Chemical Compound Review:
Tocris-1237 4-[(S)-amino-carboxy-methyl]- 3-methyl...
Synonyms:
AC1NSKBK, CHEMBL94631, SureCN661700, CHEBI:252690, LY-367385, ...
Kingston,
O'Neill,
Bond,
Bruno,
Battaglia,
Nicoletti,
Harris,
Clark,
Monn,
Lodge,
Schoepp,
Baskys,
Bayazitov,
Fang,
Blaabjerg,
Poulsen,
Zimmer,
Heinbockel,
Laaris,
Ennis,
Kingston,
Griffey,
Johnson,
Chamberlain,
Kelly,
Tomlinson,
Wright,
Johnson,
Schoepp,
Harris,
Clark,
Baker,
Tizzano,
Ireland,
Abraham,
Turner,
Salt,
Pisani,
Gubellini,
Bonsi,
Conquet,
Picconi,
Centonze,
Bernardi,
Calabresi,
- Selective blockade of type-1 metabotropic glutamate receptors induces neuroprotection by enhancing gabaergic transmission. Battaglia, G., Bruno, V., Pisani, A., Centonze, D., Catania, M.V., Calabresi, P., Nicoletti, F. Mol. Cell. Neurosci. (2001)
- Neuroprotective actions of novel and potent ligands of group I and group II metabotropic glutamate receptors. Kingston, A.E., O'Neill, M.J., Bond, A., Bruno, V., Battaglia, G., Nicoletti, F., Harris, J.R., Clark, B.P., Monn, J.A., Lodge, D., Schoepp, D.D. Ann. N. Y. Acad. Sci. (1999)
- Antidepressant-like effects of baclofen and LY367385 in the forced swim test in rats. Car, H., Wi??niewskao, R.J. Pharmacological reports : PR (2006)
- Pharmacological antagonism of metabotropic glutamate receptor 1 regulates long-term potentiation and spatial reference memory in the dentate gyrus of freely moving rats via N-methyl-D-aspartate and metabotropic glutamate receptor-dependent mechanisms. Naie, K., Manahan-Vaughan, D. Eur. J. Neurosci. (2005)
- Agonist-independent internalization of metabotropic glutamate receptor 1a is arrestin- and clathrin-dependent and is suppressed by receptor inverse agonists. Pula, G., Mundell, S.J., Roberts, P.J., Kelly, E. J. Neurochem. (2004)
- Group I metabotropic glutamate receptors (mGluRs) modulate visual responses in the superficial superior colliculus of the rat. Cirone, J., Pothecary, C.A., Turner, J.P., Salt, T.E. J. Physiol. (Lond.) (2002)
- Olfactory nerve stimulation-evoked mGluR1 slow potentials, oscillations, and calcium signaling in mouse olfactory bulb mitral cells. Yuan, Q., Knöpfel, T. J. Neurophysiol. (2006)
- Group I metabotropic glutamate receptors reduce excitotoxic injury and may facilitate neurogenesis. Baskys, A., Bayazitov, I., Fang, L., Blaabjerg, M., Poulsen, F.R., Zimmer, J. Neuropharmacology (2005)
- Synaptic activation of the group I metabotropic glutamate receptor mGlu1 on the thalamocortical neurons of the rat dorsal lateral geniculate nucleus in vitro. Turner, J.P., Salt, T.E. Neuroscience (2000)
- Inhibition of group I metabotropic glutamate receptor responses in vivo in rats by a new generation of carboxyphenylglycine-like amino acid antagonists. Kingston, A.E., Griffey, K., Johnson, M.P., Chamberlain, M.J., Kelly, G., Tomlinson, R., Wright, R.A., Johnson, B.G., Schoepp, D.D., Harris, J.R., Clark, B.P., Baker, R.S., Tizzano, J.T. Neurosci. Lett. (2002)
- Group I metabotropic glutamate receptor antagonists block secondary thermal hyperalgesia in rats with knee joint inflammation. Zhang, L., Lu, Y., Chen, Y., Westlund, K.N. J. Pharmacol. Exp. Ther. (2002)
- Metabotropic glutamate receptors 1 and 5 differentially regulate CA1 pyramidal cell function. Mannaioni, G., Marino, M.J., Valenti, O., Traynelis, S.F., Conn, P.J. J. Neurosci. (2001)
- Metabotropic glutamate receptor 5 mediates the potentiation of N-methyl-D-aspartate responses in medium spiny striatal neurons. Pisani, A., Gubellini, P., Bonsi, P., Conquet, F., Picconi, B., Centonze, D., Bernardi, G., Calabresi, P. Neuroscience (2001)
- Group I mGluRs increase excitability of hippocampal CA1 pyramidal neurons by a PLC-independent mechanism. Ireland, D.R., Abraham, W.C. J. Neurophysiol. (2002)
- Metabotropic glutamate receptors in the main olfactory bulb drive granule cell-mediated inhibition. Heinbockel, T., Laaris, N., Ennis, M. J. Neurophysiol. (2007)
- Metabotropic glutamate receptor involvement in phosphoinositide hydrolysis stimulation by an endogenous Na(+), K(+)-ATPase inhibitor and ouabain in neonatal rat brain. Calviño, M.A., Peña, C., Rodríguez de Lores Arnaiz, G. Brain Res. Dev. Brain Res. (2002)
- Presynaptic group I metabotropic glutamate receptors modulate synaptic transmission in the rat superior colliculus via 4-AP sensitive K(+) channels. White, A.M., Kylänpää, R.A., Christie, L.A., McIntosh, S.J., Irving, A.J., Platt, B. Br. J. Pharmacol. (2003)
- Down-regulation of metabotropic glutamate receptor 1alpha in globus pallidus and substantia nigra of parkinsonian monkeys. Kaneda, K., Tachibana, Y., Imanishi, M., Kita, H., Shigemoto, R., Nambu, A., Takada, M. Eur. J. Neurosci. (2005)