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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Wounds, Nonpenetrating

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Disease relevance of Wounds, Nonpenetrating

  • Fifty patients with physical findings or mechanisms of injury that were suggestive of possible nonpenetrating injury to the heart were studied with serial creatine phosphokinase isoenzyme (CPK/MB), continuous arrhythmia monitoring, and ECGs for at least 72 hours [1].
  • CONCLUSIONS: Prehospital endotracheal intubation was associated with improved survival in patients with blunt injury and scene Glasgow Coma Score of 8 or less, especially those with severe head injury by anatomic criteria [2].
  • All patients had multiple blunt injuries with cardiac contusion documented electrocardiographically, by CPK isoenzyme determinations, and clinically [3].
  • We report a case of thrombosis of the inferior vena cava after blunt injury managed with interventional radiologic techniques [4].
  • This experimental study was done to determine whether circulating TNF plays a major role in the vasomotor collapse seen following experimental hemorrhage and blunt injury [5].

High impact information on Wounds, Nonpenetrating

  • Gastroesophageal reflux secondary to blunt injury [6].
  • PATIENTS: Trauma patients with blunt injury and scene Glasgow Coma Score of 8 or less, transported by ground ambulance with advanced life support capabilities from January 1, 1991, to December 31, 1995 [2].
  • Systemic heparin sodium anticoagulation and selected extra-anatomic vein graft bypass of the popliteal area are two additional measures that have contributed to a 91% success rate in treatment of popliteal arterial injuries and five of six blunt injuries were treated successfully in this time period [7].
  • Efficacy and tolerability of escin/diethylamine salicylate combination gels in patients with blunt injuries of the extremities [8].
  • In patients with severe blunt injury, hemoglobin, glucose, blood gas, and lactate measurements occasionally result in morbidity-reducing or resource-conserving management changes [9].

Chemical compound and disease context of Wounds, Nonpenetrating

  • We conclude that there is no evidence of oxidant-induced membrane damage manifested by increased plasma levels of CDs or MDA within 2 to 6 hours of blunt injury [10].
  • During eight post-traumatic days, the blood loss and severity of trauma were correlated with the blood levels of lactate, creatinine and catecholamines in 45 patients with multiple blunt injuries [11].
  • In a prospective, controlled study, the effects of large doses of methylprednisolone sodium succinate (MP) were examined in patients subjected to severe blunt injury of the chest [12].
  • This relationship between LP and post-traumatic ischemia is more directly implied from studies showing that pretreatment of cats with high doses of anti-oxidants (e.g., d-alpha tocopherol plus selenium p.o. or 1-ascorbic acid i.v.) can also significantly antagonize the progressive decrease in spinal cord blood flow that follows severe blunt injury [13].

Gene context of Wounds, Nonpenetrating


Analytical, diagnostic and therapeutic context of Wounds, Nonpenetrating


  1. Value of creatine phosphokinase isoenzyme determinations in the diagnosis of myocardial contusion. Lindenbaum, G.A., Carroll, S.F., Block, E.F., Kapusnick, R.A. Annals of emergency medicine. (1988) [Pubmed]
  2. Endotracheal intubation in the field improves survival in patients with severe head injury. Trauma Research and Education Foundation of San Diego. Winchell, R.J., Hoyt, D.B. Archives of surgery (Chicago, Ill. : 1960) (1997) [Pubmed]
  3. Intra-aortic balloon counterpulsation in blunt cardiac injury. Orlando, R., Drezner, A.D. The Journal of trauma. (1983) [Pubmed]
  4. Posttraumatic Budd-Chiari syndrome treated with thrombolytic therapy and angioplasty. Patel, N.H., Bradshaw, B., Meissner, M.H., Townsend, M.F. The Journal of trauma. (1996) [Pubmed]
  5. Experimental hemorrhage and blunt trauma do not increase circulating tumor necrosis factor. Stylianos, S., Wakabayashi, G., Gelfand, J.A., Harris, B.H. The Journal of trauma. (1991) [Pubmed]
  6. Gastroesophageal reflux secondary to blunt injury. Negre, J. Arch. Intern. Med. (1985) [Pubmed]
  7. Improved treatment of popliteal arterial injuries using anticoagulation and extra-anatomic reconstruction. Daugherty, M.E., Sachatello, C.R., Ernst, C.B. Archives of surgery (Chicago, Ill. : 1960) (1978) [Pubmed]
  8. Efficacy and tolerability of escin/diethylamine salicylate combination gels in patients with blunt injuries of the extremities. Pabst, H., Segesser, B., Bulitta, M., Wetzel, D., Bertram, S. International journal of sports medicine. (2001) [Pubmed]
  9. Value of point-of-care blood testing in emergent trauma management. Asimos, A.W., Gibbs, M.A., Marx, J.A., Jacobs, D.G., Erwin, R.J., Norton, H.J., Thomason, M. The Journal of trauma. (2000) [Pubmed]
  10. Early measurement of systemic lipid peroxidation products in the plasma of major blunt trauma patients. Girotti, M.J., Khan, N., McLellan, B.A. The Journal of trauma. (1991) [Pubmed]
  11. Biochemical quantification of blunt injuries. Alho, A., Lahdensuu, M., Jäättelä, A., Avikainen, V., Karaharju, E., Lepistö, P., Rokkanen, P. European journal of intensive care medicine. (1975) [Pubmed]
  12. Corticosteroids in the treatment of blunt injury of the chest. Svennevig, J.L., Bugge-Asperheim, B., Vaage, J., Geiran, O., Birkeland, S. Injury. (1984) [Pubmed]
  13. Role of lipid peroxidation in post-traumatic spinal cord degeneration: a review. Hall, E.D., Braughler, J.M. Central nervous system trauma : journal of the American Paralysis Association. (1986) [Pubmed]
  14. Traumatic myopia; an ultrasonographic and clinical study. Steele, C.A., Tullo, A.B., Marsh, I.B., Storey, J.K. The British journal of ophthalmology. (1987) [Pubmed]
  15. Evolution in the management of the complex liver injury at a Level I trauma center. Cachecho, R., Clas, D., Gersin, K., Grindlinger, G.A. The Journal of trauma. (1998) [Pubmed]
  16. Traumatic ventricular septal defect with tricuspid incompetence. Surgical treatment. Christides, C., Laskar, M., Virot, P., Blanc, P., Doumeix, J.J., Kim, M. The Journal of cardiovascular surgery. (1983) [Pubmed]
  17. Emergency scene endotracheal intubation before and after the introduction of a rapid sequence induction protocol. Falcone, R.E., Herron, H., Dean, B., Werman, H. Air Med. J. (1996) [Pubmed]
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