Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

MeSH Review:

Hyperostosis, Diffuse Idiopathic Skeletal

Resnick, D. et al., Altomonte, L. et al., Aceves-Avila, F.J. et al., Resnick, D. et al., Littlejohn, G.O. et al., et al.

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Hyperostosis, Diffuse Idiopathic Skeletal

Isotretinoin, a synthetic retinoid that has been prescribed for over 500,000 patients with cystic acne, has been associated with both spinal hyperostosis and a disorder similar to diffuse idiopathic skeletal hyperostosis [1].
Radiographic abnormalities of rheumatoid arthritis (RA) in 8 patients with diffuse idiopathic skeletal hyperostosis (DISH) included atypical features: lack of osteoporosis, bone sclerosis and proliferation about erosions, osteophytosis, and bony ankylosis [2].
Sesamoids may demonstrate osseous erosion in rheumatoid arthritis, bony proliferation or "whiskering" in rheumatoid variants, joint space narrowing and bony ankylosis in septic arthritis, and eburnation and osteophyte formation in osteoarthritis and diffuse idiopathic skeletal hyperostosis [3].
Marked hyperinsulinemia after glucose challenge in patients with diffuse idiopathic skeletal hyperostosis [4].
The occurrence of spinal fractures in ankylosing spondylitis is well documented but fractures are uncommon in patients with diffuse idiopathic skeletal hyperostosis (DISH) [5].

High impact information on Hyperostosis, Diffuse Idiopathic Skeletal

The association of ossification of the posterior longitudinal ligament (OPLL) and diffuse idiopathic skeletal hyperostosis (DISH) has been recently described [6].
Diffuse idiopathic skeletal hyperostosis of the cervical spine in a patient with ankylosing spondylitis [7].
Radiographic abnormalities of rheumatoid arthritis in patients with diffuse idiopathic skeletal hyperostosis [2].
Because of the increased prevalence of both vertebral ankylosing hyperostosis and HLA-B27 in Pima Indians, a possible association between the two was thought to exist [8].
Treatment with dapsone and etretinate was reasonably effective, but etretinate had to be discontinued due to the development of diffuse idiopathic skeletal hyperostosis [9].

Chemical compound and disease context of Hyperostosis, Diffuse Idiopathic Skeletal

The insulin response after a glucose challenge was studied in 11 male patients with diffuse idiopathic skeletal hyperostosis (DISH) and in 8 age, sex and weight matched controls [4].

Gene context of Hyperostosis, Diffuse Idiopathic Skeletal

STUDY DESIGN: Genetic screening of collagen 6A1 gene (COL6A1) in patients with diffuse idiopathic skeletal hyperostosis (DISH) recruited in Japan and the Czech Republic. OBJECTIVE: To investigate allelic associations between DISH and nucleotide variants of COL6A1 [10].
We found 19 cases of Pott's disease, 17 of osteoarthrosis in various anatomical locations, 2 spondyloarthropathies, probably ankylosing spondylitis or diffuse idiopathic skeletal hyperostosis, one probable septic arthritis in the stemoclavicular joint, and 2 compression fractures of the spine [11].
In patients with diffuse idiopathic skeletal hyperostosis (DISH), serum levels of insulin and GH were elevated, but IGF-1 levels were normal [12].
The association of HL-A B27 with Forestier's disease (vertebral ankylosing hyperostosis) [13].
Compression of the inferior vena cava due to diffuse idiopathic skeletal hyperostosis [14].

Analytical, diagnostic and therapeutic context of Hyperostosis, Diffuse Idiopathic Skeletal

Body mass index and blood glucose: correlations with serum insulin, growth hormone, and insulin-like growth factor-1 levels in patients with diffuse idiopathic skeletal hyperostosis (DISH) [15].
Serum insulin and C-peptide response to an oral glucose tolerance test (OGTT) and serum growth hormone (GH) response to an intravenous insulin tolerance test (IVITT) were investigated in six non-obese patients, with normal glucose tolerance, affected by diffuse idiopathic skeletal hyperostosis (DISH) [16].

References

Extraspinal tendon and ligament calcification associated with long-term therapy with etretinate. DiGiovanna, J.J., Helfgott, R.K., Gerber, L.H., Peck, G.L. N. Engl. J. Med. (1986) [Pubmed]
Radiographic abnormalities of rheumatoid arthritis in patients with diffuse idiopathic skeletal hyperostosis. Resnick, D., Curd, J., Shapiro, R.F., Wiesner, K.B. Arthritis Rheum. (1978) [Pubmed]
The sesamoid bones of the hands and feet: participators in arthritis. Resnick, D., Niwayama, G., Feingold, M.L. Radiology. (1977) [Pubmed]
Marked hyperinsulinemia after glucose challenge in patients with diffuse idiopathic skeletal hyperostosis. Littlejohn, G.O., Smythe, H.A. J. Rheumatol. (1981) [Pubmed]
Cervical spine fracture in diffuse idiopathic skeletal hyperostosis. Mody, G.M., Charles, R.W., Ranchod, H.A., Rubin, D.L. J. Rheumatol. (1988) [Pubmed]
Sudden quadriplegia complicating ossification of the posterior longitudinal ligament and diffuse idiopathic skeletal hyperostosis. Pouchot, J., Watts, C.S., Esdaile, J.M., Hill, R.O. Arthritis Rheum. (1987) [Pubmed]
Diffuse idiopathic skeletal hyperostosis of the cervical spine in a patient with ankylosing spondylitis. Williamson, P.K., Reginato, A.J. Arthritis Rheum. (1984) [Pubmed]
Vertebral ankylosing hyperostosis (Forestier's disease) and HLA antigens in Pima Indians. Spagnola, A.M., Bennett, P.H., Terasaki, P.I. Arthritis Rheum. (1978) [Pubmed]
Subcorneal pustular dermatosis and IgA paraproteinaemia: response to both etretinate and PUVA. Todd, D.J., Bingham, E.A., Walsh, M., Burrows, D. Br. J. Dermatol. (1991) [Pubmed]
COL6A1, the candidate gene for ossification of the posterior longitudinal ligament, is associated with diffuse idiopathic skeletal hyperostosis in Japanese. Tsukahara, S., Miyazawa, N., Akagawa, H., Forejtova, S., Pavelka, K., Tanaka, T., Toh, S., Tajima, A., Akiyama, I., Inoue, I. Spine. (2005) [Pubmed]
Paleopathology in osseous remains from the 16th century. A survey of rheumatic diseases. Aceves-Avila, F.J., Báez-Molgado, S., Medina, F., Fraga, A. J. Rheumatol. (1998) [Pubmed]
The role of growth factors in degenerative joint disorders. Moskowitz, R.W., Boja, B., Denko, C.W. The Journal of rheumatology. Supplement. (1991) [Pubmed]
The association of HL-A B27 with Forestier's disease (vertebral ankylosing hyperostosis). Shapiro, R.F., Utsinger, P.D., Wiesner, K.B., Resnick, D., Bryan, B.L., Castles, J.L. J. Rheumatol. (1976) [Pubmed]
Compression of the inferior vena cava due to diffuse idiopathic skeletal hyperostosis. Scapinelli, R. Revue du rhumatisme (English ed.) (1997) [Pubmed]
Body mass index and blood glucose: correlations with serum insulin, growth hormone, and insulin-like growth factor-1 levels in patients with diffuse idiopathic skeletal hyperostosis (DISH). Denko, C.W., Malemud, C.J. Rheumatol. Int. (2006) [Pubmed]
Growth hormone secretion in diffuse idiopathic skeletal hyperostosis. Altomonte, L., Zoli, A., Mirone, L., Marchese, G., Scolieri, P., Barini, A., Magarò, M. Ann. Ital. Med. Int. (1992) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.