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Disease relevance of Polymyositis


Psychiatry related information on Polymyositis

  • Analyses of 19 sera samples from patients with polymyositis showed no antinuclear antibodies, excluding a 40% prevalence of the 16/6 Id [6].

High impact information on Polymyositis


Chemical compound and disease context of Polymyositis


Biological context of Polymyositis


Anatomical context of Polymyositis


Gene context of Polymyositis


Analytical, diagnostic and therapeutic context of Polymyositis


  1. Histidyl-tRNA synthetase and asparaginyl-tRNA synthetase, autoantigens in myositis, activate chemokine receptors on T lymphocytes and immature dendritic cells. Howard, O.M., Dong, H.F., Yang, D., Raben, N., Nagaraju, K., Rosen, A., Casciola-Rosen, L., Härtlein, M., Kron, M., Yang, D., Yiadom, K., Dwivedi, S., Plotz, P.H., Oppenheim, J.J. J. Exp. Med. (2002) [Pubmed]
  2. The development of fatal myocarditis and polymyositis in mice heterozygous for IFN-gamma and lacking the SOCS-1 gene. Metcalf, D., Di Rago, L., Mifsud, S., Hartley, L., Alexander, W.S. Proc. Natl. Acad. Sci. U.S.A. (2000) [Pubmed]
  3. Heterogeneity of human skeletal muscle tropomyosin. Giometti, C.S., Danon, M.J. Ann. Neurol. (1985) [Pubmed]
  4. Inclusion body myositis: clinical and pathological boundaries. Amato, A.A., Gronseth, G.S., Jackson, C.E., Wolfe, G.I., Katz, J.S., Bryan, W.W., Barohn, R.J. Ann. Neurol. (1996) [Pubmed]
  5. Serum interleukin-2 concentrations in Guillain-Barré syndrome and chronic idiopathic demyelinating polyradiculoneuropathy: comparison with other neurological diseases of presumed immunopathogenesis. Hartung, H.P., Reiners, K., Schmidt, B., Stoll, G., Toyka, K.V. Ann. Neurol. (1991) [Pubmed]
  6. A human monoclonal anti-DNA antibody derived from a patient with polymyositis having the common lupus 16/6 idiotype. Shoenfeld, Y., Livne, A., Blank, M., Argov, S., Krup, M., Fleishmakher, E., Sukenik, S., Teplizki, H. Immunol. Lett. (1988) [Pubmed]
  7. Immunologic studies in cimetidine-induced nephropathy and polymyositis. Watson, A.J., Dalbow, M.H., Stachura, I., Fragola, J.A., Rubin, M.F., Watson, R.M., Bourke, E. N. Engl. J. Med. (1983) [Pubmed]
  8. Hepatitis B antigen and polymyositis. Mihas, A.A., Kirby, J.D., Kent, S.P. JAMA (1978) [Pubmed]
  9. Circulating autoantibody against human myoglobin in polymyositis. Nishikai, M., Homma, M. JAMA (1977) [Pubmed]
  10. Molecular characterization of an autoantigen of PM-Scl in the polymyositis/scleroderma overlap syndrome: a unique and complete human cDNA encoding an apparent 75-kD acidic protein of the nucleolar complex. Alderuccio, F., Chan, E.K., Tan, E.M. J. Exp. Med. (1991) [Pubmed]
  11. Cyclosporin for polymyositis. Bendtzen, K., Tvede, N., Andersen, V., Bendixen, G. Lancet (1984) [Pubmed]
  12. Cyclophosphamide in severe polymyositis. Bombardieri, S., Hughes, G.R., Neri, R., Del Bravo, P., Del Bono, L. Lancet (1989) [Pubmed]
  13. Polymyositis associated with simvastatin. Giordano, N., Senesi, M., Mattii, G., Battisti, E., Villanova, M., Gennari, C. Lancet (1997) [Pubmed]
  14. Creatine kinase MB isoenzyme in dermatomyositis: a noncardiac source. Larca, L.J., Coppola, J.T., Honig, S. Ann. Intern. Med. (1981) [Pubmed]
  15. Fatal polymyositis in D-penicillamine-treated rheumatoid arthritis. Doyle, D.R., McCurley, T.L., Sergent, J.S. Ann. Intern. Med. (1983) [Pubmed]
  16. The role of an autoantigen, histidyl-tRNA synthetase, in the induction and maintenance of autoimmunity. Miller, F.W., Waite, K.A., Biswas, T., Plotz, P.H. Proc. Natl. Acad. Sci. U.S.A. (1990) [Pubmed]
  17. Major histocompatibility complex genes in systemic lupus erythematosus, Sjögren's syndrome, and polymyositis. Arnett, F.C., Goldstein, R., Duvic, M., Reveille, J.D. Am. J. Med. (1988) [Pubmed]
  18. Cell-mediated immunity to myoglobin in polymyositis. Herrera-Esparza, R., Magaña, L., Moreno, J., Fraga, A., Lavalle, C. Ann. Rheum. Dis. (1983) [Pubmed]
  19. Novel autoantibodies to a voltage-gated potassium channel Kv1.4 in a severe form of myasthenia gravis. Suzuki, S., Satoh, T., Yasuoka, H., Hamaguchi, Y., Tanaka, K., Kawakami, Y., Suzuki, N., Kuwana, M. J. Neuroimmunol. (2005) [Pubmed]
  20. Progressive multifocal leukoencephalopathy in a patient with rheumatoid arthritis and polymyositis. Rankin, E., Scaravilli, F. J. Rheumatol. (1995) [Pubmed]
  21. Expression of immunoreactive major histocompatibility complex products in human skeletal muscles. Karpati, G., Pouliot, Y., Carpenter, S. Ann. Neurol. (1988) [Pubmed]
  22. A search for human T-cell leukemia virus type I in the lesions of patients with tropical spastic paraparesis and polymyositis. Tangy, F., Vernant, J.C., Coscoy, L., Ossondo, M., Bellance, R., Zaninovic, V., Cartier, L., Brahic, M., Ozden, S. Ann. Neurol. (1995) [Pubmed]
  23. Polymyositis, arthritis, and uveitis in a macaque experimentally infected with human T lymphotropic virus type I. Beilke, M.A., Traina-Dorge, V., England, J.D., Blanchard, J.L. Arthritis Rheum. (1996) [Pubmed]
  24. Anastomoses of transverse tubules with terminal cisternae in polymyositis. Chou, S.M., Nonaka, I., Voice, G.F. Arch. Neurol. (1980) [Pubmed]
  25. Kaposi's sarcoma in rheumatic diseases. Louthrenoo, W., Kasitanon, N., Mahanuphab, P., Bhoopat, L., Thongprasert, S. Semin. Arthritis Rheum. (2003) [Pubmed]
  26. Elevated serum levels of interleukin-1 receptor antagonist in polymyositis/dermatomyositis. A biologic marker of disease activity with a possible role in the lack of acute-phase protein response. Gabay, C., Gay-Croisier, F., Roux-Lombard, P., Meyer, O., Maineti, C., Guerne, P.A., Vischer, T., Dayer, J.M. Arthritis Rheum. (1994) [Pubmed]
  27. Autoantibodies to lipoprotein lipase and dyslipidemia in systemic lupus erythematosus. Reichlin, M., Fesmire, J., Quintero-Del-Rio, A.I., Wolfson-Reichlin, M. Arthritis Rheum. (2002) [Pubmed]
  28. Analysis of cytokine expression in muscle in inflammatory myopathies, Duchenne dystrophy, and non-weak controls. Lundberg, I., Brengman, J.M., Engel, A.G. J. Neuroimmunol. (1995) [Pubmed]
  29. Association of HLA class I and class II alleles with myositis in Japanese patients. Furuya, T., Hakoda, M., Higami, K., Ueda, H., Tsuchiya, N., Tokunaga, K., Kamatani, N., Kashiwazaki, S. J. Rheumatol. (1998) [Pubmed]
  30. Specific matrix metalloproteinase expression in focal myositis: an immunopathological study. Rodolico, C., Mazzeo, A., Toscano, A., Messina, S., Aguennouz, M., Gaeta, M., Messina, C., Vita, G. Acta neurologica Scandinavica. (2005) [Pubmed]
  31. Muscle fibres and cultured muscle cells express the B7.1/2-related inducible co-stimulatory molecule, ICOSL: implications for the pathogenesis of inflammatory myopathies. Wiendl, H., Mitsdoerffer, M., Schneider, D., Melms, A., Lochmuller, H., Hohlfeld, R., Weller, M. Brain (2003) [Pubmed]
  32. Radioimmunoassay of serum myoglobin in polymyositis and other conditions. Nishikai, M., Reichlin, M. Arthritis Rheum. (1977) [Pubmed]
  33. Pneumocystis carinii pneumonia in patients with connective tissue diseases: the role of hospital experience in diagnosis and mortality. Ward, M.M., Donald, F. Arthritis Rheum. (1999) [Pubmed]
  34. Clinical manifestations in patients with antibody to PL-12 antigen (alanyl-tRNA synthetase). Targoff, I.N., Arnett, F.C. Am. J. Med. (1990) [Pubmed]
  35. Prevalence and antigen specificity of anti-histone antibodies in patients with polymyositis/dermatomyositis. Kubo, M., Ihn, H., Yazawa, N., Sato, S., Kikuchi, K., Tamaki, K. J. Invest. Dermatol. (1999) [Pubmed]
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