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MeSH Review

Dental Enamel

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Disease relevance of Dental Enamel


High impact information on Dental Enamel

  • Dental-enamel hypoplasia and keratopathy were also frequent but were not attributable to hypoparathyroidism [3].
  • Amelogenins, a family of extracellular matrix proteins of the dental enamel, are transiently but abundantly expressed by ameloblasts during tooth development [4].
  • Phosphorus-31 solid state nuclear magnetic resonance (NMR) spin-spin relaxation studies were carried out on bovine bone and dental enamel crystals of different ages and the data were compared with those obtained from pure and carbonated hydroxyapatites [5].
  • Our results confirm that significantly increased numbers of dental enamel pits are found in persons with TS compared to controls [6].
  • Since type V collagen is not present in dental enamel but is an otherwise widely distributed collagen, and since only active MMP-20 has been observed in teeth, our data suggest that control of MMP-20 activity is primarily regulated by transcriptional means [7].

Biological context of Dental Enamel


Anatomical context of Dental Enamel


Associations of Dental Enamel with chemical compounds

  • Thus, a series of additional experiments will be necessary for more insight into the reaction mechanisms of fluoride on superficial dental enamel [17].
  • All of the findings were consistent with the hypothesis that CO2 laser irradiation converts dental enamel to hydroxyapatite (HAP) possessing site #2 character (Yamamoto et al., 1986) [18].
  • CO2 laser inhibitor of artificial caries-like lesion progression in dental enamel [19].
  • Incorporation of tetracyline into dental enamels was studied by exposing presoftened enamel slabs to tetracycline-containing mineralizing solutions [20].
  • It is suggested that a reduced calcium fluoride dissolution rate, in the presence of phosphate, can account for the relatively slow loss of calcium fluoride from dental enamel observed in recent clinical studies [21].

Gene context of Dental Enamel


Analytical, diagnostic and therapeutic context of Dental Enamel


  1. Fluoride effect on the activity of enamel matrix proteinases in vitro. Gerlach, R.F., de Souza, A.P., Cury, J.A., Line, S.R. Eur. J. Oral Sci. (2000) [Pubmed]
  2. Microanatomy of the dental enamel in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED): report of three cases. Lukinmaa, P.L., Waltimo, J., Pirinen, S. J. Craniofac. Genet. Dev. Biol. (1996) [Pubmed]
  3. Clinical variation of autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) in a series of 68 patients. Ahonen, P., Myllärniemi, S., Sipilä, I., Perheentupa, J. N. Engl. J. Med. (1990) [Pubmed]
  4. The human enamel protein gene amelogenin is expressed from both the X and the Y chromosomes. Salido, E.C., Yen, P.H., Koprivnikar, K., Yu, L.C., Shapiro, L.J. Am. J. Hum. Genet. (1992) [Pubmed]
  5. Nuclear magnetic resonance spin-spin relaxation of the crystals of bone, dental enamel, and synthetic hydroxyapatites. Wu, Y., Ackerman, J.L., Kim, H.M., Rey, C., Barroug, A., Glimcher, M.J. J. Bone Miner. Res. (2002) [Pubmed]
  6. Developmental enamel defects in tuberous sclerosis: a clinical genetic marker? Flanagan, N., O'Connor, W.J., McCartan, B., Miller, S., McMenamin, J., Watson, R. J. Med. Genet. (1997) [Pubmed]
  7. MMP-20 is predominately a tooth-specific enzyme with a deep catalytic pocket that hydrolyzes type V collagen. Turk, B.E., Lee, D.H., Yamakoshi, Y., Klingenhoff, A., Reichenberger, E., Wright, J.T., Simmer, J.P., Komisarof, J.A., Cantley, L.C., Bartlett, J.D. Biochemistry (2006) [Pubmed]
  8. Kinetics and mechanism of hydroxyapatite crystal dissolution in weak acid buffers using the rotating disk method. Wu, M.S., Higuchi, W.I., Fox, J.L., Friedman, M. J. Dent. Res. (1976) [Pubmed]
  9. A study of the effect of fluoride delivered from solution and dentifrices on enamel demineralization. Page, D.J. Caries Res. (1991) [Pubmed]
  10. Study on the effect of fluoride ion concentration in different water supplies on the incorporation of the fluoride ion in dental enamel. Abdel Fattah, L.E., Mohamed, Z.H., Soliman, N., Galal, A. Egyptian dental journal. (1985) [Pubmed]
  11. Distribution and structure of dental enamel in incisors of Tabby mice. Risnes, S., Peterkova, R., Lesot, H. Arch. Oral Biol. (2005) [Pubmed]
  12. Detection of mature collagen in human dental enamel. Açil, Y., Mobasseri, A.E., Warnke, P.H., Terheyden, H., Wiltfang, J., Springer, I. Calcif. Tissue Int. (2005) [Pubmed]
  13. Salivary clearance of citric acid after an oral rinse. Bashir, E., Ekberg, O., Lagerlöf, F. Journal of dentistry. (1995) [Pubmed]
  14. Immunohistochemical localization of transcription factor Sp3 during dental enamel development in rat tooth germ. Lv, P., Jia, H.T., Gao, X.J. Eur. J. Oral Sci. (2006) [Pubmed]
  15. Fluorine microanalysis in teeth. Torrisi, L., Foti, G., Campisano, S.U. Clinical materials. (1990) [Pubmed]
  16. Amelogenin proteins of developing dental enamel. Fincham, A.G., Simmer, J.P. Ciba Found. Symp. (1997) [Pubmed]
  17. Electron spectroscopic studies of interactions between superficially-applied fluorides and surface enamel. Uchtmann, H., Duschner, H. J. Dent. Res. (1982) [Pubmed]
  18. Initial dissolution rate studies on dental enamel after CO2 laser irradiation. Fox, J.L., Yu, D., Otsuka, M., Higuchi, W.I., Wong, J., Powell, G.L. J. Dent. Res. (1992) [Pubmed]
  19. CO2 laser inhibitor of artificial caries-like lesion progression in dental enamel. Featherstone, J.D., Barrett-Vespone, N.A., Fried, D., Kantorowitz, Z., Seka, W. J. Dent. Res. (1998) [Pubmed]
  20. In vitro studies of the phenomenon of tetracycline incorporation into enamel. Lambrou, D.B., Tahos, B.S., Lambrou, K.D. J. Dent. Res. (1977) [Pubmed]
  21. Effects of inorganic orthophosphate and pyrophosphate on dissolution of calcium fluoride in water. Lagerlöf, F., Saxegaard, E., Barkvoll, P., Rølla, G. J. Dent. Res. (1988) [Pubmed]
  22. Expression, structure, and function of enamel proteinases. Simmer, J.P., Hu, J.C. Connect. Tissue Res. (2002) [Pubmed]
  23. Enamelin and autosomal-dominant amelogenesis imperfecta. Hu, J.C., Yamakoshi, Y. Crit. Rev. Oral Biol. Med. (2003) [Pubmed]
  24. Cloning and characterization of the mouse and human enamelin genes. Hu, J.C., Zhang, C.H., Yang, Y., Kärrman-Mårdh, C., Forsman-Semb, K., Simmer, J.P. J. Dent. Res. (2001) [Pubmed]
  25. Human developing enamel proteins exhibit a sex-linked dimorphism. Fincham, A.G., Bessem, C.C., Lau, E.C., Pavlova, Z., Shuler, C., Slavkin, H.C., Snead, M.L. Calcif. Tissue Int. (1991) [Pubmed]
  26. Dental enamel defects in celiac disease. Aine, L., Mäki, M., Collin, P., Keyriläinen, O. J. Oral Pathol. Med. (1990) [Pubmed]
  27. Quantitative microradiography for studying dental enamel demineralization and remineralization. Bergstrom, D.H., Fox, J.L., Higuchi, W.I. Journal of pharmaceutical sciences. (1984) [Pubmed]
  28. Scanning electron microscopy study of dental enamel surface exposed to 35% hydrogen peroxide: alone, with saliva, and with 10% carbamide peroxide. Spalding, M., Taveira, L.A., de Assis, G.F. Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] (2003) [Pubmed]
  29. Proton activation analysis studies on fluorine and nitrogen content of developing dental enamel. Ahlberg, M., Bawden, J.W., Hammarström, L.E., Hellborg, R. Odontologisk revy. (1975) [Pubmed]
  30. The effect of restorative materials on the wear of human enamel. Ratledge, D.K., Smith, B.G., Wilson, R.F. The Journal of prosthetic dentistry. (1994) [Pubmed]
  31. Enamel pitting: a common symptom of tuberous sclerosis. Mlynarczyk, G. Oral Surg. Oral Med. Oral Pathol. (1991) [Pubmed]
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