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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Adenoma, Villous

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Disease relevance of Adenoma, Villous


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Chemical compound and disease context of Adenoma, Villous


Anatomical context of Adenoma, Villous


Gene context of Adenoma, Villous

  • It also remains unclear whether villous adenomas express cyclooxygenase-2 [15].
  • Here we examined secreted mucins in tubular, tubulovillous and villous adenomas of the rectum using non-VNTR antibodies designed to assess mature mucin [16].
  • Both CEA and SC expressions were found to be increased with the size of the adenomas, but only in the villous adenomas and not in the tubular adenomas [17].
  • There was a tendency toward a higher serum CEA level in patients with villous adenoma as compared with those with tubular structure [18].
  • A p53 gene mutation (GGC-->GAC at codon 245) was detected in two biopsies taken at a four year interval from a recurrent rectal villous adenoma [19].


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  2. APC mutations in human colorectal adenomas: analysis of the mutation cluster region with temperature gradient gel electrophoresis and clinicopathological features. Mulkens, J., Poncin, J., Arends, J.W., De Goeij, A.F. J. Pathol. (1998) [Pubmed]
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  5. Aberrant expression of a human mucin gene (MUC5AC) in rectosigmoid villous adenoma. Buisine, M.P., Janin, A., Maunoury, V., Audié, J.P., Delescaut, M.P., Copin, M.C., Colombel, J.F., Degand, P., Aubert, J.P., Porchet, N. Gastroenterology (1996) [Pubmed]
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  7. Cingulin, a specific protein component of tight junctions, is expressed in normal and neoplastic human epithelial tissues. Citi, S., Amorosi, A., Franconi, F., Giotti, A., Zampi, G. Am. J. Pathol. (1991) [Pubmed]
  8. Complete regression of villous adenomas of the colon using piroxicam, a nonsteroidal anti-inflammatory drug. Gowen, G.F. Dis. Colon Rectum (1996) [Pubmed]
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  11. Effect of cholesterol levels on villous histology in colonic adenomas. Houghton, J., Lardieri, G.G., Zauber, N.P., Kim, K.H., Cable, G. Dig. Dis. Sci. (2000) [Pubmed]
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  13. A study of ras gene mutations in colonic adenomas from familial polyposis coli patients. Farr, C.J., Marshall, C.J., Easty, D.J., Wright, N.A., Powell, S.C., Paraskeva, C. Oncogene (1988) [Pubmed]
  14. The glycosaminoglycans of the human colon in inflammatory and neoplastic conditions. Symonds, D.A. Arch. Pathol. Lab. Med. (1978) [Pubmed]
  15. Analysis of cyclooxygenase expression in human colorectal adenomas. Chapple, K.S., Scott, N., Guillou, P.J., Coletta, P.L., Hull, M.A. Dis. Colon Rectum (2002) [Pubmed]
  16. Abnormal subcellular distribution of mature MUC2 and de novo MUC5AC mucins in adenomas of the rectum: immunohistochemical detection using non-VNTR antibodies to MUC2 and MUC5AC peptide. Myerscough, N., Sylvester, P.A., Warren, B.F., Biddolph, S., Durdey, P., Thomas, M.G., Carlstedt, I., Corfield, A.P. Glycoconj. J. (2001) [Pubmed]
  17. The expression of carcinoembryonic antigen and secretory component in adenomas of the human colon and rectum. Griffioen, G., Bosman, F.T., Verspaget, H.W., de Bruin, P.A., Biemond, I., Lamers, C.B. Dis. Colon Rectum (1989) [Pubmed]
  18. Do size, histology, or cytology of colorectal adenomas and their removal influence serum CEA? Fischbach, W., Mössner, J. Dis. Colon Rectum (1987) [Pubmed]
  19. Genetic events in sporadic colorectal adenomas: K-ras and p53 heterozygous mutations are not sufficient for malignant progression. De Benedetti, L., Varesco, L., Pellegata, N.S., Losi, L., Gismondi, V., Casarino, L., Sciallero, S., Bonelli, L., Biticchi, R., Bafico, A. Anticancer Res. (1993) [Pubmed]
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