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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Elbow Joint

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Disease relevance of Elbow Joint


High impact information on Elbow Joint

  • 1. Reflex activity in human arm muscles has been measured in response to torque perturbations around the elbow joint in the flexion-extension direction and/or the supination-pronation direction [6].
  • OBJECTIVES: Open synovectomy of the elbow joint is often performed in early stages of rheumatoid arthritis [7].
  • Electromyograms were recorded by surface electrodes from the mm. biceps brachii (caput longum et breve), brachioradialis and triceps brachii (caput longum) in 10 healthy human subjects during slow linear movements in the elbow joint against a weak extending torque [8].
  • 4. Torque and angle responses recorded during stochastic perturbations were used to identify elbow joint compliance impulse responses [9].
  • Thus flexor and extensor muscles of wrist and elbow joints are reflexly coactivated by the impact of a ball on the hand during a catching task [10].

Biological context of Elbow Joint

  • 2. A bout of 70 maximum voluntary eccentric muscle actions performed with the forearm flexors elicited delayed muscle soreness, efflux of creatine kinase into the blood, loss of elbow joint range of motion and a prolonged decline in maximum voluntary isometric contraction torque at the three elbow angles monitored (P < 0.01) in 30 subjects [11].

Anatomical context of Elbow Joint


Associations of Elbow Joint with chemical compounds

  • Maximal isometric force, relaxed and flexed elbow joint angle, muscle soreness, plasma creatine kinase, and glutamic-oxaloacetic transaminase activities were assessed [15].
  • In this paper, a geometric model of the anatomical elbow joint in the coronal plane is described [16].
  • The supracondylar fracture of the humerus is one of the most common in children, approximately one hundred per year, in Kuwait. The treatment consists in manipulation and fixation by plaster of Paris in the most stable position, usually maximal possible flexion in the elbow joint [17].
  • "Latent" dislocation of the elbow joint. A factor in seemingly inexplicable post-traumatic stiffness [18].
  • (3) Hydroxyproline/creatinine ratio in the group with pain in the hands or with motility disturbance in the elbow joints was significantly higher than that in the group without them (p less than 0.05) [19].

Gene context of Elbow Joint

  • As early as 4 h after injection, the anti-human CD4 MAb showed a higher target-to-background ratio in arthritic knee and elbow joints in comparison to polyclonal HIG used for conventional imaging, indicating that that anti-CD4 MAb allows more specific detection of inflammatory infiltrates rich in CD4-positive cells [20].
  • METHODS: Fifteen subjects performed three sets of 10 repetitions of eccentric training (ECC-T) with one arm and concentric training (CON-T) with the other arm once a week for 8 wk using a dumbbell representing 50% of maximal isometric force of the elbow flexors (MIF) determined at the elbow joint of 90 degrees (1.57 rad) [21].
  • RESULTS: A statistically significant association between HFE mutations and OA was observed for the MCP2,3 joints (p = 0.0001) and the ankle/IT/TMT joint group (p = 0.002) as well as for the 3 joint regions collectively (p = 0.0001), but not for the elbow joints (p = 0.062) [22].
  • Cutting of the LCLC at the ulnar or the humeral insertion was necessary for any PST stressed elbow joint laxity to occur [23].
  • Maximal isometric strength, flexed and relaxed elbow joint angles, range of motion, upper arm circumference, muscle soreness, plasma creatine kinase (CK), and myoglobin (Mb) were measured before, immediately after, and for 4 days after exercise [24].

Analytical, diagnostic and therapeutic context of Elbow Joint


  1. MR arthrography of the elbow: normal anatomy and diagnostic pitfalls. Cotten, A., Jacobson, J., Brossmann, J., Hodler, J., Trudell, D., Resnick, D. Journal of computer assisted tomography. (1997) [Pubmed]
  2. Posterior interosseous nerve syndrome associated with rheumatoid synovial cysts of the elbow joint. Ishikawa, H., Hirohata, K. Clin. Orthop. Relat. Res. (1990) [Pubmed]
  3. Antley-Bixler syndrome: a disorder characterized by congenital synostosis of the elbow joint and the cranial suture. Kitoh, H., Nogami, H., Oki, T., Arao, K., Nagasaka, M., Tanaka, Y. Journal of pediatric orthopedics. (1996) [Pubmed]
  4. Diagnostic and therapeutic injection of the elbow region. Cardone, D.A., Tallia, A.F. American family physician. (2002) [Pubmed]
  5. Popliteal pterygium syndrome with unusual features. Sasidharan, C.K., Ravi, K.V. Indian journal of pediatrics. (2004) [Pubmed]
  6. Long-latency stretch reflexes as co-ordinated functional responses in man. Gielen, C.C., Ramaekers, L., van Zuylen, E.J. J. Physiol. (Lond.) (1988) [Pubmed]
  7. Influence of previous open synovectomy on the outcome of Souter-Strathclyde total elbow prosthesis. van der Lugt, J.C., Geskus, R.B., Rozing, P.M. Rheumatology (Oxford, England) (2004) [Pubmed]
  8. Analysis of the electromyographic activity of human elbow joint muscles during slow linear flexion movements in isotorque conditions. Tal'nov, A.N., Serenko, S.G., Strafun, S.S., Kostyukov, A.I. Neuroscience (1999) [Pubmed]
  9. Neural compensation for fatigue-induced changes in muscle stiffness during perturbations of elbow angle in human. Kirsch, R.F., Rymer, W.Z. J. Neurophysiol. (1992) [Pubmed]
  10. Transient reversal of the stretch reflex in human arm muscles. Lacquaniti, F., Borghese, N.A., Carrozzo, M. J. Neurophysiol. (1991) [Pubmed]
  11. Length-specific impairment of skeletal muscle contractile function after eccentric muscle actions in man. Saxton, J.M., Donnelly, A.E. Clin. Sci. (1996) [Pubmed]
  12. Differential distribution of interneurons in the neural networks that control walking in the mudpuppy (Necturus maculatus) spinal cord. Cheng, J., Jovanovic, K., Aoyagi, Y., Bennett, D.J., Han, Y., Stein, R.B. Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale. (2002) [Pubmed]
  13. Thorotrast-induced hepatic angiosarcoma with 39 years latency. A pathologic and immunohistochemical study. Abe, M., Wakasa, H. Acta Pathol. Jpn. (1987) [Pubmed]
  14. A review of total elbow arthroplasty and an early assessment of the Liverpool elbow prosthesis. Sourmelis, S.G., Burke, F.D., Varian, J.P. Journal of hand surgery (Edinburgh, Lothian) (1986) [Pubmed]
  15. Muscle damage following repeated bouts of high force eccentric exercise. Nosaka, K., Clarkson, P.M. Medicine and science in sports and exercise. (1995) [Pubmed]
  16. The relationship between surface topography and contact in the elbow joint: development of a two-dimensional geometrical model in the coronal plane. Waide, D.V., Lawlor, G.J., McCormack, B.A., Carr, A.J. Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine. (2000) [Pubmed]
  17. Supracondylar fracture of the humerus in children--closed pinning. Rejholec, M. Sborník lékar̆ský. (1999) [Pubmed]
  18. "Latent" dislocation of the elbow joint. A factor in seemingly inexplicable post-traumatic stiffness. Garden, J., Miller, J.H. Acta orthopaedica Belgica. (1975) [Pubmed]
  19. Urinary excretion of hydroxyproline in workers occupationally exposed to vibration. Kasamatsu, T., Miyashita, K., Shiomi, S., Iwata, H. British journal of industrial medicine. (1982) [Pubmed]
  20. Comparison of 99Tcm-labelled specific murine anti-CD4 monoclonal antibodies and nonspecific human immunoglobulin for imaging inflamed joints in rheumatoid arthritis. Kinne, R.W., Becker, W., Schwab, J., Horneff, G., Schwarz, A., Kalden, J.R., Emmrich, F., Burmester, G.R., Wolf, F. Nuclear medicine communications. (1993) [Pubmed]
  21. Concentric or eccentric training effect on eccentric exercise-induced muscle damage. Nosaka, K., Newton, M. Medicine and science in sports and exercise. (2002) [Pubmed]
  22. HFE gene mutations are associated with osteoarthritis in the index or middle finger metacarpophalangeal joints. Carroll, G.J. J. Rheumatol. (2006) [Pubmed]
  23. Posterolateral elbow joint instability: the basic kinematics. Olsen, B.S., Søjbjerg, J.O., Nielsen, K.K., Vaesel, M.T., Dalstra, M., Sneppen, O. Journal of shoulder and elbow surgery / American Shoulder and Elbow Surgeons ... [et al.]. (1998) [Pubmed]
  24. Attenuation of protective effect against eccentric exercise-induced muscle damage. Nosaka, K., Newton, M.J., Sacco, P. Canadian journal of applied physiology = Revue canadienne de physiologie appliquée. (2005) [Pubmed]
  25. Total elbow joint arthroplasty in patients with rheumatoid arthritis. Pritchard, R.W. Semin. Arthritis Rheum. (1991) [Pubmed]
  26. Relationship between clinically detected joint swelling and effusion diagnosed by ultrasonography in elbow joints in patients with rheumatoid arthritis. Luukkainen, R., Sanila, M.T., Saltyshev, M., Huhtala, H., Koski, J.M. Clin. Rheumatol. (2005) [Pubmed]
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