Gene Review:
SLC5A2 - solute carrier family 5 (sodium/glucose...
Homo sapiens
Synonyms:
Low affinity sodium-glucose cotransporter, Na(+)/glucose cotransporter 2, SGLT2, Sodium/glucose cotransporter 2, Solute carrier family 5 member 2
- Thyroid hormone regulation of the Na+/glucose cotransporter SGLT1 in Caco-2 cells. Matosin-Matekalo, M., Mesonero, J.E., Delezay, O., Poiree, J.C., Ilundain, A.A., Brot-Laroche, E. Biochem. J. (1998)
- SGLT gene expression in primary lung cancers and their metastatic lesions. Ishikawa, N., Oguri, T., Isobe, T., Fujitaka, K., Kohno, N. Jpn. J. Cancer Res. (2001)
- The human kidney low affinity Na+/glucose cotransporter SGLT2. Delineation of the major renal reabsorptive mechanism for D-glucose. Kanai, Y., Lee, W.S., You, G., Brown, D., Hediger, M.A. J. Clin. Invest. (1994)
- Glucose transporters in human renal proximal tubular cells isolated from the urine of patients with non-insulin-dependent diabetes. Rahmoune, H., Thompson, P.W., Ward, J.M., Smith, C.D., Hong, G., Brown, J. Diabetes (2005)
- HNF1alpha controls renal glucose reabsorption in mouse and man. Pontoglio, M., Prié, D., Cheret, C., Doyen, A., Leroy, C., Froguel, P., Velho, G., Yaniv, M., Friedlander, G. EMBO Rep. (2000)
- A novel missense mutation in SLC5A2 encoding SGLT2 underlies autosomal-recessive renal glucosuria and aminoaciduria. Magen, D., Sprecher, E., Zelikovic, I., Skorecki, K. Kidney Int. (2005)
- Localization of the Na+/glucose cotransporter gene SGLT2 to human chromosome 16 close to the centromere. Wells, R.G., Mohandas, T.K., Hediger, M.A. Genomics (1993)
- Human cardiomyocytes express high level of Na+/glucose cotransporter 1 (SGLT1). Zhou, L., Cryan, E.V., D'Andrea, M.R., Belkowski, S., Conway, B.R., Demarest, K.T. J. Cell. Biochem. (2003)
- High glucose levels down-regulate glucose transporter expression that correlates with increased oxidative stress in placental trophoblast cells in vitro. Li, H., Gu, Y., Zhang, Y., Lucas, M.J., Wang, Y. J. Soc. Gynecol. Investig. (2004)
- Cloning and expression of bovine sodium/glucose cotransporter SGLT2. Zhao, F.Q., McFadden, T.B., Wall, E.H., Dong, B., Zheng, Y.C. J. Dairy Sci. (2005)
- Synthesis and biologic evaluation of (11)c-methyl-d-glucoside, a tracer of the sodium-dependent glucose transporters. Bormans, G.M., Van Oosterwyck, G., De Groot, T.J., Veyhl, M., Mortelmans, L., Verbruggen, A.M., Koepsell, H. J. Nucl. Med. (2003)
- Renal glucosuria due to SGLT2 mutations. Kleta, R., Stuart, C., Gill, F.A., Gahl, W.A. Mol. Genet. Metab. (2004)
- Autosomal recessive renal glucosuria attributable to a mutation in the sodium glucose cotransporter (SGLT2). van den Heuvel, L.P., Assink, K., Willemsen, M., Monnens, L. Hum. Genet. (2002)
- Familial renal glucosuria: SLC5A2 mutation analysis and evidence of salt-wasting. Calado, J., Loeffler, J., Sakallioglu, O., Gok, F., Lhotta, K., Barata, J., Rueff, J. Kidney Int. (2006)
- High glucose reduces albumin uptake in cultured proximal tubular cells (LLC-PK1). Ishibashi, F. Diabetes Res. Clin. Pract. (2004)
- Renal transplantation modulates expression and function of receptors and transporters of rat proximal tubules. Velic, A., Hirsch, J.R., Bartel, J., Thomas, R., Schröter, R., Stegemann, H., Edemir, B., August, C., Schlatter, E., Gabriëls, G. J. Am. Soc. Nephrol. (2004)