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Gene Review

LINC01194  -  long intergenic non-protein coding RNA 1194

Homo sapiens

Synonyms: CT49, TAG
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Disease relevance of TAG


High impact information on TAG


Biological context of TAG


Anatomical context of TAG


Regulatory relationships of TAG


Other interactions of TAG

  • Tumor-antigen 4 immunoreactivity was present in the cytoplasm of many SCC tissues, especially in the hyperparakeratotic region, and in the cytoplasm of differentiated squamous cells of the intermediate layer of normal epithelia of various organs, but not in those of other types of lung cancers or benign pulmonary diseases [18].
  • Striking Immunodominance Hierarchy of Naturally Occurring CD8+ and CD4+ T Cell Responses to Tumor Antigen NY-ESO-1 [21].

Analytical, diagnostic and therapeutic context of TAG


  1. Tumor antigen induction by the envelope-defective Bryan strain of Rous sarcoma viruses. Kurth, R., Kitchener, G. J. Natl. Cancer Inst. (1978) [Pubmed]
  2. Cell-mediated antitumor immunity in breast cancer patients evaluated by antigen-induced leukocyte adherence inhibition in test tubes. Grosser, N., Thomson, D.M. Cancer Res. (1975) [Pubmed]
  3. Tumor antigen expression in melanoma varies according to antigen and stage. Barrow, C., Browning, J., MacGregor, D., Davis, I.D., Sturrock, S., Jungbluth, A.A., Cebon, J. Clin. Cancer Res. (2006) [Pubmed]
  4. The expression of mouse gene P1A in testis does not prevent safe induction of cytolytic T cells against a P1A-encoded tumor antigen. Uyttenhove, C., Godfraind, C., Lethé, B., Amar-Costesec, A., Renauld, J.C., Gajewski, T.F., Duffour, M.T., Warnier, G., Boon, T., Van den Eynde, B.J. Int. J. Cancer (1997) [Pubmed]
  5. Tumor-antigen heterogeneity of disseminated breast cancer cells: implications for immunotherapy of minimal residual disease. Braun, S., Hepp, F., Sommer, H.L., Pantel, K. Int. J. Cancer (1999) [Pubmed]
  6. Tumor antigen and human chorionic gonadotropin in CaSki cells: a new epidermoid cervical cancer cell line. Pattillo, R.A., Hussa, R.O., Story, M.T., Ruckert, A.C., Shalaby, M.R., Mattingly, R.F. Science (1977) [Pubmed]
  7. Tumor antigen-specific immunization of bone marrow transplantation donors as adoptive therapy against established tumor. Hornung, R.L., Longo, D.L., Bowersox, O.C., Kwak, L.W. J. Natl. Cancer Inst. (1995) [Pubmed]
  8. Corrigendum: Tumor antigen-specific induction of transcriptionally targeted retroviral vectors from chimeric immune receptor-modified T cells. Chester, J., Ruchatz, A., Gough, M., Crittenden, M., Chong, H., Lo??c-Cosset, F., Diaz, R.M., Harrington, K., Alvarez-Vallina, L., Vile, R. Nat. Biotechnol. (2006) [Pubmed]
  9. Tumor antigen processing and presentation depend critically on dendritic cell type and the mode of antigen delivery. Schnurr, M., Chen, Q., Shin, A., Chen, W., Toy, T., Jenderek, C., Green, S., Miloradovic, L., Drane, D., Davis, I.D., Villadangos, J., Shortman, K., Maraskovsky, E., Cebon, J. Blood (2005) [Pubmed]
  10. Generation of tumor-specific, HLA class I-restricted human Th1 and Tc1 cells by cell engineering with tumor peptide-specific T-cell receptor genes. Tsuji, T., Yasukawa, M., Matsuzaki, J., Ohkuri, T., Chamoto, K., Wakita, D., Azuma, T., Niiya, H., Miyoshi, H., Kuzushima, K., Oka, Y., Sugiyama, H., Ikeda, H., Nishimura, T. Blood (2005) [Pubmed]
  11. Lack of ignorance to tumor antigens: evaluation using nominal antigen transfection and T-cell receptor transgenic lymphocytes in Lyons-Parish analysis--implications for tumor tolerance. Robinson, B.W., Scott, B.M., Lake, R.A., Stumbles, P.A., Nelson, D.J., Fisher, S., Marzo, A.L. Clin. Cancer Res. (2001) [Pubmed]
  12. Tumor antigen HuR binds specifically to one of five protein-binding segments in the 3'-untranslated region of the neurofibromin messenger RNA. Haeussler, J., Haeusler, J., Striebel, A.M., Assum, G., Vogel, W., Furneaux, H., Krone, W. Biochem. Biophys. Res. Commun. (2000) [Pubmed]
  13. Technology evaluation: Canvaxin, John Wayne Cancer Institute/CancerVax. Motl, S.E. Curr. Opin. Mol. Ther. (2004) [Pubmed]
  14. Tumor antigen phenotype, biologic staging, and prognosis in head and neck squamous carcinoma. Wolf, G.T., Carey, T.E. J. Natl. Cancer Inst. Monographs (1992) [Pubmed]
  15. Tumor antigen-specific T helper cells in cancer immunity and immunotherapy. Knutson, K.L., Disis, M.L. Cancer Immunol. Immunother. (2005) [Pubmed]
  16. Tumor antigen immunization of sibling stem cell transplant donors in multiple myeloma. Neelapu, S.S., Munshi, N.C., Jagannath, S., Watson, T.M., Pennington, R., Reynolds, C., Barlogie, B., Kwak, L.W. Bone Marrow Transplant. (2005) [Pubmed]
  17. Immunological ignorance of solid tumors. Ochsenbein, A.F. Springer Semin. Immunopathol. (2005) [Pubmed]
  18. Tumor-antigen 4. Its immunohistochemical distribution and tissue and serum concentrations in squamous cell carcinoma of the lung and esophagus. Mino-Miyagawa, N., Kimura, Y., Hamamoto, K. Cancer (1990) [Pubmed]
  19. Effect of human tumor antigens on the active E-rosette-forming test (ARFT): a new diagnostic method for cancer. Wang, K. Clin. Immunol. Immunopathol. (1984) [Pubmed]
  20. NKT and CD8 lymphocytes mediate suppression of hepatocellular carcinoma growth via tumor antigen-pulsed dendritic cells. Shibolet, O., Alper, R., Zlotogarov, L., Thalenfeld, B., Engelhardt, D., Rabbani, E., Ilan, Y. Int. J. Cancer (2003) [Pubmed]
  21. Striking Immunodominance Hierarchy of Naturally Occurring CD8+ and CD4+ T Cell Responses to Tumor Antigen NY-ESO-1. Jackson, H., Dimopoulos, N., Mifsud, N.A., Tai, T.Y., Chen, Q., Svobodova, S., Browning, J., Luescher, I., Stockert, L., Old, L.J., Davis, I.D., Cebon, J., Chen, W. J. Immunol. (2006) [Pubmed]
  22. Mannan-MUC1-pulsed dendritic cell immunotherapy: a phase I trial in patients with adenocarcinoma. Loveland, B.E., Zhao, A., White, S., Gan, H., Hamilton, K., Xing, P.X., Pietersz, G.A., Apostolopoulos, V., Vaughan, H., Karanikas, V., Kyriakou, P., McKenzie, I.F., Mitchell, P.L. Clin. Cancer Res. (2006) [Pubmed]
  23. Dendritic cells in vaccination therapies of human malignant disease. Reichardt, V.L., Brossart, P., Kanz, L. Blood Rev. (2004) [Pubmed]
  24. Tumor antigen NB/70K and CA 125 levels in the blood of preoperative ovarian cancer patients and controls: a preliminary report of the use of the NB12123 and CA 125 radioimmunoassays alone and in combination. Knauf, S., Bast, R.C. Int. J. Biol. Markers (1988) [Pubmed]
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