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Gene Review

Nhcp1  -  nonhistone chromosomal protein 1

Mus musculus

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Disease relevance of Nhcp1


High impact information on Nhcp1


Biological context of Nhcp1


Anatomical context of Nhcp1

  • Comparison of the two-dimensional gel electrophoretograms of the nonhistone chromosomal proteins of mouse and human cell lines showed 400 and 280 chromosomal proteins, respectively, of which about 75% were electrophoretically identical [1].

Associations of Nhcp1 with chemical compounds


Physical interactions of Nhcp1


Other interactions of Nhcp1


Analytical, diagnostic and therapeutic context of Nhcp1


  1. Expression of human and mouse nonhistone chromosomal proteins in hybrid mouse erythroleukemia cells containing a single human chromosome. Bode, U., Deisseroth, A., Hendrick, D. Proc. Natl. Acad. Sci. U.S.A. (1981) [Pubmed]
  2. Gene expression in mouse neuroblastoma cells: properties of the genome. Zornetzer, M.S., Stein, G.S. Proc. Natl. Acad. Sci. U.S.A. (1975) [Pubmed]
  3. Metabolic stability of nonhistone chromosomal proteins in Ehrlich ascites tumour cells. Srebreva, L., Russev, G., Tsanev, R. Int. J. Biochem. (1979) [Pubmed]
  4. Monoclonal antibodies specific for tight-binding human chromatin antigens reveal structural rearrangements within the nucleus during the cell cycle. Bhorjee, J.S., Barclay, S.L., Wedrychowski, A., Smith, A.M. J. Cell Biol. (1983) [Pubmed]
  5. Monoclonal antibodies against a specific nonhistone chromosomal protein of Drosophila associated with active genes. Howard, G.C., Abmayr, S.M., Shinefeld, L.A., Sato, V.L., Elgin, S.C. J. Cell Biol. (1981) [Pubmed]
  6. Critical role of the HMGI(Y) proteins in adipocytic cell growth and differentiation. Melillo, R.M., Pierantoni, G.M., Scala, S., Battista, S., Fedele, M., Stella, A., De Biasio, M.C., Chiappetta, G., Fidanza, V., Condorelli, G., Santoro, M., Croce, C.M., Viglietto, G., Fusco, A. Mol. Cell. Biol. (2001) [Pubmed]
  7. HMG1-related DNA-binding protein isolated with V-(D)-J recombination signal probes. Shirakata, M., Hüppi, K., Usuda, S., Okazaki, K., Yoshida, K., Sakano, H. Mol. Cell. Biol. (1991) [Pubmed]
  8. Elevated high mobility group-I(Y) gene expression is associated with progressive transformation of mouse mammary epithelial cells. Ram, T.G., Reeves, R., Hosick, H.L. Cancer Res. (1993) [Pubmed]
  9. Nucleotide sequence of a mouse cDNA encoding the nonhistone chromosomal high mobility group protein-1 (HMG1). Yotov, W.V., St-Arnaud, R. Nucleic Acids Res. (1992) [Pubmed]
  10. Tumor promoter induces high mobility group HMG-Y protein expression in transformation-sensitive but not -resistant cells. Cmarik, J.L., Li, Y., Ogram, S.A., Min, H., Reeves, R., Colburn, N.H. Oncogene (1998) [Pubmed]
  11. Inhibition of the phosphorylation of nonhistone chromosomal proteins by cordycepin and xylosyladenine in L1210 cells in vitro. Legraverend, M., Glazer, R.I. Mol. Pharmacol. (1978) [Pubmed]
  12. New androgen-stimulated proteins in the kidneys of female mice. Mills, N.C., Bardin, C.W. Endocrinology (1980) [Pubmed]
  13. Chromatin fractionation procedure that yields nucleosomes containing near-stoichiometric amounts of high mobility group nonhistone chromosomal proteins. Jackson, J.B., Pollock, J.M., Rill, R.L. Biochemistry (1979) [Pubmed]
  14. Fractionation of nonhistone chromosomal proteins utilizing hydroxyapatite chromatography. MacGillivray, A.J. Methods Cell Biol. (1977) [Pubmed]
  15. Identification of nonhistone chromosomal proteins binding specifically to cloned alpha-fetoprotein DNA sequences. Lesser, B.H., Chan, H.W., Stockton, J.F. Can. J. Biochem. Cell Biol. (1983) [Pubmed]
  16. Identification and genetic mapping of the murine gene and 20 related sequences encoding chromosomal protein HMG-17. Johnson, K.R., Cook, S.A., Ward-Bailey, P., Bustin, M., Davisson, M.T. Mamm. Genome (1993) [Pubmed]
  17. Nuclear estrogen receptor and nonhistone chromosomal proteins in hormonal independency of murine breast cancers. Kiang, D.T., Handschin, B., Zhang, H.J. Cancer Res. (1984) [Pubmed]
  18. Genetic analysis of nonhistone chromosomal protein inheritance in recombinant inbred mouse strains using two-dimensional electrophoresis. Ramagli, L.S., Womack, J.E., Rodriguez, L.V. Biochem. Genet. (1990) [Pubmed]
  19. Induction of early transcription in one-cell mouse embryos by microinjection of the nonhistone chromosomal protein HMG-I. Beaujean, N., Bouniol-Baly, C., Monod, C., Kissa, K., Jullien, D., Aulner, N., Amirand, C., Debey, P., Käs, E. Dev. Biol. (2000) [Pubmed]
  20. Assembly of DNA with histones and nonhistone chromosomal proteins in vitro. Bekhor, I., Feldman, B. Biochemistry (1976) [Pubmed]
  21. Fractionation of nonhistone chromosomal proteins utilizing isoelectric focusing techniques. MacGillivray, A.J. Methods Cell Biol. (1977) [Pubmed]
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