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Chemical Compound Review

Lentysine     (2R,3R)-4-(6-aminopurin-9- yl)-2,3...

Synonyms: Lentinacin, Eritadenine, d-eritadenine, SureCN308656, AG-E-70434, ...
 
 
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Disease relevance of d-eritadenine

 

High impact information on d-eritadenine

 

Chemical compound and disease context of d-eritadenine

 

Biological context of d-eritadenine

  • In this study, the time-dependent effects of dietary eritadenine on several variables concerning lipid metabolism were investigated in rats to clarify the sequence of metabolic changes caused by eritadenine, with special interest in the association of the liver microsomal phospholipid profile and the activity of Delta6-desaturase [7].
 

Associations of d-eritadenine with other chemical compounds

 

Gene context of d-eritadenine

References

  1. Dietary eritadenine suppresses guanidinoacetic Acid-induced hyperhomocysteinemia in rats. Fukada, S., Setoue, M., Morita, T., Sugiyama, K. J. Nutr. (2006) [Pubmed]
  2. Hypocholesterolemic action of eritadenine is mediated by a modification of hepatic phospholipid metabolism in rats. Sugiyama, K., Akachi, T., Yamakawa, A. J. Nutr. (1995) [Pubmed]
  3. Disposition of homocysteine in rat hepatocytes and in nontransformed and malignant mouse embryo fibroblasts following exposure to inhibitors of S-adenosylhomocysteine catabolism. Svardal, A.M., Djurhuus, R., Refsum, H., Ueland, P.M. Cancer Res. (1986) [Pubmed]
  4. Inhibition of S-adenosylhomocysteine hydrolase by acyclic sugar adenosine analogue D-eritadenine. Crystal structure of S-adenosylhomocysteine hydrolase complexed with D-eritadenine. Huang, Y., Komoto, J., Takata, Y., Powell, D.R., Gomi, T., Ogawa, H., Fujioka, M., Takusagawa, F. J. Biol. Chem. (2002) [Pubmed]
  5. Dietary eritadenine and ethanolamine depress fatty acid desaturase activities by increasing liver microsomal phosphatidylethanolamine in rats. Shimada, Y., Morita, T., Sugiyama, K. J. Nutr. (2003) [Pubmed]
  6. Suppression of methionine-induced hyperhomocysteinemia by dietary eritadenine in rats. Sekiya, A., Fukada, S., Morita, T., Kawagishi, H., Sugiyama, K. Biosci. Biotechnol. Biochem. (2006) [Pubmed]
  7. Effects of dietary eritadenine on the liver microsomal Delta6-desaturase activity and its mRNA in rats. Shimada, Y., Yamakawa, A., Morita, T., Sugiyama, K. Biosci. Biotechnol. Biochem. (2003) [Pubmed]
  8. Effects of dietary eritadenine on delta6-desaturase activity and fatty acid profiles of several lipids in rats fed different fats. Shimada, Y., Morita, T., Sugiyama, K. Biosci. Biotechnol. Biochem. (2002) [Pubmed]
  9. Eritadenine: a new tool for investigation of the adenosine P site in plasma membranes of rat fat cells. Söchtig, E., Trost, T. Pharmacology (1981) [Pubmed]
 
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