Disease relevance of Fractures, Compression

• An asymptomatic vertebral spine compression fracture developed in 2 patients given prednisone; this was the only toxicity noted possibly due to this therapy [1].
• Estrogen and progesterone receptor-negative T11 vertebral hemangioma presenting as a postpartum compression fracture: case report and management [2].
• A young man hit by a car while riding his motorcycle presented with reversible hypotension, a compression fracture of C6, fractures of the left femur and of ribs 9-12 on the right, and right hemothorax [3].
• Nocturnal vertebral compression fractures may be the presenting feature of unwitnessed convulsive seizures, and evaluation for epilepsy should be considered in cases of idiopathic vertebral compression fractures [4].
• A high CsA trough level (between 147 and 225 ng/mL) over a period of only 5 months was effective in improving the vertebral compression fractures, alleviating the epidural lipomatosis by enabling the discontinuation of prednisolone treatment [5].

High impact information on Fractures, Compression

• Percutaneous vertebroplasty treatment of steroid-induced osteoporotic compression fractures [6].
• This report describes the case of a woman in whom multiple compression fractures of the lower thoracic and lumbar spine occurred in association with long-term corticosteroid therapy for systemic lupus erythematosus [6].
• Fractal geometry and vertebral compression fractures [7].
• Transiliac crest bone biopsies were obtained from 16 patients with osteoporosis and vertebral compression fractures (12 women and 4 men, mean age 56 years) before and after approximately 2 years of intermittent slow-release sodium fluoride therapy (25 mg twice a day) combined with continuous calcium citrate supplementation [8].
• Plasma vitamin D metabolites and parathyroid hormone concentrations of two groups of white women, aged 26-46 and 63-83 y, in Curaçao were studied to evaluate the effect of yearlong abundant sunlight on frequency of vertebral compression fractures in elderly women [9].

Chemical compound and disease context of Fractures, Compression

• Static and fatigue mechanical behavior of bone cement with elevated barium sulfate content for treatment of vertebral compression fractures [10].
• Alendronate (a bisphosphonate agent) has been shown to lower the prevalence of vertebral compression fractures and could potentially retard the collapse of an osteonecrotic femoral head [11].
• The maintenance of adequate disc height may allow the intervertebral discs to retain their discoid shape and viscoelastic function, containing vertical forces which may threaten spinal architecture leading to vertebral body compression fractures [12].
• We measured the hourly fractional rate of calcium absorption (alpha) with 45Ca and fasting urinary calcium/creatinine (Ca/Cr) and hydroxyproline/creatinine (OHPr/Cr) in 103 postmenopausal women aged 68 (0.67SE) years with vertebral compression fractures (77) or forearm or vertebral bone density below the young normal range (26) [13].
• Of the 5 patients with SSEL, 3 had vertebral compression fractures, and all 5 patients were on methylprednisolone pulse therapy [14].

Biological context of Fractures, Compression

• Forty-eight female patients with postmenopausal osteoporotic vertebral compression fractures were treated with sodium fluoride and calcium supplements; their response to treatment was documented by sequential measurements of vertebral and forearm bone mineral density (BMD) [15].
• To study the clinical significance of this observation, we examined the distribution of VDR genotypes in a subgroup of patients with severe osteoporosis who had vertebral compression fractures (n = 44) as compared with with age-and gender-matched controls (n = 44) [16].
• No significant relation to incidence and severity of vertebral body compression fractures, the Singh trabecular index, glomerular filtration rate, urinary calcium excretion, plasma levels of vitamin D, parathyroid hormone, or alkaline phosphatase was demonstrated [17].

Anatomical context of Fractures, Compression

• Although the scintigraphic photon-deficient area could not be differentiated due to the metastasis and the compression fracture, the abnormal radiocolloid findings of vertebrae may lead to further studies using Tc-99m diphosphonate, Ga-67, radiographic studies, and/or biopsy [18].
• Her symptoms abated when treated with prednisone, but she developed diabetes mellitus, osteoporosis, and compression fracture of lumbar vertebrae while being treated [19].
• A 10-year-old girl sustained hyperflexion injury to the midcervical spine, i.e., wedge compression fractures of the C3, C4, and C5 vertebral bodies, when hit by an automobile, subsequently manifesting central cord syndrome below the C4 spinal cord level [20].

Gene context of Fractures, Compression

• Our patient developed vertebral compression fractures at age 10, shortly after hypoparathyroidism was diagnosed [21].
• METHODS: A 69-year-old man with T12 osteoporotic compression fracture received percutaneous vertebroplasty [22].
• Two compression fractures were created in succession, the first in flexion preceded by a weakening defect in T3 and T10 and the second created in an adjacent vertebra in compression without prior weakening [23].
• Bone mineral density and vertebral compression fracture rates in ankylosing spondylitis [24].
• We reviewed the records of 2 patients with new onset of seizures seen at the Adult Epilepsy Clinic at the Henry Ford Hospital, Detroit, Mich, who had a history of vertebral compression fractures preceding the diagnosis of epilepsy [4].

Analytical, diagnostic and therapeutic context of Fractures, Compression

• Calcium phosphate cement-based vertebroplasty compared with conservative treatment for osteoporotic compression fractures: a matched case-control study [25].
• From April 1998 to January 2000 we treated 14 patients with vertebral osteoporotic compression fractures and intraosseous vacuum phenomenon with intracorporal bone grafting using a mixture of autogenous bone graft and calcium sulfate and posterior instrumentation [26].
• Injectable calcium phosphate bone cement Norian SRS for the treatment of intra-articular compression fractures of the distal radius in osteoporotic women [27].

References