Gene Review:
Ptprn2 - protein tyrosine phosphatase, receptor...
Rattus norvegicus
Synonyms:
PTP NE-6, PTPNE6, Phogrin, R-PTP-N2, Receptor-type tyrosine-protein phosphatase N2
- Molecular cloning of phogrin, a protein-tyrosine phosphatase homologue localized to insulin secretory granule membranes. Wasmeier, C., Hutton, J.C. J. Biol. Chem. (1996)
- Identification of the 37-kDa antigen in IDDM as a tyrosine phosphatase-like protein (phogrin) related to IA-2. Hawkes, C.J., Wasmeier, C., Christie, M.R., Hutton, J.C. Diabetes (1996)
- Secretory granules are recaptured largely intact after stimulated exocytosis in cultured endocrine cells. Taraska, J.W., Perrais, D., Ohara-Imaizumi, M., Nagamatsu, S., Almers, W. Proc. Natl. Acad. Sci. U.S.A. (2003)
- Different regulated expression of the tyrosine phosphatase-like proteins IA-2 and phogrin by glucose and insulin in pancreatic islets: relationship to development of insulin secretory responses in early life. Löbner, K., Steinbrenner, H., Roberts, G.A., Ling, Z., Huang, G.C., Piquer, S., Pipeleers, D.G., Seissler, J., Christie, M.R. Diabetes (2002)
- Secretory-granule dynamics visualized in vivo with a phogrin-green fluorescent protein chimaera. Pouli, A.E., Emmanouilidou, E., Zhao, C., Wasmeier, C., Hutton, J.C., Rutter, G.A. Biochem. J. (1998)
- PTP NE-6: a brain-enriched receptor-type protein tyrosine phosphatase with a divergent catalytic domain. Fitzgerald, L.R., Walton, K.M., Dixon, J.E., Largent, B.L. J. Neurochem. (1997)
- IDA-1, a Caenorhabditis elegans homolog of the diabetic autoantigens IA-2 and phogrin, is expressed in peptidergic neurons in the worm. Zahn, T.R., Macmorris, M.A., Dong, W., Day, R., Hutton, J.C. J. Comp. Neurol. (2001)
- Autoantibodies to protein tyrosine phosphatase-like proteins in type I diabetes. Overlapping specificities to phogrin and ICA512/IA-2. Kawasaki, E., Eisenbarth, G.S., Wasmeier, C., Hutton, J.C. Diabetes (1996)