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Chemical Compound Review

AC1L3GUT     2,4,6,8,10,12-hexaoxido- 1,3,5,7,9,11...

Synonyms: CTK8D8998, AR-1I3055, AC1Q22JV, 13478-98-3, Hexametaphosphate, ...
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Disease relevance of Hexametaphosphate


High impact information on Hexametaphosphate


Chemical compound and disease context of Hexametaphosphate


Biological context of Hexametaphosphate


Anatomical context of Hexametaphosphate


Associations of Hexametaphosphate with other chemical compounds


Gene context of Hexametaphosphate

  • Pre-treatment with a sodium hexametaphosphate dentifrice (Crest Dual Action Whitening) reduced tea adsorption to powdered apatite, while post-treatments of pre-stained powder resulted in desorption of tea components [16].

Analytical, diagnostic and therapeutic context of Hexametaphosphate

  • Alternatively, analytical ultracentrifugation reveals protein association from the increase in apparent sedimentation coefficients of cytochrome c in the presence of equimolar hexametaphosphate [17].
  • OBJECTIVE: This study was a randomized, controlled, examiner-blind, four-period crossover design that examined the prevention of induced stain deposition through the use of chewing gums containing either 2.0% or 3.0% sodium hexametaphosphate (Na Hex) [18].
  • At three and six weeks, adjusted stain scores were highest in the control group and generally lowest in the sodium hexametaphosphate group for all Lobene parameters (intensity, area and composite) [19].


  1. Sodium hexametaphosphate sensitizes Pseudomonas aeruginosa, several other species of Pseudomonas, and Escherichia coli to hydrophobic drugs. Vaara, M., Jaakkola, J. Antimicrob. Agents Chemother. (1989) [Pubmed]
  2. Combined effect of hop resins and sodium hexametaphosphate against certain strains of Escherichia coli. Fukao, T., Sawada, H., Ohta, Y. J. Food Prot. (2000) [Pubmed]
  3. Effect of sodium hexametaphosphate on dental calculus formation in dogs. Stookey, G.K., Warrick, J.M., Miller, L.L. Am. J. Vet. Res. (1995) [Pubmed]
  4. The comparative efficacy of stabilized stannous fluoride/sodium hexametaphosphate dentifrice and sodium fluoride/triclosan/copolymer dentifrice for the control of gingivitis: a 6-month randomized clinical study. Archila, L., Bartizek, R.D., Winston, J.L., Biesbrock, A.R., McClanahan, S.F., He, T. J. Periodontol. (2004) [Pubmed]
  5. Efficacy and safety of a novel stabilized stannous fluoride and sodium hexametaphosphate dentifrice for dentinal hypersensitivity. Schiff, T., He, T., Sagel, L., Baker, R. The journal of contemporary dental practice [electronic resource]. (2006) [Pubmed]
  6. Modification of technological properties of fish protein concentrates. Sikorski, Z.E., Naczk, M. Critical reviews in food science and nutrition. (1981) [Pubmed]
  7. Influence of dentifrices and dietary components in saliva on wettability of pellicle-coated enamel in vitro and in vivo. van der Mei, H.C., White, D.J., Kamminga-Rasker, H.J., Knight, J., Baig, A.A., Smit, J., Busscher, H.J. Eur. J. Oral Sci. (2002) [Pubmed]
  8. Effect of preparation conditions on properties and permeability of chitosan-sodium hexametaphosphate capsules. Angelova, N., Hunkeler, D. Journal of biomaterials science. Polymer edition. (2001) [Pubmed]
  9. Fluorometric assessment of gram-negative bacterial permeabilization. Helander, I.M., Mattila-Sandholm, T. J. Appl. Microbiol. (2000) [Pubmed]
  10. A 24-hour dental plaque prevention study with a stannous fluoride dentifrice containing hexametaphosphate. White, D.J., Kozak, K.M., Gibb, R., Dunavent, J., Klukowska, M., Sagel, P.A. The journal of contemporary dental practice [electronic resource]. (2006) [Pubmed]
  11. Phosphate glass as a phosphate source in high cell density Escherichia coli fermentations. Curless, C., Baclaski, J., Sachdev, R. Biotechnol. Prog. (1996) [Pubmed]
  12. Hexametaphosphate effects on tooth surface conditioning film chemistry--in vitro and in vivo studies. Busscher, H.J., White, D.J., van der Mei, H.C., Baig, A.A., Kozak, K.M. The Journal of clinical dentistry. (2002) [Pubmed]
  13. Time-dependent marinade absorption and retention, cooking yield, and palatability of chicken filets marinated in various phosphate solutions. Xiong, Y.L., Kupski, D.R. Poult. Sci. (1999) [Pubmed]
  14. Anticaries potential of a stabilized stannous fluoride/sodium hexametaphosphate dentifrice. Pfarrer, A.M., McQueen, C.M., Lawless, M.A., Rapozo-Hilo, M., Featherstone, J.D. Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995) (2005) [Pubmed]
  15. Extrinsic whitening effects of sodium hexametaphosphate--a review including a dentifrice with stabilized stannous fluoride. Baig, A., He, T., Buisson, J., Sagel, L., Suszcynsky-Meister, E., White, D.J. Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995) (2005) [Pubmed]
  16. Laboratory studies on the chemical whitening effects of a sodium hexametaphosphate dentifrice. Baig, A.A., Kozak, K.M., Cox, E.R., Zoladz, J.R., Mahony, L., White, D.J. The Journal of clinical dentistry. (2002) [Pubmed]
  17. The promotion of self-association of horse-heart cytochrome c by hexametaphosphate anions. Whitford, D., Concar, D.W., Williams, R.J. Eur. J. Biochem. (1991) [Pubmed]
  18. The prevention of induced stain using two levels of sodium hexametaphosphate in chewing gum. Bartizek, R.D., Walters, P., Biesbrock, A.R. The Journal of clinical dentistry. (2003) [Pubmed]
  19. Extrinsic stain prevention with a combination dentifrice containing calcium phosphate surface active builders compared to two marketed controls. Gerlach, R.W., Ramsey, L.L., Baker, R.A., White, D.J. The Journal of clinical dentistry. (2002) [Pubmed]
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