Gene Review:
IFRD1 - interferon-related developmental regulator 1
Homo sapiens
Synonyms:
Interferon-related developmental regulator 1, Nerve growth factor-inducible protein PC4, PC4, TIS7
- The human homolog of the rodent immediate early response genes, PC4 and TIS7, resides in the lung cancer tumor suppressor gene region on chromosome 3p21. Latif, F., Duh, F.M., Bader, S., Sekido, Y., Li, H., Geil, L., Zbar, B., Minna, J.D., Lerman, M.I. Hum. Genet. (1997)
- Early gene regulation by nerve growth factor in PC12 cells: induction of an interferon-related gene. Tirone, F., Shooter, E.M. Proc. Natl. Acad. Sci. U.S.A. (1989)
- Transcriptional Coactivator PC4, a Chromatin-Associated Protein, Induces Chromatin Condensation. Das, C., Hizume, K., Batta, K., Kumar, B.R., Gadad, S.S., Ganguly, S., Lorain, S., Verreault, A., Sadhale, P.P., Takeyasu, K., Kundu, T.K. Mol. Cell. Biol. (2006)
- Cloning of the human interferon-related developmental regulator (IFRD1) gene coding for the PC4 protein, a member of a novel family of developmentally regulated genes. Buanne, P., Incerti, B., Guardavaccaro, D., Avvantaggiato, V., Simeone, A., Tirone, F. Genomics (1998)
- Nerve growth factor regulates the subcellular localization of the nerve growth factor-inducible protein PC4 in PC12 cells. Guardavaccaro, D., Montagnoli, A., Ciotti, M.T., Gatti, A., Lotti, L., Di Lazzaro, C., Torrisi, M.R., Tirone, F. J. Neurosci. Res. (1994)
- Inhibition of differentiation in myoblasts deprived of the interferon-related protein PC4. Guardavaccaro, D., Ciotti, M.T., Schäfer, B.W., Montagnoli, A., Tirone, F. Cell Growth Differ. (1995)
- The VP16 Activation Domain Establishes an Active Mediator Lacking CDK8 in Vivo. Uhlmann, T., Boeing, S., Lehmbacher, M., Meisterernst, M. J. Biol. Chem. (2007)
- Differentially expressed genes in hemocytes of Vibrio harveyi-challenged shrimp Penaeus monodon. Somboonwiwat, K., Supungul, P., Rimphanitchayakit, V., Aoki, T., Hirono, I., Tassanakajon, A. J. Biochem. Mol. Biol. (2006)
- Gradual phosphorylation regulates PC4 coactivator function. Jonker, H.R., Wechselberger, R.W., Pinkse, M., Kaptein, R., Folkers, G.E. FEBS J. (2006)