Gene Review:
COMT - catechol-O-methyltransferase
Canis lupus familiaris
- Effects of pharmacologic alterations of adrenergic mechanisms by cocaine, tropolone, aminophylline, and ketamine on epinephrine-induced arrhythmias during halothane-nitrous oxide anesthesia. Koehntop, D.E., Liao, J.C., Van Bergen, F.H. Anesthesiology (1977)
- Effects of tolcapone, a catechol-O-methyltransferase inhibitor, and Sinemet on intestinal electrolyte and fluid transport in conscious dogs. Larsen, K.R., Dajani, E.Z., Dajani, N.E., Dayton, M.T., Moore, J.G. Dig. Dis. Sci. (1998)
- Evidence for the beta-adrenergic receptor regulation of membrane-bound catechol-O-methyltransferase activity in myocardium. Wrenn, S., Homcy, C., Haber, E. J. Biol. Chem. (1979)
- Inactivation of norepinephrine in an isolated vein. Brandao, F. J. Pharmacol. Exp. Ther. (1977)
- Release and disposition of 3H-noradrenaline in the saphenous vein of neonate and adult dogs. Moura, D., Vaz-da-Silva, M.J., Azevedo, I., Brandão, F., Guimarães, S. Naunyn Schmiedebergs Arch. Pharmacol. (1993)
- Identification of major metabolites of the catechol-O-methyltransferase inhibitor nitecapone in the rat and dog. Wikberg, T., Taskinen, J. Drug Metab. Dispos. (1993)
- Breed differences in genotype and allele frequency of catechol O-methyltransferase gene polymorphic regions in dogs. Masuda, K., Hashizume, C., Kikusui, T., Takeuchi, Y., Mori, Y. J. Vet. Med. Sci. (2004)
- Relation between the amount of smooth muscle of venous tissue and the degree of supersensitivity to isoprenaline caused by inhibition of catechol-O-methyl transferase. Guimarães, S., Azevedo, I., Cardoso, W., Oliveira, M.C. Naunyn Schmiedebergs Arch. Pharmacol. (1975)
- Two different biophases for adrenaline released by electrical stimulation or tyramine from the sympathetic nerve endings of the dog saphenous vein. Guimarães, S., Paiva, M.Q. Naunyn Schmiedebergs Arch. Pharmacol. (1981)
- Effect of catechol-O-methyl-transferase (COMT) inhibition on the vascular and metabolic responses to noradrenaline, isoprenaline and sympathetic nerve stimulation in canine subcutaneous adipose tissue. Belfrage, E., Fredholm, B.B., Rosell, S. Naunyn Schmiedebergs Arch. Pharmacol. (1977)
- The influence of monoamine oxidase activity on the release of noradrenaline by tyramine. Brandão, F., Araújo, D., Monteriro, J.G. J. Pharm. Pharmacol. (1989)
- Effect of cooling on COMT activity in canine saphenous vein homogenates determined by a micro radioenzymatic assay. Janssens, W.J., Vanhoutte, P.M. Archives internationales de pharmacodynamie et de thérapie. (1978)
- Inactivation and excretion of dopamine by the cat kidney in vivo. Stöcker, W., Hempel, K. Naunyn Schmiedebergs Arch. Pharmacol. (1976)
- The monoamine oxidase and catechol-O-methyltransferase activities in the dog liver. Ong, H., Yamaguchi, N. Can. J. Physiol. Pharmacol. (1982)
- Pharmacological studies on a new thymoleptic antidepressant, 1-[3-(dimethylamino)propyl]-5-methyl-3-phenyl-1H-indazole (FS-32). Ikeda, Y., Takano, N., Matsushita, H., Shiraki, Y., Koide, T., Nagashima, R., Fujimura, Y., Shindo, M., Suzuki, S., Iwasaki, T. Arzneimittel-Forschung. (1979)
- A comparative study of the role played by some inactivation pathways in the disposition of the transmitter in the rabbit aorta and the saphenous vein of the dog. Brandão, F. Blood vessels. (1976)
- An unusually important role of O-methylation in the disposition of noradrenaline and adrenaline by the dog renal artery. Nunes, J.P., Vaz-Da-Silva, M.J., Brandão, F., Guimarães, S. Archives internationales de pharmacodynamie et de thérapie. (1987)
- Myocardial ischemia stimulates catecholamine synthesis and catabolism in the dog adrenal medulla. Parvez, H., Ichihara, K., Parvez, S., Sakai, K., Abiko, Y., Nagatsu, T. Japanese heart journal. (1986)