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MeSH Review

T-Lymphocytes, Helper-Inducer

 
 
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Disease relevance of T-Lymphocytes, Helper-Inducer

 

Psychiatry related information on T-Lymphocytes, Helper-Inducer

  • Compared with wakefulness, early nocturnal sleep induced a shift in the Th1/Th2 cytokine balance towards increased Th1 activity, as indicated by an increased (p <.05) ratio of IFN-gamma/IL-4 producing T helper cells [6].
 

High impact information on T-Lymphocytes, Helper-Inducer

  • A newly identified activation antigen of helper T cells, a ligand for the B cell differentiation antigen, CD40, is a key component of contact help [7].
  • On the basis of the studies discussed in the first section, it appears that the recruitment of most helper-T cell clones takes place by APC that can internalize and process the protein antigens, be they soluble or part of the structure of microorganisms [8].
  • Naive T helper cells differentiate into two subsets, Th1 and Th2, each with distinct functions and cytokine profiles [9].
  • Distinct roles for the costimulatory ligands B7-1 and B7-2 in T helper cell differentiation [10]?
  • Our results suggest that the T cell ligand of CD22 is CD45RO, an isoform of the leukocyte common antigen class of phosphotyrosine phosphatases associated with the helper T cell phenotype [11].
 

Chemical compound and disease context of T-Lymphocytes, Helper-Inducer

 

Biological context of T-Lymphocytes, Helper-Inducer

 

Anatomical context of T-Lymphocytes, Helper-Inducer

 

Associations of T-Lymphocytes, Helper-Inducer with chemical compounds

  • Two human helper T cell determinants in influenza have been identified, one in the hemagglutinin and the other in the matrix protein (M1) [27].
  • The T-cell surface glycoprotein, CD4, is expressed predominantly on helper T cells and is thought to play a major role in cell-cell interactions [28].
  • The mitogen-activated protein kinases ERK-1 and ERK-2 and the guanosine triphosphate-binding protein p21ras were found to remain unactivated upon stimulation of anergic murine T helper cell 1 clones [29].
  • Soluble IL-7 administered to TRAF6(-/-) embryos was sufficient to restore LN genesis indicating the functional similarities of the IL-7R(alpha)(+) inducer cells for LN and PP genesis [30].
  • Here we present evidence that CD4 affects the responsiveness of T helper cells by controlling spatial localization of the tyrosine kinase Lck in the synapse [31].
 

Gene context of T-Lymphocytes, Helper-Inducer

 

Analytical, diagnostic and therapeutic context of T-Lymphocytes, Helper-Inducer

References

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