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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Oval Window

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Disease relevance of Oval Window


High impact information on Oval Window


Anatomical context of Oval Window

  • METHODS: Using a variety of settings, a Sharplan 150 XJ Laser and a Contour model Erbium:YAG laser were applied to the oval window of human temporal bones [10].
  • New celluluar bone which simulated otosclerosis filled the anterior oval window niche and was continuous with the middle ear surface of the footplate fragments [11].
  • Gentamicin then penetrates the round and oval windows, where it influences inner ear function [12].
  • INTERVENTION: Analysis of perioperative and follow-up audiograms with associated operative findings, including obliterative otosclerosis and solid footplates, dehiscent or overhanging facial nerve, narrow oval window niche, promontory overhang, and ossicular fixation or malformation [13].
  • Subsequent tympanotomy confirmed the site of the CSF leak as the oval window in the majority of cases; packing the vestibule with muscle halted further attacks in these patients [14].

Associations of Oval Window with chemical compounds

  • The oval window niche was filled with either 1 percent sodium hyaluronate or 0.9 percent NaCl [15].
  • Then, DEM samples were mounted in oval windows equidistant between Ag/AgCl agar electrodes in exposure chambers containing serum-free medium [16].
  • Subsequent use of fluorescein intrathecally not only helped to confirm the diagnosis but was very useful at surgery in locating the leak in the dura of the oval window of the ear [17].

Gene context of Oval Window

  • Otosclerosis involved the left and right oval window niches (bilateral stapedectomy had been performed) [18].
  • The opercularis system (OPS) of amphibians consists of an opercularis muscle that connects the shoulder girdle skeleton to the operculum, a movable element in the oval window of the otic capsule [19].


  1. Recurrent meningitis secondary to idiopathic oval window CSF leak. Parisier, S.C., Birken, E.A. Laryngoscope (1976) [Pubmed]
  2. Perilymphatic fistula induced by barotrauma. Pullen, F.W. The American journal of otology. (1992) [Pubmed]
  3. Small fenestra stapedotomy using a fiberoptic hand-held argon laser in obliterative otosclerosis. Gherini, S.G., Horn, K.L., Bowman, C.A., Griffin, G. Laryngoscope (1990) [Pubmed]
  4. Otosclerotic obliteration of oval window niche: an analysis of the results of surgery. Gristwood, R.E., Venables, W.N. The Journal of laryngology and otology. (1975) [Pubmed]
  5. Retinoic acid disturbs mouse middle ear development in a stage-dependent fashion. Mallo, M. Dev. Biol. (1997) [Pubmed]
  6. Complicated cholesteatomas: CT findings in inner ear complications of middle ear cholesteatomas. Silver, A.J., Janecka, I., Wazen, J., Hilal, S.K., Rutledge, J.N. Radiology. (1987) [Pubmed]
  7. Neonatal deafening alters nonpyramidal dendrite orientation in auditory cortex: a computer microscope study in the rabbit. McMullen, N.T., Goldberger, B., Suter, C.M., Glaser, E.M. J. Comp. Neurol. (1988) [Pubmed]
  8. Congenital absence of the oval window: radiologic diagnosis and associated anomalies. Zeifer, B., Sabini, P., Sonne, J. AJNR. American journal of neuroradiology. (2000) [Pubmed]
  9. Cutaneous window for in vivo observations of organs and angiogenesis. Ciancio, S.J., Coburn, M., Hornsby, P.J. J. Surg. Res. (2000) [Pubmed]
  10. Photoacoustic effects of carbon dioxide lasers in stapes surgery: quantification in a temporal bone model. Gardner, E.K., Dornhoffer, J., Ferguson, S. Otol. Neurotol. (2002) [Pubmed]
  11. Nonotosclerotic ankylosis of the stapedial footplate. Adkins, W.Y., Gussen, R. South. Med. J. (1978) [Pubmed]
  12. Gentamicin and other ototoxic antibiotics for the transtympanic treatment of Menière's disease. Lange, G. Archives of oto-rhino-laryngology. (1989) [Pubmed]
  13. The other ear: findings and results in 1,800 bilateral stapedectomies. Daniels, R.L., Krieger, L.W., Lippy, W.H. Otol. Neurotol. (2001) [Pubmed]
  14. Recurrent meningitis in children due to inner ear abnormalities. Quiney, R.E., Mitchell, D.B., Djazeri, B., Evans, J.N. The Journal of laryngology and otology. (1989) [Pubmed]
  15. Sodium hyaluronate application to the open inner ear: an ultrastructural investigation. Bagger-Sjöbäck, D. The American journal of otology. (1991) [Pubmed]
  16. Electric fields and proliferation in a chronic wound model. Goldman, R., Pollack, S. Bioelectromagnetics. (1996) [Pubmed]
  17. Cerebrospinal otorrhea and recurring meningitis: report of three cases. Harris, H.H. Laryngoscope (1978) [Pubmed]
  18. Temporal bone showing polyarteritis nodosa, otosclerosis, and occult neuroma. Adkins, W.Y., Ward, P.H. Laryngoscope (1986) [Pubmed]
  19. Biomechanics of vibration reception in the bullfrog, Rana catesbeiana. Hetherington, T.E. J. Comp. Physiol. A (1988) [Pubmed]
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