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MeSH Review

Parietal Lobe

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Disease relevance of Parietal Lobe


Psychiatry related information on Parietal Lobe

  • Reaction time costs plus benefits were correlated with right-left asymmetry in resting levels of cerebral glucose metabolism in the superior parietal lobe for DAT patients but not for controls [6].
  • These results are rather unexpected but are consistent with other data (e.g. the clinical parietal lobe syndrome and focus of glucose hypometabolism in Alzheimer's disease) [7].
  • Degree of impairment was related to Glascow Coma Scale score, length of posttraumatic amnesia, reduced visuospatial and memory abilities, and the presence of intracranial pathology of the parietal lobes [8].

High impact information on Parietal Lobe

  • RESULTS: Deficit patients performed more poorly than nondeficit patients on two frontal lobe measures, the Stroop Color-Word Interference and Trails Making B tests, and one parietal lobe measure, the Mooney Faces Closure Test. There were no differences in performance on the temporal lobe measures between the two groups [9].
  • Parietal lobe epilepsy: diagnostic considerations and results of surgery [10].
  • Biopsy-proved Alzheimer disease presenting as a right parietal lobe syndrome [11].
  • More transparent Spanish words yielded greater activity in superior temporal gyrus (STG; BA 22), a region implicated in phonological processing, and orthographically opaque English words yielded greater activity in visual processing and word recoding regions, such as the occipito-parietal border and inferior parietal lobe (IPL; BA 40) [12].
  • Although mild perfusion defect was also detected in 4 (19.0%) of the patients with non-CNS-SLE, it only involved a single region and spared the frontal and parietal lobes [13].

Chemical compound and disease context of Parietal Lobe


Biological context of Parietal Lobe


Anatomical context of Parietal Lobe


Associations of Parietal Lobe with chemical compounds

  • Lesions involved the superior temporal gyrus (including the planum temporale), the inferior parietal lobe and the parietal operculum; this area appears to constitute the human auditory cortical processing area [21].
  • In all subjects, verbal competency generally correlated with metabolic activity in the left frontal and temporal areas, while visuo-constructive test performance was linked to glucose utilization in the right parietal lobe [22].
  • Women with TS had a significantly lower parietal lobe concentration of N-acetyl aspartate, and higher hippocampal choline [23].
  • MRS of the frontal and parietal lobes showed no differences in the N-acetyl aspartate/creatine or N-acetyl aspartate/choline ratios between groups A and B. Patients with cortical atrophy showed a nonsignificant trend toward reduced performance on Rapid Visual Information Processing [24].
  • Selective reduction of N-acetylaspartate in medial temporal and parietal lobes in AD [25].

Gene context of Parietal Lobe


Analytical, diagnostic and therapeutic context of Parietal Lobe


  1. Grey and white matter flumazenil binding in neocortical epilepsy with normal MRI. A PET study of 44 patients. Hammers, A., Koepp, M.J., Richardson, M.P., Hurlemann, R., Brooks, D.J., Duncan, J.S. Brain (2003) [Pubmed]
  2. Unilateral visual neglect and wave P 300. A study of nine cases with unilateral lesions of the parietal lobes. Lhermitte, F., Turell, E., LeBrigand, D., Chain, F. Arch. Neurol. (1985) [Pubmed]
  3. An angiographically occult arteriovenous malformation in the medial parietal lobe presenting as seizures of medial temporal lobe origin. Fujii, M., Akimura, T., Ozaki, S., Kato, S., Ito, H., Neshige, R. Epilepsia (1999) [Pubmed]
  4. Interrelationship between beta-amyloid deposition and complement-activated oligodendroglia. Yamada, T., Tsuboi, Y., Takahashi, M. Dementia and geriatric cognitive disorders. (1997) [Pubmed]
  5. Auditory brainstem response versus magnetic resonance imaging for the evaluation of asymmetric sensorineural hearing loss. Cueva, R.A. Laryngoscope (2004) [Pubmed]
  6. Visuospatial attention in dementia of the Alzheimer type. Parasuraman, R., Greenwood, P.M., Haxby, J.V., Grady, C.L. Brain (1992) [Pubmed]
  7. Regional weight loss of the cerebral cortex and some subcortical nuclei in senile dementia of the Alzheimer type. Najlerahim, A., Bowen, D.M. Acta Neuropathol. (1988) [Pubmed]
  8. Astereopsis caused by traumatic brain injury. Miller, L.J., Mittenberg, W., Carey, V.M., McMorrow, M.A., Kushner, T.E., Weinstein, J.M. Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists. (1999) [Pubmed]
  9. Neuropsychological impairments in deficit vs nondeficit forms of schizophrenia. Buchanan, R.W., Strauss, M.E., Kirkpatrick, B., Holstein, C., Breier, A., Carpenter, W.T. Arch. Gen. Psychiatry (1994) [Pubmed]
  10. Parietal lobe epilepsy: diagnostic considerations and results of surgery. Williamson, P.D., Boon, P.A., Thadani, V.M., Darcey, T.M., Spencer, D.D., Spencer, S.S., Novelly, R.A., Mattson, R.H. Ann. Neurol. (1992) [Pubmed]
  11. Biopsy-proved Alzheimer disease presenting as a right parietal lobe syndrome. Crystal, H.A., Horoupian, D.S., Katzman, R., Jotkowitz, S. Ann. Neurol. (1982) [Pubmed]
  12. Impact of language proficiency and orthographic transparency on bilingual word reading: an fMRI investigation. Meschyan, G., Hernandez, A.E. Neuroimage (2006) [Pubmed]
  13. Diagnostic value of single-photon-emission computed tomography in severe central nervous system involvement of systemic lupus erythematosus: a case-control study. Zhang, X., Zhu, Z., Zhang, F., Shu, H., Li, F., Dong, Y. Arthritis Rheum. (2005) [Pubmed]
  14. Differentiation of benign vs. malignant mass in a postirradiation cerebral arteriovenous malformation by 2-deoxy-2-[18F] fluoro-D-glucose positron emission tomography. Raman, A., Rothrock, J.F., Liu, H.G., Mountz, J.M. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging. (2004) [Pubmed]
  15. Epilepsy in schizencephaly: abnormal cortical organization studied by somatosensory evoked potentials. Vossler, D.G., Wilkus, R.J., Pilcher, W.H., Farwell, J.R. Epilepsia (1992) [Pubmed]
  16. A fenfluramine-activated FDG-PET study of borderline personality disorder. Soloff, P.H., Meltzer, C.C., Greer, P.J., Constantine, D., Kelly, T.M. Biol. Psychiatry (2000) [Pubmed]
  17. Reduced size of corpus callosum in autism. Egaas, B., Courchesne, E., Saitoh, O. Arch. Neurol. (1995) [Pubmed]
  18. Cutaneous mechanical sensory stimulation increases extracellular acetylcholine release in cerebral cortex in anesthetized rats. Kurosawa, M., Sato, A., Sato, Y. Neurochem. Int. (1992) [Pubmed]
  19. Tissue distribution and species difference of the brain type glucose transporter (GLUT3). Yano, H., Seino, Y., Inagaki, N., Hinokio, Y., Yamamoto, T., Yasuda, K., Masuda, K., Someya, Y., Imura, H. Biochem. Biophys. Res. Commun. (1991) [Pubmed]
  20. Fluoxetine effects on cerebral glucose metabolism. Cook, E.H., Metz, J., Leventhal, B.L., Lebovitz, M., Nathan, M., Semerdjian, S.A., Brown, T., Cooper, M.D. Neuroreport (1994) [Pubmed]
  21. Non-verbal environmental sound recognition after unilateral hemispheric stroke. Schnider, A., Benson, D.F., Alexander, D.N., Schnider-Klaus, A. Brain (1994) [Pubmed]
  22. Alzheimer's disease: focal cortical changes shown by positron emission tomography. Foster, N.L., Chase, T.N., Fedio, P., Patronas, N.J., Brooks, R.A., Di Chiro, G. Neurology (1983) [Pubmed]
  23. Influence of X chromosome and hormones on human brain development: a magnetic resonance imaging and proton magnetic resonance spectroscopy study of Turner syndrome. Cutter, W.J., Daly, E.M., Robertson, D.M., Chitnis, X.A., van Amelsvoort, T.A., Simmons, A., Ng, V.W., Williams, B.S., Shaw, P., Conway, G.S., Skuse, D.H., Collier, D.A., Craig, M., Murphy, D.G. Biol. Psychiatry (2006) [Pubmed]
  24. Brain abnormalities demonstrated by magnetic resonance imaging in adult IDDM patients with and without a history of recurrent severe hypoglycemia. Perros, P., Deary, I.J., Sellar, R.J., Best, J.J., Frier, B.M. Diabetes Care (1997) [Pubmed]
  25. Selective reduction of N-acetylaspartate in medial temporal and parietal lobes in AD. Schuff, N., Capizzano, A.A., Du, A.T., Amend, D.L., O'Neill, J., Norman, D., Kramer, J., Jagust, W., Miller, B., Wolkowitz, O.M., Yaffe, K., Weiner, M.W. Neurology (2002) [Pubmed]
  26. Early diagnosis of Alzheimer disease with positron emission tomography. Jelic, V., Nordberg, A. Alzheimer disease and associated disorders. (2000) [Pubmed]
  27. Atypical motor and sensory cortex activation in attention-deficit/hyperactivity disorder: a functional magnetic resonance imaging study of simple sequential finger tapping. Mostofsky, S.H., Rimrodt, S.L., Schafer, J.G., Boyce, A., Goldberg, M.C., Pekar, J.J., Denckla, M.B. Biol. Psychiatry (2006) [Pubmed]
  28. Patterns of brain activity during visual imagery of letters. Raij, T. Journal of cognitive neuroscience. (1999) [Pubmed]
  29. Children and adolescents with velocardiofacial syndrome: a volumetric MRI study. Eliez, S., Schmitt, J.E., White, C.D., Reiss, A.L. The American journal of psychiatry. (2000) [Pubmed]
  30. Expression of the CRE-BP1 transcriptional regulator binding to the cyclic AMP response element in central nervous system, regenerating liver, and human tumors. Takeda, J., Maekawa, T., Sudo, T., Seino, Y., Imura, H., Saito, N., Tanaka, C., Ishii, S. Oncogene (1991) [Pubmed]
  31. Abnormal regional cerebral blood flow on 99mTc ECD brain SPECT in patients with primary Sjögren's syndrome and normal findings on brain magnetic resonance imaging. Chang, C.P., Shiau, Y.C., Wang, J.J., Ho, S.T., Kao, A. Ann. Rheum. Dis. (2002) [Pubmed]
  32. Regional cerebral glucose metabolism and blood flow in a patient with Marchiafava-Bignami disease. Ishii, K., Ikerjiri, Y., Sasaki, M., Kitagaki, H., Mori, E. AJNR. American journal of neuroradiology. (1999) [Pubmed]
  33. Well-maintained responses of acetylcholine release and blood flow in the cerebral cortex to focal electrical stimulation of the nucleus basalis of Meynert in aged rats. Kurosawa, M., Sato, A., Sato, Y. Neurosci. Lett. (1989) [Pubmed]
  34. A case of parietal lobe epilepsy with distinctive clinical and neuroradiological features. Oka, A., Kubota, M., Sakakihara, Y., Yanagisawa, M. Brain Dev. (1998) [Pubmed]
  35. Aspergillosis of the CNS in a pediatric liver transplant recipient: case report and review. Green, M., Wald, E.R., Tzakis, A., Todo, S., Starzl, T.E. Rev. Infect. Dis. (1991) [Pubmed]
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