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MeSH Review

Microbial Viability

 
 
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Disease relevance of Microbial Viability

 

High impact information on Microbial Viability

  • The 3'-untranslated region harbors a tRNA-like structure (TLS) to which a valine moiety can be added and it is indispensable for virus viability [6].
  • Uptake of H. pylori was inhibited by ammonium chloride and chloroquine at concentrations that did not effect either adherence or bacterial viability [7].
  • Stem-loop IV RNA containing a three nucleotide insertion that abrogates translation activity and virus viability was unable to bind PCBP2 [8].
  • Biochemical analysis of 3Dpol derivatives containing the thumb or palm substitutions revealed that these derivatives are both incapable of forming long fibers, suggesting that polymerase fibers are not essential for virus viability [9].
  • The possibility that this region of the protein may be sufficient for virus viability is discussed in relation to the sequences of NS1 genes of field isolates and to the phenotype of known viral mutants affected in the NS1 gene [10].
 

Chemical compound and disease context of Microbial Viability

 

Biological context of Microbial Viability

 

Anatomical context of Microbial Viability

  • The effector protein EspF, while critical for disruption of epithelial barrier function through alteration of tight junctions, is not required for bacterial viability or attachment [17].
  • RESULTS--Homogenisation of sputum using dithiothreitol increased the recovery of viable bacteria compared with sterile glass beads and/or saline, with no apparent effect on bacterial viability when incubated with culture broths [18].
  • There was however no significant enhancement of intracellular BCG growth, over a 7-day incubation, in human monocyte-derived macrophages in the presence of any of the TNF-alpha-blocking agents, as determined by both radiometric and CFU counting methods of assessing bacterial viability and growth [19].
 

Associations of Microbial Viability with chemical compounds

 

Gene context of Microbial Viability

 

Analytical, diagnostic and therapeutic context of Microbial Viability

References

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  8. Poly(rC) binding protein 2 binds to stem-loop IV of the poliovirus RNA 5' noncoding region: identification by automated liquid chromatography-tandem mass spectrometry. Blyn, L.B., Swiderek, K.M., Richards, O., Stahl, D.C., Semler, B.L., Ehrenfeld, E. Proc. Natl. Acad. Sci. U.S.A. (1996) [Pubmed]
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  19. Effect of blocking TNF-alpha on intracellular BCG (Bacillus Calmette Guerin) growth in human monocyte-derived macrophages. Fazal, N., Lammas, D.A., Raykundalia, C., Bartlett, R., Kumararatne, D.S. FEMS microbiology immunology. (1992) [Pubmed]
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  21. Parameters that influence the efficiency of processing antigenic epitopes expressed in Salmonella typhimurium. Wick, M.J., Harding, C.V., Normark, S.J., Pfeifer, J.D. Infect. Immun. (1994) [Pubmed]
  22. Intracellular activity of azithromycin against bacterial enteric pathogens. Rakita, R.M., Jacques-Palaz, K., Murray, B.E. Antimicrob. Agents Chemother. (1994) [Pubmed]
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  29. Isolation and characterization of the Escherichia coli htrB gene, whose product is essential for bacterial viability above 33 degrees C in rich media. Karow, M., Fayet, O., Cegielska, A., Ziegelhoffer, T., Georgopoulos, C. J. Bacteriol. (1991) [Pubmed]
  30. Use of HT-29, a cultured human colon cancer cell line, to study the effect of fermented milks on colon cancer cell growth and differentiation. Baricault, L., Denariaz, G., Houri, J.J., Bouley, C., Sapin, C., Trugnan, G. Carcinogenesis (1995) [Pubmed]
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