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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

Glucobay     (3R,4R,5S,6R)-5- [(2S,3R,4R,5S,6R)-5-[(2R...

Synonyms: Acarbosa, acarbose, Acarbosum, Precose, Precose (TN), ...
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Analytical, diagnostic and therapeutic context of acarbose


  1. A glycoside-hydrolase inhibitor in treatment of dumping syndrome. McLoughlin, J.C., Buchanan, K.D., Alam, M.J. Lancet (1979) [Pubmed]
  2. Multicenter, placebo-controlled trial comparing acarbose (BAY g 5421) with placebo, tolbutamide, and tolbutamide-plus-acarbose in non-insulin-dependent diabetes mellitus. Coniff, R.F., Shapiro, J.A., Seaton, T.B., Bray, G.A. Am. J. Med. (1995) [Pubmed]
  3. Effect of acarbose (BAY-g-5421) on expression of noninsulin-dependent diabetes mellitus in sucrose-fed SHR/N-corpulent rats. Carswell, N., Michaelis, O.E., Prather, E.S. J. Nutr. (1989) [Pubmed]
  4. Do carbohydrates promote hypertension? Fagerberg, B. International journal of obesity. (1981) [Pubmed]
  5. Reduction of carbohydrate-induced hypertriglyceridemia in (fa,fa) "Zucker" rats by the alpha-glucosidase inhibitor acarbose (BAY g 5421). Krause, H.P., Keup, U., Thomas, G., Puls, W. Metab. Clin. Exp. (1982) [Pubmed]
  6. The effects of conjugated linoleic acids or an alpha-glucosidase inhibitor on tissue lipid concentrations and fatty acid composition of broiler chicks fed a low-protein diet. Aletor, V.A., Eder, K., Becker, K., Paulicks, B.R., Roth, F.X., Roth-Maier, D.A. Poult. Sci. (2003) [Pubmed]
  7. Effects of acarbose (Glucobay) in persons with type 1 diabetes: a multicentre study. Sels, J.P., Verdonk, H.E., Wolffenbuttel, B.H. Diabetes Res. Clin. Pract. (1998) [Pubmed]
  8. Effect of a glucosidase inhibitor on the metabolic response of diabetic rats to a high carbohydrate diet, consisting of starch and sucrose, or glucose. Gray, R.S., Olefsky, J.M. Metab. Clin. Exp. (1982) [Pubmed]
  9. Effect of acarbose and simultaneous antacid therapy on blood glucose. Höpfner, M., Durani, B., Spengler, M., Fölsch, U.R. Arzneimittel-Forschung. (1997) [Pubmed]
  10. Prefeeding-dependent anaerobic metabolization of xenobiotics by intestinal bacteria--methods for acarbose metabolites in an artificial colon. Pfeffer, M., Siebert, G. Zeitschrift für Ernährungswissenschaft. (1986) [Pubmed]
  11. Beneficial effects on serum lipids in noninsulin dependent diabetics by acarbose treatment. Leonhardt, W., Hanefeld, M., Fischer, S., Schulze, J., Spengler, M. Arzneimittel-Forschung. (1991) [Pubmed]
  12. The effects of the alpha-glucosidase inhibitor BAY g 5421 (Acarbose) on postprandial blood glucose, serum insulin, and triglyceride levels: dose-time-response relationships in man. Hillebrand, I., Boehme, K., Frank, G., Fink, H., Berchtold, P. Research in experimental medicine. Zeitschrift für die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie. (1979) [Pubmed]
  13. Isolation and structural elucidation of biotransformation products from acarbose. Boberg, M., Kurz, J., Ploschke, H.J., Schmitt, P., Scholl, H., Schüller, M., Wünsche, C. Arzneimittel-Forschung. (1990) [Pubmed]
  14. Lysosomal glycogen storage mimicking the cytological picture of Pompe's disease as induced in rats by injection of an alpha-glucosidase inhibitor. I. Alterations in liver. Lüllmann-Rauch, R. Virchows Arch., B, Cell Pathol. (1981) [Pubmed]
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