Disease relevance of Cholecystolithiasis

• This report describes five patients with cholecystolithiasis and choledocholithiasis who were treated by combination endoscopic extraction of common bile-duct stones with sphincterotomy (EST) and laparoscopic cholecystectomy (LC) [1].
• The number and adhering activity of CR1 in patients with chronic cholecystitis and cholecystolithiasis (1.078+/-0.21, 55.1+/-5.9) were significantly lower than those in healthy controls (1.252+/-0.31, 64.2+/-7.4) (P<0.05) [2].
• Ascending colon cancer with hepatic metastasis and cholecystolithiasis in a patient with situs inversus totalis without any expression of UVRAG mRNA: report of a case [3].

High impact information on Cholecystolithiasis

• In 1966, during cholecystectomy for cholecystolithiasis, a 56-year-old man was found to have islet-cell carcinoma metastatic to the liver; his fasting serum glucose level was normal [4].
• CONCLUSIONS: This striking effect of CCK 27-33 in the sub-contractor group favors the view of CCK-receptor structural alteration in a subgroup of patients with cholecystolithiasis [5].
• These results suggest the importance of cholecystolithiasis, especially that of the cholesterol stones, as a background factor of gallbladder carcinoma [6].
• CONCLUSION: Our data indicate that TGF-beta and CTGF are involved in ultrastructural tissue changes in patients with cholecystolithiasis [7].
• In the present study we analyzed the role of TGF-beta and its downstream target CTGF in patients with cholecystolithiasis [7].

Chemical compound and disease context of Cholecystolithiasis

• This study presents cholesterol and DNA contents of arterial tissue from biopsies of the cystic artery in 23 patients with uncomplicated cholecystolithiasis [8].
• Gallbladder stones (GBS) are found in up to 50% of patients receiving octreotide, but the reported prevalence of cholecystolithiasis in patients treated with octreotide is variable and little is known about gallstone incidence, composition, pathogenetic mechanisms, dissolvability, and primary prevention [9].
• Fundal or diffuse adenomyomatosis appears to be unrelated to cholecystolithiasis [10].

Anatomical context of Cholecystolithiasis

• Elevated cholecystokinin-like activity in the duodenal mucosa in patients with cholecystolithiasis [11].
• The tumor was incidentally identified in a 77-year-old Japanese man with cholecystolithiasis, hepatocellular carcinoma and sigmoid colon carcinoma [12].
• Antileukoprotease, an inhibitor of granulocyte elastase, was studied in paired sera from 19 patients with pneumonia and from 9 patients with cholecystolithiasis [13].

Gene context of Cholecystolithiasis

• One subject of EA2 had cholecystolithiasis and another one renal redoublication [14].
• RESULTS: The levels of CD62P, CD63 in patients with hepatolithiasis were higher than those in patients with cholecystolithiasis (P<0.05), but the count of platelets was lower (P<0.05) [15].
• Levels of carcinoembryonic antigen (CEA) in gallbladder bile were determined in 36 patients with cholecystolithiasis, some of whom showed extremely high values [16].

Analytical, diagnostic and therapeutic context of Cholecystolithiasis

• RESULTS: By northern blot analysis there was an enhanced TGF-beta1 mRNA expression (eightfold increase; P < 0.04) in the cholecystolithiasis tissue samples in comparison with normal controls [7].
• Cholecystokinin (CCK)-like activities in the duodenal mucosa of the patients with cholecystolithiasis were determined with the bioassay method we established [11].

References