Disease relevance of strontium

• Strontium-85 scintigrams of metastases and normal bone were obtained up to 8 wk postinjection [1].
• Ratios of late to early uptake were found to distinguish osteomalacia from osteoporosis in the models when strontium-85 or barium-131 were used [2].
• Barium-131 may be a clinically useful alternative to strontium-85 in the evaluation of metabolic bone disease due to its shorter half-life and lower radiation dose [2].
• Strontium-85 microspheres were injected into the left atrium after placement of the stenosis to verify that changes in resting blood flow were only minimal [3].
• Strontium-85 uptake in knee joints with osteochondritis dissecans [4].

High impact information on strontium

• At 1.5 hrs postresuscitation, cardiac output and blood flow were determined by using strontium-85 microspheres [5].
• Acid treatment resulted in almost a fivefold increase in the amount of new bone formation, as measured by uptake of strontium-85 into the implants [6].
• Regional blood flow and strontium-85 incorporation rate in the rat hindlimb skeleton [7].
• After a 30-min stabilization period, strontium-85 radiolabelled microspheres (15 +/- 1 micron) were injected to the left ventricle for determination of cardiac output and regional blood flows [8].
• Ocular blood flow was determined using radioactive strontium 85 microspheres after an alkali (sodium hydroxide [NaOH]) burn to the eye [9].

Biological context of strontium

• Host tissue response and heterotopic osteoinduction by composites of demineralized bone matrix and three different substances used as bioresorbable carriers implanted in the abdominal muscles were evaluated by strontium 85 uptake and histology 4 weeks postoperatively in 60 male Wistar rats [10].

Anatomical context of strontium

• Toxoplasma oocysts in cat feces were marked with a tracer amount of strontium-85 (85-SR), and were superficially buried simulating the natural disposal of feces by cats [11].
• We evaluated quantitatively, by uptake of strontium 85, the osteoinductive effect of demineralized bone matrix from newborn, 8-week-old (adolescent), and 8-month-old (adult) male Wistar rats implanted in the abdominal muscles of 8-week-old male Wistar rats [12].
• Strontium-85 in the fetuses of pregnant rats and mice [13].
• Observations on experimental aspergillosis of chorioallantoic membranes confirmed that strontium-85 uptake in aspergillus lesions was directly due to infection by the fungus [14].

Gene context of strontium

• Following an early transient increase, the incorporation of strontium-85 into the fractured bones was impaired after 30 days of CT treatment [15].

Analytical, diagnostic and therapeutic context of strontium

• Myocardial blood flow was measured with the radioactive microspheres method using strontium-85-labeled carbonized spheres [16].
• We evaluated the effect of scleral buckling procedures on uveal blood flow in rabbits by injection of microspheres labeled with strontium 85 [17].
• Comparison of bone graft materials. Part I. New bone formation with autografts and allografts determined by Strontium-85 [18].
• Strontium-85 scintigraphy, surface counting and high-resolution whole-body profiles agreed in showing that in both patients tumour turnover of strontium was very rapid, with a biological half-life of only a few days [19].
• At 1 or 4 hr after treatment, animals were anesthetized and strontium 85-labeled microspheres (25 micrometers diam) were infused into the left ventricle [20].

References