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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Forensic Sciences

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High impact information on Forensic Sciences

  • A number of applications of analysis of human Y-chromosome microsatellite loci to human evolution and forensic science require reliable estimates of the mutation rate and knowledge of the mutational mechanism [1].
  • Systematic errors of this type were not found using the interim ceiling principle recently advocated in the National Research Council's report [National Research Council (1992) DNA Technology in Forensic Science (Natl. Acad. Sci., Washington)] [2].
  • In this paper, we compare the ABI Prism 377 slab-gel sequencer currently used by the Forensic Science Service with three leading capillary array electrophoresis instruments: the ABI Prism 3700, the Amersham MegaBACE 1000 and the 16-capillary ABI Prism 3100 [3].
  • A new multiplex PCR system, developed by the Forensic Science Service (FSS) in the United Kingdom, permits the coamplification and typing of six short tandem repeat (STR) loci: HUMFGA, D8S1179, HUMTHO1, HUMvWA, D18S51, D21S11 and the sex determining marker Amelogenin [4].
  • All three isozymes show genetic variation, and PGM1 has achieved prominence as a key marker in genetic linkage mapping and in forensic science [5].

Biological context of Forensic Sciences


Associations of Forensic Sciences with chemical compounds


Gene context of Forensic Sciences

  • This Se genotyping system is a simple method available for the forensic science field in Japan. The crossover region of the se(fus) gene is a 164-bp stretch corresponding to the regions between the 253rd and 416th of the Sec1 gene and between the 211th and 374th of the Sec2 gene [13].
  • The future of forensic and crime scene science. Part I. A UK forensic science user and provider perspective [14].
  • Commentary on: Mark Benecke and Larry Barksdale, Distinction of bloodstain patterns from fly artifacts. Forensic Science International. 137(2003) 152-159 [15].
  • Keratin characterization through electrophoretic techniques has been used for species identification in forensic science and in taxonomic studies [16].
  • Currently, optical devices, such as microscopes and CCD cameras, are utilized for identification of bullets and tool marks in the field of forensic science [17].

Analytical, diagnostic and therapeutic context of Forensic Sciences


  1. Characteristics and frequency of germline mutations at microsatellite loci from the human Y chromosome, as revealed by direct observation in father/son pairs. Kayser, M., Roewer, L., Hedman, M., Henke, L., Henke, J., Brauer, S., Krüger, C., Krawczak, M., Nagy, M., Dobosz, T., Szibor, R., de Knijff, P., Stoneking, M., Sajantila, A. Am. J. Hum. Genet. (2000) [Pubmed]
  2. Genetic differences at four DNA typing loci in Finnish, Italian, and mixed Caucasian populations. Krane, D.E., Allen, R.W., Sawyer, S.A., Petrov, D.A., Hartl, D.L. Proc. Natl. Acad. Sci. U.S.A. (1992) [Pubmed]
  3. Evaluation and validation of the ABI 3700, ABI 3100, and the MegaBACE 1000 capillary array electrophoresis instruments for use with short tandem repeat microsatellite typing in a forensic environment. Koumi, P., Green, H.E., Hartley, S., Jordan, D., Lahec, S., Livett, R.J., Tsang, K.W., Ward, D.M. Electrophoresis (2004) [Pubmed]
  4. Genetic diversity at six short tandem repeat loci within the state of Victoria, Australia. Wilson-Wilde, L.M., van Oorschot, R.A., Mitchell, R.J. Electrophoresis (1997) [Pubmed]
  5. A novel human phosphoglucomutase (PGM5) maps to the centromeric region of chromosome 9. Edwards, Y.H., Putt, W., Fox, M., Ives, J.H. Genomics (1995) [Pubmed]
  6. A new alpha 2HS-glycoprotein typing by isoelectric focusing. Umetsu, K., Kashimura, S., Ikeda, N., Suzuki, T. Hum. Genet. (1984) [Pubmed]
  7. Genetic polymorphism of human C1R subcomponent of the first complement component in the Japanese population. Nakamura, S., Ohue, O., Akiyama, K., Abe, K. Forensic Sci. Int. (1988) [Pubmed]
  8. The role of ethanol abuse in the etiology of heroin-related death. Ruttenber, A.J., Kalter, H.D., Santinga, P. J. Forensic Sci. (1990) [Pubmed]
  9. The content of ecstasy tablets: implications for the study of their long-term effects. Cole, J.C., Bailey, M., Sumnall, H.R., Wagstaff, G.F., King, L.A. Addiction (2002) [Pubmed]
  10. DNA analysis in the case of Kaspar Hauser. Weichhold, G.M., Bark, J.E., Korte, W., Eisenmenger, W., Sullivan, K.M. Int. J. Legal Med. (1998) [Pubmed]
  11. Assessment of UDP-glucuronosyltransferase catalyzed formation of ethyl glucuronide in human liver microsomes and recombinant UGTs. Foti, R.S., Fisher, M.B. Forensic Sci. Int. (2005) [Pubmed]
  12. PCR-VNTRs (PCR-Variable Number of Tandem Repeats) in forensic science. Möller, A., Brinkmann, B. Cell. Mol. Biol. (Noisy-le-grand) (1995) [Pubmed]
  13. Se genotyping following allele-specific polymerase chain reaction amplification. Mitani, T., Tsujita, H., Sonoda, S., Akane, A. Legal medicine (Tokyo, Japan) (2002) [Pubmed]
  14. The future of forensic and crime scene science. Part I. A UK forensic science user and provider perspective. Mennell, J., Shaw, I. Forensic Sci. Int. (2006) [Pubmed]
  15. Commentary on: Mark Benecke and Larry Barksdale, Distinction of bloodstain patterns from fly artifacts. Forensic Science International. 137(2003) 152-159. Ristenbatt, R.R., Pizzola, P.A., Shaler, R.C., Sorkin, L.N. Forensic Sci. Int. (2005) [Pubmed]
  16. Electrophoretic analysis of non-human primates hair keratin. Folin, M., Contiero, E. Forensic Sci. Int. (1996) [Pubmed]
  17. Three dimensional visualization and comparison of impressions on fired bullets. Banno, A., Masuda, T., Ikeuchi, K. Forensic Sci. Int. (2004) [Pubmed]
  18. The use of capillary electrophoresis in the detection of monomethylamine and benzoate ions in the forensic examination of explosives residues. Klapec, D.J., Ng, D. J. Forensic Sci. (2001) [Pubmed]
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