Disease relevance of Cerclage, Cervical

• Exclusion criteria were: previous preterm delivery, or mid-trimester abortion or termination of pregnancy, multiple gestation, oligo- or polyhydramnios, placenta previa, fetal abnormalities, uterine malformations, cervical incompetence, cervical cerclage, or receipt of an antibiotic effective against BV or GBS following the screening [1].

High impact information on Cerclage, Cervical

• Extremely prolonged unilateral block (20 hours) with spinal ropivacaine used for cervical cerclage placement [2].
• Subarachnoid small-dose bupivacaine versus lidocaine for cervical cerclage [3].
• IMPLICATIONS: We found that small-dose subarachnoid bupivacaine (5.25 mg) with fentanyl 20 micro g provides reliable anesthesia for cervical cerclage and exhibits a pharmacodynamic profile similar to that of small-dose lidocaine [3].
• Vaginal fetal fibronectin as a predictor of spontaneous preterm delivery in the patient with cervical cerclage [4].
• Final report of the MRC/RCOG randomised controlled trial of cervical cerclage [5].

Biological context of Cerclage, Cervical

• OBJECTIVE: To investigate the effect of surgical procedures at 15 weeks gestation (amniocentesis or cervical cerclage), with or without post-operative ritodrine prophylaxis, on uterine blood flow velocity waveforms and maternal heart rate [6].
• CONCLUSION: A preoperative CRP value </=4.0 mg/dl, a WBC count </=14,000/ microl, and cervical dilatation </=4.0 cm were significantly associated with prolongation of pregnancy after emergency cervical cerclage [7].

Anatomical context of Cerclage, Cervical

• Patients with a markedly effaced or dilated cervix and protruding membranes between 21 and 26 weeks' gestation were managed by Shirodkar cervical cerclage, perioperative tocolysis, broad-spectrum antibiotic therapy, and, in selected cases, inhibition of prostaglandin synthesis with indomethacin [8].

Associations of Cerclage, Cervical with chemical compounds

• Plasma concentrations of prostaglandin F2 alpha and prostaglandin E2 metabolites after transabdominal and transvaginal cervical cerclage [9].
• RESULTS: The only statistically significant difference in haemodynamic values between those obtained before the procedure and those obtained after the procedure with or without prophylactic ritodrine was seen in the women who had cervical cerclage with postoperative intravenous ritodrine [6].
• RESULTS: The 22 patients that were treated with cervical cerclage were not significantly different from the 21 given expectant management in ethnic origin, ponderal index, cigarette smoking or past obstetric history [10].
• It is our view that transabdominal cervical cerclage should only be performed in units that have specialists in Perinatal Medicine [11].
• Non-surgical methods including systemic methotrexate administration in one and surgical evacuation of products of conception with subsequent cervical cerclage in another are discussed [12].

Gene context of Cerclage, Cervical

• OBJECTIVE: To assess the relation between the preoperative serum level of C-reactive protein (CRP) and the WBC count and the efficacy of emergency cervical cerclage [7].

Analytical, diagnostic and therapeutic context of Cerclage, Cervical

• Plasma prostaglandin metabolites, prostaglandin F1a (PGF1a) and prostaglandin E2 (PGE2) were measured in a serial set of maternal serum samples by radioimmunoassay after elective transvaginal cervical cerclage (Shirodkar) in 18 patients early in the 2nd trimester (14-15 weeks of gestation) for a history of cervical incompetence [13].

References