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MeSH Review


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Disease relevance of Andropause


Psychiatry related information on Andropause


High impact information on Andropause


Biological context of Andropause


Associations of Andropause with chemical compounds


Gene context of Andropause

  • Therefore, it is not surprising that the dysregulation of the HPG axis with menopause and andropause (leading to elevated LH, GnRH, and activin signaling but decreased sex steroid signaling) might promote alterations in both the structure and function of neuronal cells [19].
  • The controversies in evaluating gonadal function are illustrated by the andropause (elevated SHBG) and obese men (decreased SHBG) [20].
  • No major month to month variation in free testosterone levels in aging males. Minor impact on the biological diagnosis of 'andropause' [21].
  • The role of nuclear transcription factors (androgen receptor and any other transacting factor(s) which may be involved) in the coordinate regulation of alpha 2u-globulin and SMP-2 during aging and nutritional manipulation is being explored to establish the molecular mechanism of andropause in the liver [22].
  • ADAM and the andropause [23].


  1. Androgenic regulation of oxidative stress in the rat prostate: involvement of NAD(P)H oxidases and antioxidant defense machinery during prostatic involution and regrowth. Tam, N.N., Gao, Y., Leung, Y.K., Ho, S.M. Am. J. Pathol. (2003) [Pubmed]
  2. Andropause. Vance, M.L. Growth Horm. IGF Res. (2003) [Pubmed]
  3. Somatopause: dismetabolic and bone effects. Lombardi, G., Tauchmanova, L., Di Somma, C., Musella, T., Rota, F., Savanelli, M.C., Colao, A. J. Endocrinol. Invest. (2005) [Pubmed]
  4. Male hypogonadism : an update on diagnosis and treatment. Darby, E., Anawalt, B.D. Treatments in endocrinology. (2005) [Pubmed]
  5. Memory loss as a reported symptom of andropause. Tan, R.S. Arch. Androl. (2001) [Pubmed]
  6. The andropause and memory loss: is there a link between androgen decline and dementia in the aging male? Tan, R.S., Pu, S.J. Asian J. Androl. (2001) [Pubmed]
  7. Chemical andropause and amyloid-beta peptide. Gandy, S., Almeida, O.P., Fonte, J., Lim, D., Waterrus, A., Spry, N., Flicker, L., Martins, R.N. JAMA (2001) [Pubmed]
  8. Andropause: is androgen replacement therapy indicated for the aging male? Hijazi, R.A., Cunningham, G.R. Annu. Rev. Med. (2005) [Pubmed]
  9. Age-associated increased interleukin-6 gene expression, late-life diseases, and frailty. Ershler, W.B., Keller, E.T. Annu. Rev. Med. (2000) [Pubmed]
  10. Luteinizing hormone, a reproductive regulator that modulates the processing of amyloid-beta precursor protein and amyloid-beta deposition. Bowen, R.L., Verdile, G., Liu, T., Parlow, A.F., Perry, G., Smith, M.A., Martins, R.N., Atwood, C.S. J. Biol. Chem. (2004) [Pubmed]
  11. Increased carotid atherosclerosis in andropausal middle-aged men. Mäkinen, J., Järvisalo, M.J., Pöllänen, P., Perheentupa, A., Irjala, K., Koskenvuo, M., Mäkinen, J., Huhtaniemi, I., Raitakari, O.T. J. Am. Coll. Cardiol. (2005) [Pubmed]
  12. Climacteric medicine: European Menopause and Andropause Society (EMAS) 2004/2005 position statements on peri- and postmenopausal hormone replacement therapy. Skouby, S.O., Al-Azzawi, F., Barlow, D., Calaf-Alsina Erdogan Ertüngealp, J., Gompel, A., Graziottin, A., Hudita, D., Pines, A., Rozenberg, S., Samsioe, G., Stevenson, J.C. Maturitas. (2005) [Pubmed]
  13. Recent advances in clinical/molecular andrology. Hafez, B. Arch. Androl. (1998) [Pubmed]
  14. Age-associated testosterone decline in men: clinical issues for psychiatry. Sternbach, H. The American journal of psychiatry. (1998) [Pubmed]
  15. Should the nonaromatizable androgen dihydrotestosterone be considered as an alternative to testosterone in the treatment of the andropause? Wang, C., Swerdloff, R.S. J. Clin. Endocrinol. Metab. (2002) [Pubmed]
  16. Soy isoflavone phyto-pharmaceuticals in interleukin-6 affections. Multi-purpose nutraceuticals at the crossroad of hormone replacement, anti-cancer and anti-inflammatory therapy. Dijsselbloem, N., Vanden Berghe, W., De Naeyer, A., Haegeman, G. Biochem. Pharmacol. (2004) [Pubmed]
  17. Use of clomiphene citrate to reverse premature andropause secondary to steroid abuse. Tan, R.S., Vasudevan, D. Fertil. Steril. (2003) [Pubmed]
  18. Estrogen bows to a new master: the role of gonadotropins in Alzheimer pathogenesis. Webber, K.M., Casadesus, G., Marlatt, M.W., Perry, G., Hamlin, C.R., Atwood, C.S., Bowen, R.L., Smith, M.A. Ann. N. Y. Acad. Sci. (2005) [Pubmed]
  19. The gonadotropin connection in Alzheimer's disease. Meethal, S.V., Smith, M.A., Bowen, R.L., Atwood, C.S. Endocrine (2005) [Pubmed]
  20. Current controversies in testosterone testing: aging and obesity. Elin, R.J., Winters, S.J. Clin. Lab. Med. (2004) [Pubmed]
  21. No major month to month variation in free testosterone levels in aging males. Minor impact on the biological diagnosis of 'andropause'. Tancredi, A., Reginster, J.Y., Luyckx, F., Legros, J.J. Psychoneuroendocrinology (2005) [Pubmed]
  22. Changes in hepatic androgen sensitivity and gene expression during aging. Chatterjee, B., Roy, A.K. J. Steroid Biochem. Mol. Biol. (1990) [Pubmed]
  23. ADAM and the andropause. Wyllie, M.G. BJU international. (2003) [Pubmed]
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