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MeSH Review

Carpal Bones

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Disease relevance of Carpal Bones


High impact information on Carpal Bones

  • We found that Hoxd-11-/- mutant mice are viable and display homeotic transformations of their sacral vertebrae, while their forelimbs present abnormalities of some metacarpals and of the first row of carpal bones [6].
  • In addition, 9 patients had cystic radiolucencies of bone, which were interpreted as having resulted from local amyloid deposits, involving carpal bones, humeral heads, femoral heads, acetabula, or tibial plateaus [7].
  • Targeted mutation of the Hoxd11 gene causes reduced male fertility, vertebral transformation, carpal bone fusions, and reductions in digit length [8].
  • Important radiological signs included calcification of the falx cerebri in 65%, of the tentorium cerebelli in 20%, bridged sella in 68%, bifid ribs in 26%, hemivertebrae in 15%, fusion of the vertebral bodies in 10%, and flame shaped lucencies of the phalanges, metacarpal, and carpal bones of the hands in 30% [9].
  • An iliac graft is sandwiched in a coronal split in the radius and carpal bones [10].

Chemical compound and disease context of Carpal Bones


Anatomical context of Carpal Bones


Associations of Carpal Bones with chemical compounds

  • MR reliably imaged the flexor retinaculum and carpal bones and thus defined the borders of the carpal tunnel [13].
  • Changes in contact area and pressure distribution with loading were evaluated on the proximal articulating surface of the equine third carpal bone using safranin-O dye staining and pressure sensitive film techniques [14].
  • The medial PICL had a large origin distally on the lateral aspect of the radial carpal bone (Cr) and attached to third (C3) and second (C2) carpal bones with apparently separate fibre orientations [15].
  • METHODS: Each of 3 clinicians injected 0.5 mL of a 1% aqueous solution of new methylene blue as a marker at the medial aspect of the accessory carpal bone of 10 limbs [16].
  • Image analysis was used to assess photodensity (compared to a known thickness of aluminium) of four regions of interest (ROI) in C3 and one ROI in the fourth carpal bone (C4) of 14 isolated distal rows of carpal bones of the horse [17].

Gene context of Carpal Bones


  1. Carpal tunnel syndrome with cystic bone lesions secondary to amyloidosis in chronic hemodialysis patients. Fenves, A.Z., Emmett, M., White, M.G., Greenway, G., Michaels, D.B. Am. J. Kidney Dis. (1986) [Pubmed]
  2. Turner syndrome and osteoporosis: mechanisms and prognosis. Rubin, K. Pediatrics (1998) [Pubmed]
  3. Amyloid and non-amyloid carpal tunnel syndrome in patients receiving chronic renal dialysis. Chary-Valckenaere, I., Kessler, M., Mainard, D., Schertz, L., Chanliau, J., Champigneulle, J., Pourel, J., Gaucher, A., Netter, P. J. Rheumatol. (1998) [Pubmed]
  4. Desbuquois syndrome presenting with severe neonatal dwarfism, spondylo-epiphyseal dysplasia and advanced carpal bone age. Jéquier, S., Perreault, G., Maroteaux, P. Pediatric radiology. (1992) [Pubmed]
  5. Coexistence of ochronosis and rheumatoid arthritis. Kihara, T., Yasuda, M., Watanabe, H., Suenaga, Y., Shiokawa, S., Wada, T., Nonaka, S., Suzuki, T., Nobunaga, M. Clin. Rheumatol. (1994) [Pubmed]
  6. Axial skeleton homeosis and forelimb malformations in Hoxd-11 mutant mice. Favier, B., Le Meur, M., Chambon, P., Dollé, P. Proc. Natl. Acad. Sci. U.S.A. (1995) [Pubmed]
  7. Synovial amyloidosis in patients undergoing long-term hemodialysis. Bardin, T., Kuntz, D., Zingraff, J., Voisin, M.C., Zelmar, A., Lansaman, J. Arthritis Rheum. (1985) [Pubmed]
  8. Duplication of the Hoxd11 gene causes alterations in the axial and appendicular skeleton of the mouse. Boulet, A.M., Capecchi, M.R. Dev. Biol. (2002) [Pubmed]
  9. Clinical manifestations in 105 persons with nevoid basal cell carcinoma syndrome. Kimonis, V.E., Goldstein, A.M., Pastakia, B., Yang, M.L., Kase, R., DiGiovanna, J.J., Bale, A.E., Bale, S.J. Am. J. Med. Genet. (1997) [Pubmed]
  10. Wrist arthrodesis in paralyzed arms of children. Makin, M. The Journal of bone and joint surgery. American volume. (1977) [Pubmed]
  11. Immunohistochemical analysis of an equine model of synovitis-induced arthritis. Todhunter, P.G., Kincaid, S.A., Todhunter, R.J., Kammermann, J.R., Johnstone, B., Baird, A.N., Hanson, R.R., Wright, J.M., Lin, H.C., Purohit, R.C. Am. J. Vet. Res. (1996) [Pubmed]
  12. Inflammation as the possible cause of cystic radiolucencies in carpal bones of patients on hemodialysis. Ogawa, H., Saito, A., Ono, M. ASAIO transactions / American Society for Artificial Internal Organs. (1989) [Pubmed]
  13. MR imaging of the carpal tunnel: normal anatomy and preliminary findings in the carpal tunnel syndrome. Middleton, W.D., Kneeland, J.B., Kellman, G.M., Cates, J.D., Sanger, J.R., Jesmanowicz, A., Froncisz, W., Hyde, J.S. AJR. American journal of roentgenology. (1987) [Pubmed]
  14. Contact area and pressure distribution changes of the equine third carpal bone during loading. Palmer, J.L., Bertone, A.L., Litsky, A.S. Equine Vet. J. (1994) [Pubmed]
  15. Observations on the anatomy and pathology of the palmar intercarpal ligaments in the middle carpal joints of thoroughbred racehorses. Phillips, T.J., Wright, I.M. Equine Vet. J. (1994) [Pubmed]
  16. A new approach for perineural injection of the lateral palmar nerve in the horse. Castro, F.A., Schumacher, J.S., Pauwels, F., Blackford, J.T. Veterinary surgery : VS : the official journal of the American College of Veterinary Surgeons. (2005) [Pubmed]
  17. The quantitative assessment of photodensity of the third carpal bone in the horse. Secombe, C.J., Firth, E.C., Perkins, N.R., Bailey, D., Anderson, B.H. New Zealand veterinary journal. (2004) [Pubmed]
  18. Carpal canal stenosis in men with idiopathic carpal tunnel syndrome. Papaioannou, T., Rushworth, G., Atar, D., Dekel, S. Clin. Orthop. Relat. Res. (1992) [Pubmed]
  19. MRI of the abnormal pediatric hand and wrist with plain film correlation. Azouz, E.M., Babyn, P.S., Mascia, A.T., Tuuha, S.E., Décarie, J.C. Journal of computer assisted tomography. (1998) [Pubmed]
  20. Experimental investigation of the scaphoid strain during wrist motion. Romdhane, L., Chidgey, L., Miller, G., Dell, P. Journal of biomechanics. (1990) [Pubmed]
  21. Spontaneous flexor tendon rupture in the palm. Wray, R.C., Parlin, L.S. Annals of plastic surgery. (1989) [Pubmed]
  22. Correlation of wrist ligamentotaxis with carpal distraction: implications for external fixation. Loebig, T.G., Badia, A., Anderson, D.D., Baratz, M.E. The Journal of hand surgery. (1997) [Pubmed]
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