Gene Review:
HOXD1 - homeobox D1
Homo sapiens
Synonyms:
HOX4, HOX4G, Homeobox protein Hox-D1, Homeobox protein Hox-GG, Hox-4.7
- Expression of murine HOXD9 during embryonic joint patterning and in human T lymphotropic virus type I tax transgenic mice with arthropathy resembling rheumatoid arthritis. Khoa, N.D., Hasunuma, T., Kobata, T., Kato, T., Nishioka, K. Arthritis Rheum. (1999)
- HOX gene clusters are hotspots of de novo methylation in CpG islands of human lung adenocarcinomas. Shiraishi, M., Sekiguchi, A., Oates, A.J., Terry, M.J., Miyamoto, Y. Oncogene (2002)
- Testing for genetic associations in a spina bifida population: analysis of the HOX gene family and human candidate gene regions implicated by mouse models of neural tube defects. Volcik, K.A., Blanton, S.H., Kruzel, M.C., Townsend, I.T., Tyerman, G.H., Mier, R.J., Northrup, H. Am. J. Med. Genet. (2002)
- Chromatin looping and the probability of transcription. Li, Q., Barkess, G., Qian, H. Trends Genet. (2006)
- Missense mutations in the homeodomain of HOXD13 are associated with brachydactyly types D and E. Johnson, D., Kan, S.H., Oldridge, M., Trembath, R.C., Roche, P., Esnouf, R.M., Giele, H., Wilkie, A.O. Am. J. Hum. Genet. (2003)
- A 117-kb microdeletion removing HOXD9-HOXD13 and EVX2 causes synpolydactyly. Goodman, F.R., Majewski, F., Collins, A.L., Scambler, P.J. Am. J. Hum. Genet. (2002)
- Monodactylous limbs and abnormal genitalia are associated with hemizygosity for the human 2q31 region that includes the HOXD cluster. Del Campo, M., Jones, M.C., Veraksa, A.N., Curry, C.J., Jones, K.L., Mascarello, J.T., Ali-Kahn-Catts, Z., Drumheller, T., McGinnis, W. Am. J. Hum. Genet. (1999)
- Cloning of HOXD1 from unfertilised human oocytes and expression analyses during murine oogenesis and embryogenesis. Pitera, J.E., Milla, P.J., Scambler, P., Adjaye, J. Mech. Dev. (2001)
- An I47L substitution in the HOXD13 homeodomain causes a novel human limb malformation by producing a selective loss of function. Caronia, G., Goodman, F.R., McKeown, C.M., Scambler, P.J., Zappavigna, V. Development (2003)
- The HOXD11 gene is fused to the NUP98 gene in acute myeloid leukemia with t(2;11)(q31;p15). Taketani, T., Taki, T., Shibuya, N., Ito, E., Kitazawa, J., Terui, K., Hayashi, Y. Cancer Res. (2002)
- Order of six loci at 2q24-q31 and orientation of the HOXD locus. Rossi, E., Faiella, A., Zeviani, M., Labeit, S., Floridia, G., Brunelli, S., Cammarata, M., Boncinelli, E., Zuffardi, O. Genomics (1994)
- Cooperating morphogens control hoxd gene expression in the developing vertebrate limb. Papageorgiou, S. J. Theor. Biol. (1998)
- Recombinant limbs as a model to study homeobox gene regulation during limb development. Ros, M.A., Lyons, G.E., Mackem, S., Fallon, J.F. Dev. Biol. (1994)
- HOXC and HOXD gene expression in human endometrium: lack of redundancy with HOXA paralogs. Akbas, G.E., Taylor, H.S. Biol. Reprod. (2004)
- The mouse Hoxd13(spdh) mutation, a polyalanine expansion similar to human type II synpolydactyly (SPD), disrupts the function but not the expression of other Hoxd genes. Bruneau, S., Johnson, K.R., Yamamoto, M., Kuroiwa, A., Duboule, D. Dev. Biol. (2001)
- An acceptor splice site mutation in HOXD13 results in variable hand, but consistent foot malformations. Kan, S.H., Johnson, D., Giele, H., Wilkie, A.O. Am. J. Med. Genet. A (2003)
- Isolation and characterization of the human homeobox gene HOX D1. Appukuttan, B., Sood, R., Ott, S., Makalowska, I., Patel, R.J., Wang, X., Robbins, C.M., Brownstein, M.J., Stout, J.T. Mol. Biol. Rep. (2000)