Gene Review:
GPR132 - G protein-coupled receptor 132
Homo sapiens
Synonyms:
G2 accumulation protein, G2A
- Lysophosphatidylcholine as a ligand for the immunoregulatory receptor G2A. Kabarowski, J.H., Zhu, K., Le, L.Q., Witte, O.N., Xu, Y. Science (2001)
- Human immunodeficiency virus type 1 cell cycle control: Vpr is cytostatic and mediates G2 accumulation by a mechanism which differs from DNA damage checkpoint control. Bartz, S.R., Rogel, M.E., Emerman, M. J. Virol. (1996)
- Effect of melphalan and hyperthermia on cell cycle progression and cyclin B1 expression in human melanoma cells. Orlandi, L., Zaffaroni, N., Bearzatto, A., Costa, A., Supino, R., Vaglini, M., Silvestrini, R. Cell Prolif. (1995)
- Sequence variability of human cytomegalovirus UL146 and UL147 genes in low-passage clinical isolates. He, R., Ruan, Q., Qi, Y., Ma, Y.P., Huang, Y.J., Sun, Z.R., Ji, Y.H. Intervirology (2006)
- Mn-superoxide dismutase overexpression enhances G2 accumulation and radioresistance in human oral squamous carcinoma cells. Kalen, A.L., Sarsour, E.H., Venkataraman, S., Goswami, P.C. Antioxid. Redox Signal. (2006)
- Therapeutic effects of lysophosphatidylcholine in experimental sepsis. Yan, J.J., Jung, J.S., Lee, J.E., Lee, J., Huh, S.O., Kim, H.S., Jung, K.C., Cho, J.Y., Nam, J.S., Suh, H.W., Kim, Y.H., Song, D.K. Nat. Med. (2004)
- Kinetic response to cultured human lymphoid cells to rubidazone. Barlogie, B., Drewinko, B., Benjamin, R.S. J. Natl. Cancer Inst. (1978)
- Lysophosphatidylcholine as a ligand for immunoregulation. Kabarowski, J.H., Xu, Y., Witte, O.N. Biochem. Pharmacol. (2002)
- A DNA damage and stress inducible G protein-coupled receptor blocks cells in G2/M. Weng, Z., Fluckiger, A.C., Nisitani, S., Wahl, M.I., Le, L.Q., Hunter, C.A., Fernal, A.A., Le Beau, M.M., Witte, O.N. Proc. Natl. Acad. Sci. U.S.A. (1998)
- The lysophospholipid receptor G2A activates a specific combination of G proteins and promotes apoptosis. Lin, P., Ye, R.D. J. Biol. Chem. (2003)
- Identification of 9-hydroxyoctadecadienoic acid and other oxidized free fatty acids as ligands of the G protein-coupled receptor G2A. Obinata, H., Hattori, T., Nakane, S., Tatei, K., Izumi, T. J. Biol. Chem. (2005)
- G protein-coupled receptors GPR4 and TDAG8 are oncogenic and overexpressed in human cancers. Sin, W.C., Zhang, Y., Zhong, W., Adhikarakunnathu, S., Powers, S., Hoey, T., An, S., Yang, J. Oncogene (2004)
- Positron emission tomography imaging analysis of G2A as a negative modifier of lymphoid leukemogenesis initiated by the BCR-ABL oncogene. Le, L.Q., Kabarowski, J.H., Wong, S., Nguyen, K., Gambhir, S.S., Witte, O.N. Cancer Cell (2002)
- Differential proton sensitivity of related G protein-coupled receptors T cell death-associated gene 8 and G2A expressed in immune cells. Radu, C.G., Nijagal, A., McLaughlin, J., Wang, L., Witte, O.N. Proc. Natl. Acad. Sci. U.S.A. (2005)
- Human resting CD16-, CD16+ and IL-2-, IL-12-, IL-15- or IFN-alpha-activated natural killer cells differentially respond to sphingosylphosphorylcholine, lysophosphatidylcholine and platelet-activating factor. Jin, Y., Damaj, B.B., Maghazachi, A.A. Eur. J. Immunol. (2005)
- G2A is a proton-sensing G-protein-coupled receptor antagonized by lysophosphatidylcholine. Murakami, N., Yokomizo, T., Okuno, T., Shimizu, T. J. Biol. Chem. (2004)
- Receptors for protons or lipid messengers or both? Seuwen, K., Ludwig, M.G., Wolf, R.M. J. Recept. Signal Transduct. Res. (2006)
- The cyclin-dependent kinase inhibitor butyrolactone is a potent inhibitor of p21 (WAF1/CIP1 expression). Sax, J.K., Dash, B.C., Hong, R., Dicker, D.T., El-Deiry, W.S. Cell Cycle (2002)
- The effect of the Fanconi anemia polypeptide, FAC, upon p53 induction and G2 checkpoint regulation. Kupfer, G.M., D'Andrea, A.D. Blood (1996)
- Enhancement of G2 checkpoint function by gelsolin transfection in human cancer cells. Sakai, N., Ohtsu, M., Fujita, H., Koike, T., Kuzumaki, N. Exp. Cell Res. (1999)
- Expression of G2A, a receptor for lysophosphatidylcholine, by macrophages in murine, rabbit, and human atherosclerotic plaques. Rikitake, Y., Hirata, K., Yamashita, T., Iwai, K., Kobayashi, S., Itoh, H., Ozaki, M., Ejiri, J., Shiomi, M., Inoue, N., Kawashima, S., Yokoyama, M. Arterioscler. Thromb. Vasc. Biol. (2002)
- The action mode of lysophosphatidylcholine in human monocytes. Yun, M.R., Okajima, F., Im, D.S. J. Pharmacol. Sci. (2004)
- Quantitative analysis of orphan G protein-coupled receptor mRNAs by TaqMan Real-Time PCR: G2A and GPR4 lysophospholipid receptor expression in leukocytes and in a rat myocardial infarction-heart failure model. Douglas, S.A., Ao, Z., Johns, D.G., Maniscalco, K., Willette, R.N., Sarov-Blat, L., Cogswell, J.P., Seepersaud, S., Murdock, P., Steplewski, K.M., Patel, L. Methods Mol. Biol. (2005)
- Effect of hyperthermia on cyclin B expression in a human glioblastoma cell line. Ohshita, N., Nishizaki, T., Ishihara, H., Ito, H., Murakami, T., Mimura, Y. J. Neurooncol. (1995)