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Chemical Compound Review

iofetamine     1-(4-iodophenyl)-N-propan-2- yl-propan-2-amine

Synonyms: Iodine-123-IMP, CHEMBL1201308, SureCN1534301, CCG-204779, Lopac0_000694, ...
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Disease relevance of iofetamine


Psychiatry related information on iofetamine


High impact information on iofetamine


Anatomical context of iofetamine


Gene context of iofetamine


Analytical, diagnostic and therapeutic context of iofetamine


  1. Increased iofetamine I 123 brain uptake in metastatic melanoma. Nagel, J.S., Ichise, M., Mueller, S.P., Johnson, K.A., English, R.J., Kaplan, W.D., Schober, O., Holman, B.L. Arch. Neurol. (1988) [Pubmed]
  2. Increased accumulation of N-isopropyl-(I-123)p-iodoamphetamine in bronchial carcinoid tumor. Nishizawa, S., Higa, T., Kuroda, Y., Sano, A., Murakami, M., Takahashi, Y. J. Nucl. Med. (1990) [Pubmed]
  3. Early and delayed SPECT using N-isopropyl p-iodoamphetamine iodine 123 in cerebral ischemia. A prognostic index for clinical recovery. Defer, G., Moretti, J.L., Cesaro, P., Sergent, A., Raynaud, C., Degos, J.D. Arch. Neurol. (1987) [Pubmed]
  4. Iofetamine I 123 single photon emission computed tomography is accurate in the diagnosis of Alzheimer's disease. Johnson, K.A., Holman, B.L., Rosen, T.J., Nagel, J.S., English, R.J., Growdon, J.H. Arch. Intern. Med. (1990) [Pubmed]
  5. I-123 iofetamine single-photon computed emission tomography in rapid cycling bipolar disorder: a clinical study. Gyulai, L., Alavi, A., Broich, K., Reilley, J., Ball, W.B., Whybrow, P.C. Biol. Psychiatry (1997) [Pubmed]
  6. Single photon emission computed tomography in Alzheimer's disease. Abnormal iofetamine I 123 uptake reflects dementia severity. Johnson, K.A., Holman, B.L., Mueller, S.P., Rosen, T.J., English, R., Nagel, J.S., Growdon, J.H. Arch. Neurol. (1988) [Pubmed]
  7. Cognitive deterioration associated with focal cortical dysplasia. Oki, J., Miyamoto, A., Takahashi, S., Takei, H. Pediatric neurology. (1999) [Pubmed]
  8. Acetazolamide challenge and technetium-99m-ECD versus iodine-123-IMP SPECT in chronic occlusive cerebrovascular disease. Ohnishi, T., Yano, T., Nakano, S., Jinnouchi, S., Nagamachi, S., Flores, L.I., Nakahara, H., Watanabe, K. J. Nucl. Med. (1997) [Pubmed]
  9. Functional mapping of flow and back-diffusion rate of N-isopropyl-p-iodoamphetamine in human brain. Yonekura, Y., Nishizawa, S., Mukai, T., Iwasaki, Y., Fukuyama, H., Ishikawa, M., Tamaki, N., Konishil, J. J. Nucl. Med. (1993) [Pubmed]
  10. A noninvasive procedure for in vivo assay of a lung amine endothelial receptor. Touya, J.J., Rahimian, J., Grubbs, D.E., Corbus, H.F., Bennett, L.R. J. Nucl. Med. (1985) [Pubmed]
  11. A new brain perfusion imaging agent: [I-123]HIPDM:N,N,N'-trimethyl-N'-[2-hydroxy-3-methyl-5-iodobenzyl]-1,3-propanediamine. Kung, H.F., Tramposch, K.M., Blau, M. J. Nucl. Med. (1983) [Pubmed]
  12. Dual-isotope autoradiographic measurement of regional blood flow and benzodiazepine receptor availability following unilateral middle cerebral artery occlusion. al-Tikriti, M.S., Dey, H.M., Zoghbi, S.S., Baldwin, R.M., Zea-Ponce, Y., Innis, R.B. European journal of nuclear medicine. (1994) [Pubmed]
  13. Serotonin uptake in cerebral cortex cultures: imipramine-like inhibition by N-isopropyl-p-iodoamphetamine. de Jong, B.M., Feenstra, M.G., Ruijter, J.M., van Royen, E.A. Exp. Neurol. (1989) [Pubmed]
  14. Metabolism in vitro of radioiodinated N-isopropyl-p-iodoamphetamine by isolated hepatocytes. Moerlein, S.M., Weisman, R.A., Beck, D., Li, A.P., Welch, M.J. Nucl. Med. Biol. (1993) [Pubmed]
  15. Temporal lobe asymmetry with iofetamine (IMP) SPECT imaging in patients with major depression. Amsterdam, J.D., Mozley, P.D. Journal of affective disorders. (1992) [Pubmed]
  16. Caudate nucleus infarction demonstrated by N-isopropyl-p iodoamphetamine SPECT imaging using a rotating gamma camera. Polak, J.F., Mueller, S.P., Holman, B.L. Clinical nuclear medicine. (1986) [Pubmed]
  17. I-123 iofetamine SPECT scan in systemic lupus erythematosus patients with cognitive and other minor neuropsychiatric symptoms: a pilot study. Rogers, M.P., Waterhouse, E., Nagel, J.S., Roberts, N.W., Stern, S.H., Fraser, P., Partridge, R., Murawski, B., Khoshbin, S., Holman, B.L. Lupus (1992) [Pubmed]
  18. A double-radionuclide autoradiographic method using N-isopropyl-iodoamphetamine for sequential measurements of local cerebral blood flow. Obrenovitch, T.P., Clayton, C.B., Strong, A.J. J. Cereb. Blood Flow Metab. (1987) [Pubmed]
  19. Cerebral perfusion in progressive supranuclear palsy. Johnson, K.A., Sperling, R.A., Holman, B.L., Nagel, J.S., Growdon, J.H. J. Nucl. Med. (1992) [Pubmed]
  20. Effect of antidepressant and narcoleptic drugs on N-isopropyl p-iodoamphetamine biodistribution in animals. Moretti, J.L., Holman, B.L., Delmon, L., Carmel, A., Johnson, D., Moingeon, P., Blau, M. J. Nucl. Med. (1987) [Pubmed]
  21. Effects of visual stimulation on the redistribution of iodine-123-IMP in the brain using SPECT imaging. Weber, D.A., Cabahug, C., Klieger, P., Volkow, N.D., Wong, C., Sacker, D., Ivanovic, M. J. Nucl. Med. (1991) [Pubmed]
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