low Cholesterol and High Bis(monoacylglycerol)phosphate-containing Membranes: PATIENT VARIANT SAPOSIN A LACKS LIPID EXTRACTION CAPACITY. Locatelli-Hoops, S., Remmel, N., Klingenstein, R., Breiden, B., Rossocha, M., Schoeniger, M., Koenigs, C., Saenger, W., Sandhoff, K. J. Biol. Chem. (2006) [Pubmed]
  17. Cytoprotective effect of glucosylceramide synthase inhibition against daunorubicin-induced apoptosis in human leukemic cell lines. Grazide, S., Terrisse, A.D., Lerouge, S., Laurent, G., Jaffrézou, J.P. J. Biol. Chem. (2004) [Pubmed]
  18. Internalization and sorting of a fluorescent analogue of glucosylceramide to the Golgi apparatus of human skin fibroblasts: utilization of endocytic and nonendocytic transport mechanisms. Martin, O.C., Pagano, R.E. J. Cell Biol. (1994) [Pubmed]
  19. Sorting of newly synthesized galactosphingolipids to the two surface domains of epithelial cells. van der Bijl, P., Lopes-Cardozo, M., van Meer, G. J. Cell Biol. (1996) [Pubmed]
  20. Human immunodeficiency virus infection of human brain capillary endothelial cells occurs via a CD4/galactosylceramide-independent mechanism. Moses, A.V., Bloom, F.E., Pauza, C.D., Nelson, J.A. Proc. Natl. Acad. Sci. U.S.A. (1993) [Pubmed]
  21. Infection of colonic epithelial cell lines by type 1 human immunodeficiency virus is associated with cell surface expression of galactosylceramide, a potential alternative gp120 receptor. Fantini, J., Cook, D.G., Nathanson, N., Spitalnik, S.L., Gonzalez-Scarano, F. Proc. Natl. Acad. Sci. U.S.A. (1993) [Pubmed]
  22. Investigation of the calcium-mediated association between the carbohydrate head groups of galactosylceramide and galactosylceramide I3 sulfate by electrospray ionization mass spectrometry. Koshy, K.M., Boggs, J.M. J. Biol. Chem. (1996) [Pubmed]
  23. Epitope mapping for monoclonal antibodies identifies functional domains of pulmonary surfactant protein A that interact with lipids. Kuroki, Y., McCormack, F.X., Ogasawara, Y., Mason, R.J., Voelker, D.R. J. Biol. Chem. (1994) [Pubmed]
  24. Effect of myelin basic protein on the thermotropic behavior of aqueous dispersions of neutral and anionic glycosphingolipids and their mixtures with dipalmitoylphosphatidylcholine. Maggio, B., Sturtevant, J.M., Yu, R.K. J. Biol. Chem. (1987) [Pubmed]
  25. Cloning and expression of cDNA encoding human galactocerebrosidase, the enzyme deficient in globoid cell leukodystrophy. Chen, Y.Q., Rafi, M.A., de Gala, G., Wenger, D.A. Hum. Mol. Genet. (1993) [Pubmed]
  26. A new possible mechanism of human immunodeficiency virus type 1 infection of neural cells. Alvarez Losada, S., Cantó-Nogués, C., Muñoz-Fernández, M.A. Neurobiol. Dis. (2002) [Pubmed]
  27. Cell-associated HIV-1 infection of salivary gland epithelial cell lines. Moore, J.S., Hall, S.D., Jackson, S. Virology (2002) [Pubmed]
  28. Myelin proteolipid protein, basic protein, the small isoform of myelin-associated glycoprotein, and p42MAPK are associated in the Triton X-100 extract of central nervous system myelin. Arvanitis, D.N., Yang, W., Boggs, J.M. J. Neurosci. Res. (2002) [Pubmed]
  29. A galactosylceramide binding domain is involved in trafficking of CLN3 from Golgi to rafts via recycling endosomes. Persaud-Sawin, D.A., McNamara, J.O., Rylova, S., Vandongen, A., Boustany, R.M. Pediatr. Res. (2004) [Pubmed]
  30. Requirement for nonoligodendrocyte cell signals for enhanced myelinogenic gene expression in long-term cultures of purified rat oligodendrocytes. Bhat, S., Barbarese, E., Pfeiffer, S.E. Proc. Natl. Acad. Sci. U.S.A. (1981) [Pubmed]
  31. Synthesis of myelin glycosphingolipids (galactosylceramide and galactosyl(3-O-sulfate)ceramide (sulfatide)) by cloned cell lines derived from mouse neurotumors. Dawson, G., Sundarraj, N., Pfeiffer, S.E. J. Biol. Chem. (1977) [Pubmed]
  32. Piglet ileal mucus contains protein and glycolipid (galactosylceramide) receptors specific for Escherichia coli K88 fimbriae. Blomberg, L., Krivan, H.C., Cohen, P.S., Conway, P.L. Infect. Immun. (1993) [Pubmed]
  33. Macro-ripple phase formation in bilayers composed of galactosylceramide and phosphatidylcholine. Brown, R.E., Anderson, W.H., Kulkarni, V.S. Biophys. J. (1995) [Pubmed]
WikiGenes - Universities