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Chemical Compound Review

Rubidazon     N-[1-[(2S,4S)-4-(4-amino-5- hydroxy-6...

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Disease relevance of Rubidazon


High impact information on Rubidazon


Chemical compound and disease context of Rubidazon


Biological context of Rubidazon


Anatomical context of Rubidazon


Associations of Rubidazon with other chemical compounds


Gene context of Rubidazon

  • Chronic treatment with these anthracyclines also resulted in significantly less cardiomyopathy, especially in the case of N-L-leucyl-daunorubicin and rubidazone [20].

Analytical, diagnostic and therapeutic context of Rubidazon


  1. Myelofibrosis associated with rubidazone. Cheng, D.S., Eyre, H.J. Lancet (1978) [Pubmed]
  2. The effectiveness of rubidazone in hairy cell leukemia (leukemic reticuloendotheliosis). Stewart, D.J., Benjamin, R.S., McCredie, K.B., Murphy, S., Keating, M. Blood (1979) [Pubmed]
  3. Phase 1 trial and assay of rubidazone (NSC 164011) in patients with advanced solid tumors. Kovach, J.S., Ames, M.M., Sternad, M.L., O'Connell, M.J. Cancer Res. (1979) [Pubmed]
  4. Kinetic response to cultured human lymphoid cells to rubidazone. Barlogie, B., Drewinko, B., Benjamin, R.S. J. Natl. Cancer Inst. (1978) [Pubmed]
  5. A randomized trial of amsacrine and rubidazone in 39 patients with acute promyelocytic leukemia. Fenaux, P., Tertian, G., Castaigne, S., Tilly, H., Leverger, G., Guy, H., Bordessoule, D., Leblay, R., Le Gall, E., Colombat, P. J. Clin. Oncol. (1991) [Pubmed]
  6. Transport and binding of daunorubicin, adriamycin, and rubidazone in Ehrlich ascites tumour cells. Skovsgaard, T. Biochem. Pharmacol. (1977) [Pubmed]
  7. Combination of rubidazone and cytosine arabinoside in the treatment of first relapse in acute myelocytic leukemia. Pavlovsky, S., Fernández, I., Palau, V., Santarelli, M.T., De Bellis, R., Ruiz-Argüelles, G., Brandalise, S., Jiménez-Fonseca, E. Ann. Oncol. (1991) [Pubmed]
  8. Randomized phase II trial of rubidazone and adriamycin in women with advanced breast cancer. Ingle, J.N., Ahmann, D.L., O'Fallon, J.R., Bisel, H.F., Rubin, J., Kvols, L.K., Giuliani, E.R. Cancer treatment reports. (1979) [Pubmed]
  9. Development of resistance to rubidazone (NSC-164011) in Ehrlich ascites tumor in vivo. Skovsgaard, T. Cancer chemotherapy reports. Part 1. (1975) [Pubmed]
  10. Cardiac toxicity of adriamycin-DNA complex and rubidazone: evaluation by electrocardiogram and endomyocardial biopsy. Benjamin, R.S., Mason, J.W., Billingham, M.E. Cancer treatment reports. (1978) [Pubmed]
  11. Model systems for cardiotoxic effects of anthracyclines. Zbinden, G., Bachmann, E., Holderegger, C. Antibiotics and chemotherapy. (1978) [Pubmed]
  12. Anthracycline-induced histamine release from rat mast cells. Riegel, E.A., Kaliner, M., El-Hage, A.N., Ferrans, V.J., Kawanami, O., Herman, E.H. Agents Actions (1982) [Pubmed]
  13. Mechanism of anthraquinone-induced calcium release from skeletal muscle sarcoplasmic reticulum. Abramson, J.J., Buck, E., Salama, G., Casida, J.E., Pessah, I.N. J. Biol. Chem. (1988) [Pubmed]
  14. Distribution and metabolism of rubidazone and daunorubicin in mice. Baurain, R., Deprez-De Campeneere, D., Trouet, A. Cancer Chemother. Pharmacol. (1979) [Pubmed]
  15. Clinical trial of rubidazone in advanced squamous cell carcinoma of the lung and adenocarcinoma of the large intestine. Fraile, R.J., Samson, M.K., Buroker, T.R., O'Bryan, R., Baker, L.H., Vaitkevicius, V.K. Cancer treatment reports. (1978) [Pubmed]
  16. Antitumor anthracycline antibiotics. Structure-activity and structure-cardiotoxicity relationships of rubidazone analogues. Tong, G.L., Cory, M., Lee, W.W., Henry, D.W. J. Med. Chem. (1978) [Pubmed]
  17. A four-year experience with anthracycline, cytosine arabinoside, vincristine and prednisone combination chemotherapy in 325 adults with acute leukemia. Keating, M.J., Smith, T.L., McCredie, K.B., Bodey, G.P., Hersh, E.M., Gutterman, J.U., Gehan, E., Freireich, E.J. Cancer (1981) [Pubmed]
  18. Induction of high frequencies of endoreduplication in mammalian cell cultures with 33258 Hoechst and rubidazone. Kusyk, C.J., Hsu, T.C. Cytogenet. Cell Genet. (1979) [Pubmed]
  19. Treatment of adult acute lymphoblastic leukemia. Preliminary results of a trial from the French Group. Fière, D., Archimbaud, E., Extra, J.M., Marty, M., David, B., Witz, F., Sotto, J.J., Rochant, H., Gastaut, J.A., Le Prise, P.Y. Haematology and blood transfusion. (1987) [Pubmed]
  20. Cardiotoxicity and comparative pharmacokinetics of six anthracyclines in the rabbit. Jaenke, R.S., Deprez-DeCampeneere, D., Trouet, A. Cancer Res. (1980) [Pubmed]
  21. Determination of rubidazone and its metabolites in human plasma and urine by reversed-phase ion-pair high-performance liquid chromatography. Nguyen-Huu, J.J., Turk, P., Diquet, B. J. Chromatogr. (1986) [Pubmed]
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