Gene Review:
PCBP2 - poly(rC) binding protein 2
Homo sapiens
Synonyms:
Alpha-CP2, HNRNPE2, HNRPE2, Heterogeneous nuclear ribonucleoprotein E2, Poly(rC)-binding protein 2, ...
- The N-terminal K homology domain of the poly(rC)-binding protein is a major determinant for binding to the poliovirus 5'-untranslated region and acts as an inhibitor of viral translation. Silvera, D., Gamarnik, A.V., Andino, R. J. Biol. Chem. (1999)
- Poly(rC) binding protein 2 binds to stem-loop IV of the poliovirus RNA 5' noncoding region: identification by automated liquid chromatography-tandem mass spectrometry. Blyn, L.B., Swiderek, K.M., Richards, O., Stahl, D.C., Semler, B.L., Ehrenfeld, E. Proc. Natl. Acad. Sci. U.S.A. (1996)
- A nucleo-cytoplasmic SR protein functions in viral IRES-mediated translation initiation. Bedard, K.M., Daijogo, S., Semler, B.L. EMBO J. (2007)
- Interaction of poly(rC) binding protein 2 with the 5' noncoding region of hepatitis A virus RNA and its effects on translation. Graff, J., Cha, J., Blyn, L.B., Ehrenfeld, E. J. Virol. (1998)
- Differential utilization of poly(rC) binding protein 2 in translation directed by picornavirus IRES elements. Walter, B.L., Nguyen, J.H., Ehrenfeld, E., Semler, B.L. RNA (1999)
- BCR-ABL suppresses C/EBPalpha expression through inhibitory action of hnRNP E2. Perrotti, D., Cesi, V., Trotta, R., Guerzoni, C., Santilli, G., Campbell, K., Iervolino, A., Condorelli, F., Gambacorti-Passerini, C., Caligiuri, M.A., Calabretta, B. Nat. Genet. (2002)
- HnRNP L represses exon splicing via a regulated exonic splicing silencer. Rothrock, C.R., House, A.E., Lynch, K.W. EMBO J. (2005)
- Identification of two KH domain proteins in the alpha-globin mRNP stability complex. Kiledjian, M., Wang, X., Liebhaber, S.A. EMBO J. (1995)
- Selection and cloning of poly(rC)-binding protein 2 and Raf kinase inhibitor protein RNA activators of 2',5'-oligoadenylate synthetase from prostate cancer cells. Molinaro, R.J., Jha, B.K., Malathi, K., Varambally, S., Chinnaiyan, A.M., Silverman, R.H. Nucleic Acids Res. (2006)
- Distinct poly(rC) binding protein KH domain determinants for poliovirus translation initiation and viral RNA replication. Walter, B.L., Parsley, T.B., Ehrenfeld, E., Semler, B.L. J. Virol. (2002)
- Crystal structure of the first KH domain of human poly(C)-binding protein-2 in complex with a C-rich strand of human telomeric DNA at 1.7 A. Du, Z., Lee, J.K., Tjhen, R., Li, S., Pan, H., Stroud, R.M., James, T.L. J. Biol. Chem. (2005)
- NMR structures of loop B RNAs from the stem-loop IV domain of the enterovirus internal ribosome entry site: a single C to U substitution drastically changes the shape and flexibility of RNA. Du, Z., Ulyanov, N.B., Yu, J., Andino, R., James, T.L. Biochemistry (2004)
- Requirement of poly(rC) binding protein 2 for translation of poliovirus RNA. Blyn, L.B., Towner, J.S., Semler, B.L., Ehrenfeld, E. J. Virol. (1997)
- Two functional complexes formed by KH domain containing proteins with the 5' noncoding region of poliovirus RNA. Gamarnik, A.V., Andino, R. RNA (1997)
- Interaction of poly(rC)-binding protein 2 with the 5'-terminal stem loop of the hepatitis C-virus genome. Fukushi, S., Okada, M., Kageyama, T., Hoshino, F.B., Nagai, K., Katayama, K. Virus Res. (2001)
- Protein-protein interaction among hnRNPs shuttling between nucleus and cytoplasm. Kim, J.H., Hahm, B., Kim, Y.K., Choi, M., Jang, S.K. J. Mol. Biol. (2000)
- Hepatitis C virus internal ribosome entry site-dependent translation in Saccharomyces cerevisiae is independent of polypyrimidine tract-binding protein, poly(rC)-binding protein 2, and La protein. Rosenfeld, A.B., Racaniello, V.R. J. Virol. (2005)
- Promoter elements and erythroid cell nuclear factors that regulate alpha-globin gene transcription in vitro. Kim, C.G., Swendeman, S.L., Barnhart, K.M., Sheffery, M. Mol. Cell. Biol. (1990)
- Characterization of a family of related cellular transcription factors which can modulate human immunodeficiency virus type 1 transcription in vitro. Yoon, J.B., Li, G., Roeder, R.G. Mol. Cell. Biol. (1994)
- Cellular and molecular effects of a pulse butyrate regimen and new inducers of globin gene expression and hematopoiesis. Ikuta, T., Atweh, G., Boosalis, V., White, G.L., Da Fonseca, S., Boosalis, M., Faller, D.V., Perrine, S.P. Ann. N. Y. Acad. Sci. (1998)