Disease relevance of Hexametaphosphate

• Sodium hexametaphosphate sensitizes Pseudomonas aeruginosa, several other species of Pseudomonas, and Escherichia coli to hydrophobic drugs [1].
• Combined effect of hop resins and sodium hexametaphosphate against certain strains of Escherichia coli [2].
• Effect of sodium hexametaphosphate on dental calculus formation in dogs [3].
• The comparative efficacy of stabilized stannous fluoride/sodium hexametaphosphate dentifrice and sodium fluoride/triclosan/copolymer dentifrice for the control of gingivitis: a 6-month randomized clinical study [4].
• Efficacy and safety of a novel stabilized stannous fluoride and sodium hexametaphosphate dentifrice for dentinal hypersensitivity [5].

High impact information on Hexametaphosphate

• The best results have been obtained by partial hydrolysis of acylated proteins or precipitation of the aggregated products using sodium hexametaphosphate [6].
• Exposure of pellicles formed from saliva with milk added to various dentifrices had a variable effect on bacterial adhesion: markedly lower numbers of adhering S. oralis were found for a dentifrice with NaF, but exposure to dentifrices containing SnF2 or hexametaphosphate showed slightly increased adhesion [7].
• Effect of preparation conditions on properties and permeability of chitosan-sodium hexametaphosphate capsules [8].
• With Escherichia coli O157, Pseudomonas aeruginosa, and Salmonella typhimurium as test organisms and ethylenediaminetetraacetic acid and sodium hexametaphosphate as the model permeabilizers, quantitative and highly reproducible NPN uptake levels were obtained that differed characteristically between the test bacteria [9].
• The combined antimicrobial effects of hop resins with sodium hexametaphosphate, glycerol monocaprate, and lysozyme were investigated aiming to make an effective agent against Escherichia coli [2].

Chemical compound and disease context of Hexametaphosphate

• A 24-hour dental plaque prevention study with a stannous fluoride dentifrice containing hexametaphosphate [10].

Biological context of Hexametaphosphate

• Polyphosphate glass (sodium hexametaphosphate, sodium polyphosphate, glassy) was identified and tested as a source of phosphate that supports growth of recombinant Escherichia coli to cell densities over 110 g dry wt/L [11].

Anatomical context of Hexametaphosphate

• These studies compared the effects of Crest Dual Action Whitening dentifrice with sodium hexametaphosphate and control commercial dentifrices on the surface chemistry of conditioning film-coated dental enamel in vitro and in vivo [12].

Associations of Hexametaphosphate with other chemical compounds

• The rate of marinade absorption increased markedly (P < 0.05) by the presence of either high (3.2%) or low (1.6%) concentrations of sodium phosphates in the order: pyrophosphate (PP) > tripolyphosphate (TPP) > hexametaphosphate (HMP) [13].
• This series of well-controlled and validated in vitro studies demonstrates the anticaries potential of the stabilized stannous fluoride/sodium hexametaphosphate dentifrice [14].
• Sodium hexametaphosphate was originally introduced in a sodium fluoride dentifrice formulation and was later marketed in a chewing gum delivery system [15].

Gene context of Hexametaphosphate

• Pre-treatment with a sodium hexametaphosphate dentifrice (Crest Dual Action Whitening) reduced tea adsorption to powdered apatite, while post-treatments of pre-stained powder resulted in desorption of tea components [16].

Analytical, diagnostic and therapeutic context of Hexametaphosphate

• Alternatively, analytical ultracentrifugation reveals protein association from the increase in apparent sedimentation coefficients of cytochrome c in the presence of equimolar hexametaphosphate [17].
• OBJECTIVE: This study was a randomized, controlled, examiner-blind, four-period crossover design that examined the prevention of induced stain deposition through the use of chewing gums containing either 2.0% or 3.0% sodium hexametaphosphate (Na Hex) [18].
• At three and six weeks, adjusted stain scores were highest in the control group and generally lowest in the sodium hexametaphosphate group for all Lobene parameters (intensity, area and composite) [19].

References