Disease relevance of Hearing Loss, Conductive

• Treacher Collins syndrome (TCS) is an autosomal dominant disorder of craniofacial development, the features of which include conductive hearing loss and cleft palate [1].
• Mucin overproduction, a hallmark of both diseases, has been shown to directly cause conductive hearing loss in COME and airway obstruction in COPD [2].
• Several patients had poor surgical results, including recurrent conductive hearing loss, vertigo, and sensorineural hearing loss [3].
• Three patients had significant sensorineural hearing loss, two had conductive hearing loss and one patient had combined hearing loss [4].
• Of the 22 FAS patients, 17 (77%) had intermittent conductive hearing loss due to recurrent serous otitis media that persisted from early childhood into adulthood, whereas 6 (27%) had sensorineural hearing loss in addition to the conductive hearing loss [5].

High impact information on Hearing Loss, Conductive

• Treacher Collins syndrome (TCOF1) is an autosomal dominant disorder of craniofacial development the features of which include conductive hearing loss and cleft palate [6].
• Five of16 affected persons have surgically confirmed otosclerosis; the remaining nine have a conductive hearing loss but have not undergone corrective surgery [7].
• One hundred twenty-five children (aged 2.5 to 7 years) who met the usual indications for surgery (long-standing [greater than 3 months] OME and conductive hearing loss) were randomly assigned to "medical" treatment (sulfisoxazole 75 mg/kg per day for 6 months) or "surgical" treatment (bilateral insertion of VTs) [8].
• No other case of conductive hearing loss has previously been reported due to otoarthritis in ankylosing spondylitis [9].
• A monaural conductive hearing loss was induced by interrupting the chain of the middle ear ossicles on the right side in gerbils of four different age groups (P12-14, P20-21, P42 and P84) [10].

Chemical compound and disease context of Hearing Loss, Conductive

• The present investigation demonstrates the extent of a conductive loss caused by atresia and tests the hypothesis that GM1 ganglioside treatment will ameliorate the conductive hearing loss [11].
• The mean postoperative residual conductive hearing loss was smaller in the Nitinol group [12].
• An earlier study of ossiculoplasty showed that titanium prostheses were effective in reducing conductive hearing loss [13].
• A conductive hearing loss model was first developed in the cat using samarium cobalt as the target magnet [14].
• METHODS: In our research 40 patients with conductive hearing loss caused by otosclerosis underwent surgery with CO2 laser [15].

Biological context of Hearing Loss, Conductive

• A comparison was made between the Carhart-corrected bone conduction thresholds in 45 unoperated, non-noise-exposed individuals with stapedial otosclerosis and the thresholds in a matched random sample of the population with no conductive hearing loss [16].
• The subjects, who had various labyrinthine and retro-labyrinthine pathologies, included five patients with bilateral profound conductive hearing loss, two with bilateral acoustic neuroma post-total neurectomy and five with bilateral sensorineural hearing loss [17].
• The differential diagnosis of a non-effusion conductive hearing loss in a child should include otosclerosis, congenital malleus or footplate fixation, tympanosclerotic fixation, congenital cholesteatoma, lysis of the incus long process, Paget's disease, osteogenesis imperfecta, and fibromuscular hyperplasia of the renal artery [18].

Anatomical context of Hearing Loss, Conductive

• The cause of conductive hearing loss and peripheral sensorineural hearing loss was usually identified by the type of temporal bone fracture [19].
• This patient also had some minor oral-facial anomalies, severe nonfamilial myopia, bilateral conductive hearing loss, ureteric reflux, and skeletal anomalies other than those noted in the skull and upper limbs [20].
• Sensorineural and conductive hearing loss associated with lateral semicircular canal malformation [21].
• The study included 129 eardrums of 79 subjects that were divided into 3 groups: 1) normal subjects and 2) patients with sensorineural and 3) conductive hearing loss (HL) [22].
• CONCLUSION: In patients with cleidocranial dysplasia, eustachian tube dysfunction, conductive hearing loss, and sensorineural hearing loss are common because of structural and functional changes of the temporal bone and palate [23].

Gene context of Hearing Loss, Conductive

• One of these, Treacher Collins syndrome (TCOF1), is an autosomal dominant disorder of craniofacial development the features of which include conductive hearing loss and cleft palate [24].
• Treacher Collins syndrome (TCS) is an autosomal dominant disorder of craniofacial development, the features of which include conductive hearing loss and cleft palate [25].
• Treacher Collins syndrome is an autosomal dominant disorder of craniofacial development, the features of which include conductive hearing loss and cleft palate [26].
• Manifestations include: VSD and ASD, mild developmental delay, conductive hearing loss, minor facial anomalies, thrombocytopenia, and radiological findings (including carpal fusion) [27].
• Masker interaural phase and the MLD: effects of conductive hearing loss [28].

Analytical, diagnostic and therapeutic context of Hearing Loss, Conductive

• OBJECTIVE/HYPOTHESIS: To compare the effectiveness and long-term stability of hearing results between stapedectomy and small fenestra stapedotomy in patients with conductive hearing loss due to otosclerosis [29].
• Twelve percent of the patients had tinnitus following surgery and 5% required a hearing aid as a result of a combined sensorineural and conductive hearing loss which occurred in their better hearing ear as a result of surgery [30].
• Animal models of conductive hearing loss (CHL) show altered structure and function in the central auditory system (CAS), particularly following unilateral deprivation [31].
• Delta 1 and delta f repetitive stimuli superimposed on continuous 0.5-, 1- and 4-kHz carrier tones were administered to 20 normally hearing persons, 8 adults with sensorineural hearing loss, 10 adults with conductive hearing loss and 22 children subjected to evoked response audiometry (ERA) for assessment of hearing acuity [32].
• A conductive hearing loss that was statistically significant (p < .05) at 250 Hz, 500 Hz, 1 kHz, and 2 kHz in the right and left ears was found in 17.14% of the RA patients and in 5.71% of the control group [33].

References