Disease relevance of calcium sulfate

• Treatment of unicameral bone cysts by curettage and packing with plaster-of-Paris pellets [1].
• Antibiotics mixed in plaster of paris have been successful in treating large bony defects in patients with chronic osteomyelitis, and have the advantage of being well tolerated and absorbed by the body [2].
• Allergic contact dermatitis from benzalkonium chloride in plaster of Paris [3].
• Survival of Pseudomonas aeruginosa in plaster of Paris [4].
• He took clinical problems to the laboratory, and made important scientific contributions, particularly in the area of fat embolism and in using calcium sulfate (plaster of Paris) to fill bone defects [5].

High impact information on calcium sulfate

• 1. The discharge of impulses in afferent fibres dissected from the dorsal nerve of the penis of chloralose-anaesthetized rams was recorded electrophysiologically during controlled natural stimulation of the surgically exposed penis maintained at body temperature and mechanically stabilized in a plaster of Paris mould [6].
• Previously, it was found that the FL-SMC lesion increases substantially in size when the intact forelimb is immobilized with a plaster of paris cast for the first 7 days postlesion, which forces extreme overuse of the impaired forelimb during a time when nonlethally damaged tissue is vulnerable to behavioral demand [7].
• A mixture of hydroxyapatite (HA) particles and plaster of Paris (POP) with saline solution was injected into the bone marrow of 30 unilateral tibiae of 30 rabbits [8].
• Stereotactic and functional neurosurgery has experienced a remarkable degree of development during the last 50 years, from the plaster of Paris frame of Spiegel and Wycis to the technology of frameless stereotaxis [9].
• This study investigated the efficacy of a local biodegradable composite composed of hydroxyapatite, plaster of Paris, and chitosan impregnated with antibiotics to treat methicillin-resistant Staphylococcus aureus [10].

Chemical compound and disease context of calcium sulfate

• Gentamicin-loaded plaster of Paris as a treatment of experimental osteomyelitis in rabbits [11].

Biological context of calcium sulfate

• For subjects walking on crutches with the leg encased in a Plaster of Paris cast, the oxygen consumption at these velocities was 12.0, 17.5 and 25.3 ml kg-1 min-1 respectively [12].
• Combined implantation of particulate dentine, plaster of Paris, and a bone xenograft (Bio-Oss) for bone regeneration in rats [13].
• Casting and splinting materials used in orthopedics have historically consisted of plaster of Paris and, more recently, fiberglass [14].
• Effects on bone formation in ovariectomized rats after implantation of tooth ash and plaster of Paris mixture [15].
• When only two rolls of plaster of Paris were used, an average of 80 mL in the 6-month-old and 180 mL in the 3-year-old model were lost, representing 15.7% and 17% of total blood volume, respectively [16].

Anatomical context of calcium sulfate

• Plaster of Paris and Hexelite, a new thermoplastic bandage, were compared in the treatment of 183 patients with malleolar fractures, Colles' fractures or distortions of the finger joints [17].
• The main findings of the study were, first, that impurities in plaster, lead in the plaster or bone matrices, coherent scatter from non-bone tissues and the individual subject's measurement geometry are all minor or negligible effects; and, second, that the synthetic apatite matrix is more representative of bone mineral than is plaster of Paris [18].
• To avoid unequal load-bearing between the two groups, all fractured hindlimbs were immobilized in a plaster of Paris cast [19].
• During the first six postoperative weeks, patients (1) performed active movements of the ankle and subtalar joints but did not bear weight; (2) wore a plaster of paris cast without bearing weight; or (3) bore full weight in a plaster cast [20].
• Effect of dentin preparation and acid etching on the sealing ability of glass ionomer and composite resin when used to repair furcation perforations over plaster of Paris barriers [21].

Associations of calcium sulfate with other chemical compounds

• In this study, F. candida were maintained on a plaster of Paris/graphite substrate for 7 weeks and were supplied with an aqueous suspension of yeast contaminated with Cd, Cu, Pb, and Zn as nitrate salts [22].
• The test materials consisted of two devitalized tissues: boiled bone marrow and demineralized dentin, and six synthetic materials: formalin 10% and 40%, formic acid 10% and 88%, plaster of Paris, and ceramic tricalcium phosphate (Durapatite) [23].
• In vitro elution of gentamicin from Plaster of Paris beads [24].
• METHODS: 15 implantations of calcium sulfate pellets Osteoset (Wright Medical Technology) were performed following resection of bone tumors at our service during 1999 [25].
• In the first 11 children immobilization for treatment was achieved with plaster of Paris casts or aquaplast masks [26].

Gene context of calcium sulfate

• A composite consisting of 1 mg of bone morphogenetic protein (BMP) and 5 mg of plaster of Paris (PLP) was implanted into the mouse femoral muscle [27].
• Sixteen patients with nonunion of femoral shaft fractures were treated by implantation of a composite of bovine bone morphogenetic protein and plaster of Paris (bBMP/PLP) [28].
• Studies concerning the possible osteogenic property of plaster of Paris and its clinical application in human ear surgery are in progress [29].
• An implant of a composite of bovine bone morphogenetic protein and plaster of paris for treatment of femoral shaft nonunions [28].
• Eight weeks after removal of the plaster of Paris she had clinical signs of carpal tunnel syndrome after exercise but without new injuries [30].

Analytical, diagnostic and therapeutic context of calcium sulfate

• With use of this model, we measured the skin surface pressure beneath a plaster-of-Paris cast, a fiberglass cast that had been applied with a standard technique, and a fiberglass cast that had been applied with a stretch-relax technique [31].
• Plaster of paris cast immobilization of the joint was used for three days [32].
• In the treatment group, the tibial defect was filled manually with Osteoset pellets, in the control group the defect was left empty [33].
• There were 3 pintrack infections and 9 patients reported severe discomfort during the postoperative period in a plaster of Paris. After a follow-up of 4 (1-7) years, 28 patients rated the overall result as excellent, while 1 would not have consented to the operation if she had known the result in advance [34].
• Children who had been treated with a tubular bandage and crutches by random selection had a mean time to return of normal activity of 14.22 days compared with 21.60 days for those treated with a plaster-of-Paris cast (t=3.60, p=0.0032; d=7.38, 95% CI 3.0 to 11.8) [35].

References