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Gene Review

ARP4  -  actin-related protein 4

Arabidopsis thaliana

Synonyms: ATARP4, F15H18.8, F15H18_8
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Disease relevance of ATARP4

  • Phenotypic analysis of the arp4-1 mutant allele, which has a T-DNA insertion in the promoter region and a moderate reduction in the level of AtARP4 protein expression, revealed partial sterility due to defects in anther development [1].

High impact information on ATARP4


Biological context of ATARP4


Other interactions of ATARP4

  • Using isovariant-specific monoclonal antibodies, AtARP4 and AtARP7 proteins were shown to be most highly expressed in flowers [7].
  • This report shows that the use of live markers for actin visualisation may affect motility of cellular compounds and underlines the general need for critical investigation of actin-related processes in wild-type as well as transgenic plants prior to further interpretation [8].

Analytical, diagnostic and therapeutic context of ATARP4


  1. Silencing the nuclear actin-related protein AtARP4 in Arabidopsis has multiple effects on plant development, including early flowering and delayed floral senescence. Kandasamy, M.K., Deal, R.B., McKinney, E.C., Meagher, R.B. Plant J. (2005) [Pubmed]
  2. The nuclear actin-related protein ARP6 is a pleiotropic developmental regulator required for the maintenance of FLOWERING LOCUS C expression and repression of flowering in Arabidopsis. Deal, R.B., Kandasamy, M.K., McKinney, E.C., Meagher, R.B. Plant Cell (2005) [Pubmed]
  3. Mutations in actin-related proteins 2 and 3 affect cell shape development in Arabidopsis. Mathur, J., Mathur, N., Kernebeck, B., Hülskamp, M. Plant Cell (2003) [Pubmed]
  4. EARLY IN SHORT DAYS 1 (ESD1) encodes ACTIN-RELATED PROTEIN 6 (AtARP6), a putative component of chromatin remodelling complexes that positively regulates FLC accumulation in Arabidopsis. Martin-Trillo, M., Lázaro, A., Poethig, R.S., Gómez-Mena, C., Piñeiro, M.A., Martinez-Zapater, J.M., Jarillo, J.A. Development (2006) [Pubmed]
  5. Cell cycle-dependent association of Arabidopsis actin-related proteins AtARP4 and AtARP7 with the nucleus. Kandasamy, M.K., McKinney, E.C., Meagher, R.B. Plant J. (2003) [Pubmed]
  6. Breaking the WAVE complex: the point of Arabidopsis trichomes. Szymanski, D.B. Curr. Opin. Plant Biol. (2005) [Pubmed]
  7. Arabidopsis contains ancient classes of differentially expressed actin-related protein genes. McKinney, E.C., Kandasamy, M.K., Meagher, R.B. Plant Physiol. (2002) [Pubmed]
  8. Living markers for actin block myosin-dependent motility of plant organelles and auxin. Holweg, C.L. Cell Motil. Cytoskeleton (2007) [Pubmed]
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