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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Blood Transfusion

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Disease relevance of Blood Transfusion


Psychiatry related information on Blood Transfusion


High impact information on Blood Transfusion


Chemical compound and disease context of Blood Transfusion


Biological context of Blood Transfusion


Anatomical context of Blood Transfusion


Associations of Blood Transfusion with chemical compounds

  • Antibodies to cephalothin sodium (Keflin) can be transferred passively via whole blood transfusion [31].
  • Widespread adoption of pre-transplant blood transfusion and increasing use of cyclosporin will probably contribute to the further lessening of the centre effect which has already been observed over the past few years [32].
  • 16 patients underwent acute hypervolaemic haemodilution with dextran 40 and Ringers lactate, to see whether this procedure could avoid preoperative blood transfusion [33].
  • Subcutaneous desferrioxamine (2--4 g over 12 h) was administered 6 nights each week to 34 patients with transfusional iron overloads who continued to receive regular blood-transfusions [2].
  • Our investigations suggested that the centre variation in acute rejection was influenced by blood transfusion and the variation in mortality by steroid dose and recipient age [32].

Gene context of Blood Transfusion

  • The question as to whether or not such variables as HLA-A, B, and DR match and sex, the number of pretransplant blood transfusions, and the degree of presensitization, etc. predispose to the development of donor-specific CML nonreactivity was studied as well [34].
  • Individuals possessing the Nak(a)-negative phenotype do not express CD36 and risk developing anti-CD36 isoantibodies upon blood transfusion or during pregnancy [35].
  • In addition, serum markers of immune activation (TNF, sCD23, sCD25) correlated directly with the annual blood transfusion requirement [36].
  • This study was designed to identify HLA-DRB1 alleles associated with predisposition to Jk(a) immunization after blood transfusion or pregnancy [37].
  • CONCLUSION: A DRB1-matched blood transfusion shows improvement of symptoms in several RA patients [38].

Analytical, diagnostic and therapeutic context of Blood Transfusion


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  3. Hyposensitivity to vasopressin in a hemorrhaged-transfused rat model of portal hypertension. Kravetz, D., Cummings, S.A., Groszmann, R.J. Gastroenterology (1987) [Pubmed]
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  7. Sibling adult T-cell leukemia/lymphoma and clustering of human T-cell lymphotropic virus type I infection in a Jamaican family. Wilks, R.J., LaGrenade, L., Hanchard, B., Campbell, M., Murphy, J., Cranston, B., Blattner, W.A., Manns, A. Cancer (1993) [Pubmed]
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  11. Early administration of vapreotide for variceal bleeding in patients with cirrhosis. Calès, P., Masliah, C., Bernard, B., Garnier, P.P., Silvain, C., Szostak-Talbodec, N., Bronowicki, J.P., Ribard, D., Botta-Fridlund, D., Hillon, P., Besseghir, K., Lebrec, D. N. Engl. J. Med. (2001) [Pubmed]
  12. The effect of epoetin beta (recombinant human erythropoietin) on the need for transfusion in very-low-birth-weight infants. European Multicentre Erythropoietin Study Group. Maier, R.F., Obladen, M., Scigalla, P., Linderkamp, O., Duc, G., Hieronimi, G., Halliday, H.L., Versmold, H.T., Moriette, G., Jorch, G. N. Engl. J. Med. (1994) [Pubmed]
  13. HLA-A-matched and HLA-B-matched blood transfusions do not improve kidney allograft survival. Vanrenterghem, Y., Vandeputte, I., Lerut, T., Gruwez, J., Vandeputte, M., Michielsen, P. N. Engl. J. Med. (1983) [Pubmed]
  14. Appearance of beta globin synthesis in erythroid cells of Ferrara beta -o-thalassaemic patients following blood transfusion. Conconi, F., Del Senno, L., Ferrarese, P., Menini, C., Borgatti, L., Vullo, C., Labie, D. Nature (1975) [Pubmed]
  15. Risk factors for acute non-A, non-B hepatitis in the United States and association with hepatitis C virus infection. Alter, M.J., Hadler, S.C., Judson, F.N., Mares, A., Alexander, W.J., Hu, P.Y., Miller, J.K., Moyer, L.A., Fields, H.A., Bradley, D.W. JAMA (1990) [Pubmed]
  16. A phase 3 study of deferasirox (ICL670), a once-daily oral iron chelator, in patients with beta-thalassemia. Cappellini, M.D., Cohen, A., Piga, A., Bejaoui, M., Perrotta, S., Agaoglu, L., Aydinok, Y., Kattamis, A., Kilinc, Y., Porter, J., Capra, M., Galanello, R., Fattoum, S., Drelichman, G., Magnano, C., Verissimo, M., Athanassiou-Metaxa, M., Giardina, P., Kourakli-Symeonidis, A., Janka-Schaub, G., Coates, T., Vermylen, C., Olivieri, N., Thuret, I., Opitz, H., Ressayre-Djaffer, C., Marks, P., Alberti, D. Blood (2006) [Pubmed]
  17. Which patients with hepatitis C develop liver complications? Khan, M.H., Farrell, G.C., Byth, K., Lin, R., Weltman, M., George, J., Samarasinghe, D., Kench, J., Kaba, S., Crewe, E., Liddle, C. Hepatology (2000) [Pubmed]
  18. Haematopoietic growth factors as supportive therapy in HIV-infected patients. Hermans, P. AIDS (1995) [Pubmed]
  19. Association of sepsis with an immunosuppressive polypeptide in the serum of burn patients. Constantian, M.B. Ann. Surg. (1978) [Pubmed]
  20. Thalidomide for treatment of severe intestinal bleeding. Bauditz, J., Schachschal, G., Wedel, S., Lochs, H. Gut (2004) [Pubmed]
  21. Possible mechanism of action of transfusion effect in renal transplantation. MacLeod, A.M., Power, D.A., Mason, R.J., Stewart, K.N., Shewan, W.G., Edward, N., Catto, G.R. Lancet (1982) [Pubmed]
  22. Pharmacological strategies to decrease excessive blood loss in cardiac surgery: a meta-analysis of clinically relevant endpoints. Levi, M., Cromheecke, M.E., de Jonge, E., Prins, M.H., de Mol, B.J., Briët, E., Büller, H.R. Lancet (1999) [Pubmed]
  23. Clinical outcome of hepatitis C as a function of mode of transmission. Gordon, S.C., Bayati, N., Silverman, A.L. Hepatology (1998) [Pubmed]
  24. Allogeneic marrow transplantation after total lymphoid irradiation (TLI): effect of dose/fraction, thymic irradiation, delayed marrow infusion, and presensitization. Gottlieb, M., Strober, S., Kaplan, H.S. J. Immunol. (1979) [Pubmed]
  25. Perioperative erythropoietin administration in patients with gastrointestinal tract cancer: prospective randomized double-blind study. Kosmadakis, N., Messaris, E., Maris, A., Katsaragakis, S., Leandros, E., Konstadoulakis, M.M., Androulakis, G. Ann. Surg. (2003) [Pubmed]
  26. Induction of antiidiotypic antibodies by blood transfusions. Characterization of T cell alloantigen-specific receptors by sera from transfused mice. Singal, D.P., Ludwin, D., Joseph, S., Blajchman, M.A., Ofosu, F.A., Liao, S.K. Transplantation (1986) [Pubmed]
  27. Moderate effect of preoperative blood transfusions on pancreas allograft survival in rats and dogs. Spillenaar-Bilgen, E.J., de Bruin, R.W., Baumgartner, D., Jeekel, J., Marquet, R.L. Transplantation (1990) [Pubmed]
  28. Alloreactive T suppressor cells in the rat. I. Evidence of three distinct subsets of splenic suppressor T cells resistant to cyclosporine. Rodrigues, M.A., Hutchinson, I.V., Morris, P.J. Transplantation (1989) [Pubmed]
  29. An increase of donor-specific T helper precursors resulting from blood transfusions. Vandekerckhove, B.A., Datema, G., Zantvoort, F., Claas, F.H. Transplantation (1990) [Pubmed]
  30. Effects of blood transfusion on oxygen transport variables in severe sepsis. Lorente, J.A., Landín, L., De Pablo, R., Renes, E., Rodríguez-Díaz, R., Liste, D. Crit. Care Med. (1993) [Pubmed]
  31. Allergic reaction to transfused cephalothin antibody. Branch, D.R., Gifford, H. JAMA (1979) [Pubmed]
  32. Renal transplantation in the United Kingdom and Ireland--the centre effect. Taylor, R.M., Ting, A., Briggs, J.D. Lancet (1985) [Pubmed]
  33. Acute hypervolaemic haemodilution to avoid blood transfusion during major surgery. Trouwborst, A., van Woerkens, E.C., van Daele, M., Tenbrinck, R. Lancet (1990) [Pubmed]
  34. Cell-mediated lympholysis studies in renal allograft recipients. Goulmy, E., Persijn, G., Blokland, E., D'Amaro, J., van Rood, J.J. Transplantation (1981) [Pubmed]
  35. A structural/functional domain on human CD36 is involved in the binding of anti-Nak(a) antibodies. Daviet, L., Morel-Kopp, M.C., Kaplan, C., McGregor, J.L. Thromb. Haemost. (1995) [Pubmed]
  36. Serum levels of cytokines and soluble antigens in polytransfused patients with beta-thalassemia major: relationship to immune status. Lombardi, G., Matera, R., Minervini, M.M., Cascavilla, N., D'Arcangelo, P., Carotenuto, M., Di Giorgio, G., Musto, P. Haematologica (1994) [Pubmed]
  37. HLA-DRB1 alleles and Jk(a) immunization. Reviron, D., Dettori, I., Ferrera, V., Legrand, D., Touinssi, M., Mercier, P., de Micco, P., Chiaroni, J. Transfusion (2005) [Pubmed]
  38. The influence of a partially HLA-matched blood transfusion on the disease activity of rheumatoid arthritis. van der Horst-Bruinsma, I.E., Huizinga, T.W., Lagaay, E.M., Hazes, J.M., Breedveld, F.C., Schreuder, G.M., Tomson, T.A., Zwinderman, A.H., van Rood, J.J., de Vries, R.R. Rheumatology (Oxford, England) (1999) [Pubmed]
  39. Cyclosporin and blood transfusion in kidney transplantation. Niessen, G.J., Marquet, R.L., Obertop, H., Bijnen, A.B., Jeekel, J. Lancet (1984) [Pubmed]
  40. Emergency sclerotherapy versus vasoactive drugs for variceal bleeding in cirrhosis: a Cochrane meta-analysis. D'Amico, G., Pietrosi, G., Tarantino, I., Pagliaro, L. Gastroenterology (2003) [Pubmed]
  41. Misoprostol and illegal abortion in Rio de Janeiro, Brazil. Costa, S.H., Vessey, M.P. Lancet (1993) [Pubmed]
  42. Spontaneous retroperitoneal bleeding in patients on chronic hemodialysis. Milutinovich, J., Follette, W.C., Scribner, B.H. Ann. Intern. Med. (1977) [Pubmed]
  43. OncoSurge: a strategy for improving resectability with curative intent in metastatic colorectal cancer. Poston, G.J., Adam, R., Alberts, S., Curley, S., Figueras, J., Haller, D., Kunstlinger, F., Mentha, G., Nordlinger, B., Patt, Y., Primrose, J., Roh, M., Rougier, P., Ruers, T., Schmoll, H.J., Valls, C., Vauthey, N.J., Cornelis, M., Kahan, J.P. J. Clin. Oncol. (2005) [Pubmed]
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