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Chemical Compound Review

Hexanes     hexane

Synonyms: Dipropyl, Hexanen, HEXANE, Heksan, Esani, ...
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Disease relevance of MYRISTIC ACID


Psychiatry related information on MYRISTIC ACID

  • Progressive sensorimotor neuropathy developed in two patients exposed to prolonged (chronic) inhalation of n-hexane (glue sniffing) [6].
  • The effects of the methanolic extract of Radix Angelica Sinensis (Umbellifera) (abbreviated as RAS extract) and n-hexane fraction of RAS extract (RAS(H) fraction) on the various drugs-induced amnesia in rats were studied by using passive avoidance task [7].
  • ZnO whiskers were prepared by a solvothermal process with Zn(OH)4(2-), cetyltrimethylammonium bromide (CTAB), n-amyl alcohol and n-hexane at 140 degrees C. The influence of preparation condition on the morphology of the resultant sample was investigated through change zinc salts, co-surfactants, surfactants, reaction temperature, and reaction time [8].

High impact information on MYRISTIC ACID


Chemical compound and disease context of MYRISTIC ACID


Biological context of MYRISTIC ACID


Anatomical context of MYRISTIC ACID


Associations of MYRISTIC ACID with other chemical compounds


Gene context of MYRISTIC ACID


Analytical, diagnostic and therapeutic context of MYRISTIC ACID

  • Compounds 6 and 12 were found to be major urinary metabolites following oral administration of their dipropyl analogs (2 and 13, respectively) [34].
  • The method consists of extraction of the sample with acidic chloroform, followed by defatting with n-hexane and finally, HPLC determination with fluorometric detection [35].
  • The assay procedure comprises n-hexane extraction from basic plasma and gas chromatography using nitrogen-selective detection [36].
  • A series of novel chiral heterometal tetrahedral clusters have firstly been separated on cellulose tris-(3,5-dimethylphenylcarbamate) stationary phase by high-performance liquid chromatography using n-hexane as the mobile phase containing different alcohols as modifiers [37].
  • Lipophilic antioxidants of serum were extracted with n-hexane from an ethanolic solution of serum subjected to centrifugation [38].


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  9. Isolation and identification of hematopoietic stem cell-stimulating substances from Kampo (Japanese herbal) medicine, Juzen-taiho-to. Hisha, H., Yamada, H., Sakurai, M.H., Kiyohara, H., Li, Y., Yu, C., Takemoto, N., Kawamura, H., Yamaura, K., Shinohara, S., Komatsu, Y., Aburada, M., Ikehara, S. Blood (1997) [Pubmed]
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  11. Temperature and viscosity dependence in the stereoselective formation of the inverted housane for the photochemical nitrogen loss from the deuterium-stereolabeled parent diazabicyclo[2.2.1]hept-2-ene. Adam, W., Grüne, M., Diedering, M., Trofimov, A.V. J. Am. Chem. Soc. (2001) [Pubmed]
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  16. Role of the acrAB locus in organic solvent tolerance mediated by expression of marA, soxS, or robA in Escherichia coli. White, D.G., Goldman, J.D., Demple, B., Levy, S.B. J. Bacteriol. (1997) [Pubmed]
  17. Bacterial formation and metabolism of 6-hydroxyhexanoate: evidence of a potential role for omega-oxidation. Kunz, D.A., Weimer, P.J. J. Bacteriol. (1983) [Pubmed]
  18. Automatic gas chromatographic determination of N-methylcarbamates in milk with electron capture detection. Ballesteros, E., Gallego, M., Valcárcel, M. Anal. Chem. (1993) [Pubmed]
  19. Grand rounds: could occupational exposure to n-hexane and other solvents precipitate visual failure in leber hereditary optic neuropathy? Carelli, V., Franceschini, F., Venturi, S., Barboni, P., Savini, G., Barbieri, G., Pirro, E., La Morgia, C., Valentino, M.L., Zanardi, F., Violante, F.S., Mattioli, S. Environ. Health Perspect. (2007) [Pubmed]
  20. Rat lung and liver microsomal cytochrome P-450 isozymes involved in the hydroxylation of n-hexane. Toftgård, R., Haaparanta, T., Eng, L., Halpert, J. Biochem. Pharmacol. (1986) [Pubmed]
  21. Kinetic study of esterification by immobilized lipase in n-hexane. Chulalaksananukul, W., Condoret, J.S., Delorme, P., Willemot, R.M. FEBS Lett. (1990) [Pubmed]
  22. Glue-sniffing neuropathy. Korobkin, R., Asbury, A.K., Sumner, A.J., Nielsen, S.L. Arch. Neurol. (1975) [Pubmed]
  23. Binding Behavior of Subphthalocyanine-Tagged Testosterone with Human Serum Albumin at the n-Hexane/Water Interface. Adachi, K., Watarai, H. Anal. Chem. (2006) [Pubmed]
  24. Selective inhibition by chloramphenicol of cytochrome P-450 isozymes in rat lung and liver involved in the hydroxylation of n-hexane. Näslund, B.M., Halpert, J. J. Pharmacol. Exp. Ther. (1984) [Pubmed]
  25. Determination of triclosan as its pentafluorobenzoyl ester in human plasma and milk using electron capture negative ionization mass spectrometry. Allmyr, M., McLachlan, M.S., Sandborgh-Englund, G., Adolfsson-Erici, M. Anal. Chem. (2006) [Pubmed]
  26. Spongiform immobilization architecture of ionotropy polymer hydrogel coentrapping alcohol oxidase and horseradish peroxidase with octadecylsilica for optical biosensing alcohol in organic solvent. Wu, X.J., Choi, M.M. Anal. Chem. (2004) [Pubmed]
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  28. Induction of cytochrome P450 isozymes by simultaneous inhalation exposure of hens to n-hexane and methyl iso-butyl ketone (MiBK). Lapadula, D.M., Habig, C., Gupta, R.P., Abou-Donia, M.B. Biochem. Pharmacol. (1991) [Pubmed]
  29. Involvement of outer membrane protein TolC, a possible member of the mar-sox regulon, in maintenance and improvement of organic solvent tolerance of Escherichia coli K-12. Aono, R., Tsukagoshi, N., Yamamoto, M. J. Bacteriol. (1998) [Pubmed]
  30. Oxidative mechanisms in nigral cell death in Parkinson's disease. Jenner, P. Mov. Disord. (1998) [Pubmed]
  31. Cholinesterases in blood plasma and tissues of rats treated with n-hexane or with its neurotoxic metabolite 2,5-hexanedione. Bastone, A., Frontali, N., Mallozzi, C., Sbraccia, M., Settimi, L. Arch. Toxicol. (1987) [Pubmed]
  32. Cloning of organic solvent tolerance gene ostA that determines n-hexane tolerance level in Escherichia coli. Aono, R., Negishi, T., Nakajima, H. Appl. Environ. Microbiol. (1994) [Pubmed]
  33. Anti-inflammatory active polyacetylenes from Bidens campylotheca. Redl, K., Breu, W., Davis, B., Bauer, R. Planta Med. (1994) [Pubmed]
  34. Synthesis and evaluation of pharmacological and pharmacokinetic properties of monopropyl analogs of 5-, 7-, and 8-[[(trifluoromethyl)sulfonyl]oxy]-2-aminotetralins: central dopamine and serotonin receptor activity. Sonesson, C., Barf, T., Nilsson, J., Dijkstra, D., Carlsson, A., Svensson, K., Smith, M.W., Martin, I.J., Duncan, J.N., King, L.J. J. Med. Chem. (1995) [Pubmed]
  35. Use of various clean-up procedures for the analysis of ochratoxin A in cereals. Solfrizzo, M., Avantaggiato, G., Visconti, A. Journal of chromatography. A. (1998) [Pubmed]
  36. Determination of the anti-ischaemic drug bepridil in human plasma using gas chromatography with nitrogen-sensitive detection. Vink, J., van Hal, J.H., Pognat, J.F., Bouquet des Chaut, J.L. J. Chromatogr. (1983) [Pubmed]
  37. Enantioseparation of novel chiral heterometal tetrahedral clusters by high-performance liquid chromatography. Zhu, X., Cai, Y., Zhang, W., Chen, L., Li, Y. Journal of chromatography. A. (2003) [Pubmed]
  38. Total antioxidant capacity assay of human serum using copper(II)-neocuproine as chromogenic oxidant: the CUPRAC method. Apak, R., Güçlü, K., Ozyürek, M., Karademir, S.E., Altun, M. Free Radic. Res. (2005) [Pubmed]
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