Gene Review:
SRP54 - signal recognition particle 54kDa
Homo sapiens
Synonyms:
Signal recognition particle 54 kDa protein
Sauer-Eriksson,
Hainzl,
Singh,
Dani,
Sharma,
Steinberg,
Römisch,
Miller,
Dobberstein,
High,
Hainzl,
Huang,
Sauer-Eriksson,
Bacher,
Lütcke,
Jungnickel,
Rapoport,
Dobberstein,
- E. coli 4.5S RNA is part of a ribonucleoprotein particle that has properties related to signal recognition particle. Ribes, V., Römisch, K., Giner, A., Dobberstein, B., Tollervey, D. Cell (1990)
- Human autoantibodies against the 54 kDa protein of the signal recognition particle block function at multiple stages. Römisch, K., Miller, F.W., Dobberstein, B., High, S. Arthritis Res. Ther. (2006)
- Structure of the SRP19 RNA complex and implications for signal recognition particle assembly. Hainzl, T., Huang, S., Sauer-Eriksson, A.E. Nature (2002)
- Regulation by the ribosome of the GTPase of the signal-recognition particle during protein targeting. Bacher, G., Lütcke, H., Jungnickel, B., Rapoport, T.A., Dobberstein, B. Nature (1996)
- Crystal structure of SRP19 in complex with the S domain of SRP RNA and its implication for the assembly of the signal recognition particle. Oubridge, C., Kuglstatter, A., Jovine, L., Nagai, K. Mol. Cell (2002)
- The methionine-rich domain of the 54 kDa subunit of signal recognition particle is sufficient for the interaction with signal sequences. Lütcke, H., High, S., Römisch, K., Ashford, A.J., Dobberstein, B. EMBO J. (1992)
- Assembly of the human signal recognition particle (SRP): overlap of regions required for binding of protein SRP54 and assembly control. Yin, J., Yang, C.H., Zwieb, C. RNA (2001)
- Protein SRP54 of human signal recognition particle: cloning, expression, and comparative analysis of functional sites. Gowda, K., Black, S.D., Moeller, I., Sakakibara, Y., Liu, M.C., Zwieb, C. Gene (1998)
- S-domain assembly of the signal recognition particle. Sauer-Eriksson, A.E., Hainzl, T. Curr. Opin. Struct. Biol. (2003)
- RNA interference of signal peptide-binding protein SRP54 elicits deleterious effects and protein sorting defects in trypanosomes. Liu, L., Liang, X.H., Uliel, S., Unger, R., Ullu, E., Michaeli, S. J. Biol. Chem. (2002)
- Crystal structure of the conserved subdomain of human protein SRP54M at 2.1 A resolution: evidence for the mechanism of signal peptide binding. Clemons, W.M., Gowda, K., Black, S.D., Zwieb, C., Ramakrishnan, V. J. Mol. Biol. (1999)
- A chloroplast homologue of the signal recognition particle subunit SRP54 is involved in the posttranslational integration of a protein into thylakoid membranes. Li, X., Henry, R., Yuan, J., Cline, K., Hoffman, N.E. Proc. Natl. Acad. Sci. U.S.A. (1995)
- A structure for the signal sequence binding protein SRP54: 3D reconstruction from STEM images of single molecules. Czarnota, G.J., Andrews, D.W., Farrow, N.A., Ottensmeyer, F.P. J. Struct. Biol. (1994)
- Binding site of the M-domain of human protein SRP54 determined by systematic site-directed mutagenesis of signal recognition particle RNA. Gowda, K., Chittenden, K., Zwieb, C. Nucleic Acids Res. (1997)
- Genetic and biochemical analysis of the fission yeast ribonucleoprotein particle containing a homolog of Srp54p. Selinger, D., Brennwald, P., Althoff, S., Reich, C., Hann, B., Walter, P., Wise, J.A. Nucleic Acids Res. (1994)
- Induced structural changes of 7SL RNA during the assembly of human signal recognition particle. Kuglstatter, A., Oubridge, C., Nagai, K. Nat. Struct. Biol. (2002)
- A GTPase cycle in initiation of protein translocation across the endoplasmic reticulum membrane. Miller, J.D., Walter, P. Ciba Found. Symp. (1993)
- Molecular evolution of SRP cycle components: functional implications. Althoff, S., Selinger, D., Wise, J.A. Nucleic Acids Res. (1994)
- Signal recognition particle components in the nucleolus. Politz, J.C., Yarovoi, S., Kilroy, S.M., Gowda, K., Zwieb, C., Pederson, T. Proc. Natl. Acad. Sci. U.S.A. (2000)
- Inhibition of the biosynthesis of SRP polypeptides and secretory proteins by aflatoxin B(1) can disrupt protein targeting. Singh, J., Dani, H.M., Sharma, R., Steinberg, P. Cell Biochem. Funct. (2006)
- Expression, purification, and crystallography of the conserved methionine-rich domain of human signal recognition particle 54 kDa protein. Gowda, K., Clemons, W.M., Zwieb, C., Black, S.D. Protein Sci. (1999)