Gene Review:
Tiam1 - T-cell lymphoma invasion and metastasis 1
Rattus norvegicus
- TrkB binds and tyrosine-phosphorylates Tiam1, leading to activation of Rac1 and induction of changes in cellular morphology. Miyamoto, Y., Yamauchi, J., Tanoue, A., Wu, C., Mobley, W.C. Proc. Natl. Acad. Sci. U.S.A. (2006)
- Ras activation of a Rac1 exchange factor, Tiam1, mediates neurotrophin-3-induced Schwann cell migration. Yamauchi, J., Miyamoto, Y., Tanoue, A., Shooter, E.M., Chan, J.R. Proc. Natl. Acad. Sci. U.S.A. (2005)
- Invasion of T-lymphoma cells: cooperation between Rho family GTPases and lysophospholipid receptor signaling. Stam, J.C., Michiels, F., van der Kammen, R.A., Moolenaar, W.H., Collard, J.G. EMBO J. (1998)
- Evidence for the involvement of Tiam1 in axon formation. Kunda, P., Paglini, G., Quiroga, S., Kosik, K., Caceres, A. J. Neurosci. (2001)
- The Rac1 guanine nucleotide exchange factor Tiam1 mediates EphB receptor-dependent dendritic spine development. Tolias, K.F., Bikoff, J.B., Kane, C.G., Tolias, C.S., Hu, L., Greenberg, M.E. Proc. Natl. Acad. Sci. U.S.A. (2007)