Chemical Compound Review:
FK-888 (2S,4R)-N-[(1S)-1-(benzyl- methyl...
Synonyms:
SureCN8079679, FK888, LS-193299, FK 888, PDSP2_000648, ...
- Inhibition of emesis by tachykinin NK1 receptor antagonists in Suncus murinus (house musk shrew). Rudd, J.A., Ngan, M.P., Wai, M.K. Eur. J. Pharmacol. (1999)
- A neurokinin 1-receptor antagonist improves exercise-induced airway narrowing in asthmatic patients. Ichinose, M., Miura, M., Yamauchi, H., Kageyama, N., Tomaki, M., Oyake, T., Ohuchi, Y., Hida, W., Miki, H., Tamura, G., Shirato, K. Am. J. Respir. Crit. Care Med. (1996)
- Role of substance P in cough during bronchoconstriction in awake guinea pigs. Sekizawa, K., Ebihara, T., Sasaki, H. Am. J. Respir. Crit. Care Med. (1995)
- Evidence for a common molecular mode of action for chemically distinct nonpeptide antagonists at the neurokinin-1 (substance P) receptor. Gether, U., Emonds-Alt, X., Brelière, J.C., Fujii, T., Hagiwara, D., Pradier, L., Garret, C., Johansen, T.E., Schwartz, T.W. Mol. Pharmacol. (1994)
- The species selectivity of chemically distinct tachykinin nonpeptide antagonists is dependent on common divergent residues of the rat and human neurokinin-1 receptors. Jensen, C.J., Gerard, N.P., Schwartz, T.W., Gether, U. Mol. Pharmacol. (1994)
- Investigation of the specificity of FK 888 as a tachykinin NK1 receptor antagonist. Wang, Z.Y., Tung, S.R., Strichartz, G.R., Håkanson, R. Br. J. Pharmacol. (1994)
- Comparative, general pharmacology of SDZ NKT 343, a novel, selective NK1 receptor antagonist. Walpole, C.S., Brown, M.C., James, I.F., Campbell, E.A., McIntyre, P., Docherty, R., Ko, S., Hedley, L., Ewan, S., Buchheit, K.H., Urban, L.A. Br. J. Pharmacol. (1998)
- Role of substance P in experimental allergic conjunctivitis in guinea pigs. Yamaji, M., Takada, M., Fujiwara, R., Ohishi, H., Izushi, K., Sugimoto, Y., Kamei, C. Methods and findings in experimental and clinical pharmacology. (1997)
- Esophageal stimulation by hydrochloric acid causes neurogenic inflammation in the airways in guinea pigs. Hamamoto, J., Kohrogi, H., Kawano, O., Iwagoe, H., Fujii, K., Hirata, N., Ando, M. J. Appl. Physiol. (1997)
- A substance P receptor antagonist (FK 888) modifies gut alterations induced by ionizing radiation. Esposito, V., Linard, C., Wysocki, J., Griffiths, N.M., Mathe, D. Int. J. Radiat. Biol. (1998)
- The role of neuropeptides and capsaicin-sensitive fibres in glutamate-induced nociception and paw oedema in mice. Beirith, A., Santos, A.R., Calixto, J.B. Brain Res. (2003)
- The tachykinin NK1 receptor mediates the migration-promoting effect of substance P on human skin fibroblasts in culture. Parenti, A., Amerini, S., Ledda, F., Maggi, C.A., Ziche, M. Naunyn Schmiedebergs Arch. Pharmacol. (1996)
- Analysis of the mechanisms underlying the contractile response induced by the hydroalcoholic extract of Phyllanthus urinaria in the guinea-pig urinary bladder in-vitro. Dias, M.A., Campos, A.H., Cechinel Filho, V., Yunes, R.A., Calixto, J.B. J. Pharm. Pharmacol. (1995)
- Further evidence for the involvement of tachykinin receptor subtypes in formalin and capsaicin models of pain in mice. Santos, A.R., Calixto, J.B. Neuropeptides (1997)
- Effect of the non-peptide blocker (+/-) CP 96,345 on the cellular mechanism involved in the response to NK1 receptor stimulation in human skin fibroblasts. Ziche, M., Parenti, A., Amerini, S., Zawieja, D., Maggi, C.A., Ledda, F. Neuropeptides (1996)
- Effect of the tachykinin receptor antagonists, SR 140333, FK 888, and SR 142801, on capsaicin-induced mouse ear oedema. Inoue, H., Nagata, N., Koshihara, Y. Inflamm. Res. (1996)
- Evidence that tachykinin NK2 receptors modulate resting tone in the rat isolated small intestine. Maggi, C.A., Giuliani, S. Br. J. Pharmacol. (1996)