Gene Review:
CYP3A12 - cytochrome P-450 3A12
Canis lupus familiaris
- Escherichia coli expression and substrate specificities of canine cytochrome P450 3A12 and rabbit cytochrome P450 3A6. Born, S.L., Fraser, D.J., Harlow, G.R., Halpert, J.R. J. Pharmacol. Exp. Ther. (1996)
- Selective inhibition of dog hepatic CYP2B11 and CYP3A12. Lu, P., Singh, S.B., Carr, B.A., Fang, Y., Xiang, C.D., Rushmore, T.H., Rodrigues, A.D., Shou, M. J. Pharmacol. Exp. Ther. (2005)
- Isolation, heterologous expression and functional characterization of a novel cytochrome P450 3A enzyme from a canine liver cDNA library. Fraser, D.J., Feyereisen, R., Harlow, G.R., Halpert, J.R. J. Pharmacol. Exp. Ther. (1997)
- Substrate specificity and kinetic properties of seven heterologously expressed dog cytochromes p450. Shou, M., Norcross, R., Sandig, G., Lu, P., Li, Y., Lin, Y., Mei, Q., Rodrigues, A.D., Rushmore, T.H. Drug Metab. Dispos. (2003)
- In vitro characterization of the inhibitory effects of ketoconazole on metabolic activities of cytochrome P-450 in canine hepatic microsomes. Kuroha, M., Kuze, Y., Shimoda, M., Kokue, E. Am. J. Vet. Res. (2002)
- mRNA and protein expression of dog liver cytochromes P450 in relation to the metabolism of human CYP2C substrates. Graham, M.J., Bell, A.R., Crewe, H.K., Moorcraft, C.L., Walker, L., Whittaker, E.F., Lennard, M.S. Xenobiotica (2003)
- Nuclear receptor and target gene mRNA abundance in duodenum and colon of dogs with chronic enteropathies. Greger, D.L., Gropp, F., Morel, C., Sauter, S., Blum, J.W. Domest. Anim. Endocrinol. (2006)
- The effect of bergamottin on diazepam plasma levels and P450 enzymes in beagle dogs. Sahi, J., Reyner, E.L., Bauman, J.N., Gueneva-Boucheva, K., Burleigh, J.E., Thomas, V.H. Drug Metab. Dispos. (2002)
- Characterization of the effects of tebufelone on hepatic cytochromes P450 in the beagle dog. Smith, B.J., Zupan, L.A., Hu, J.K., Diters, R.W., Gibson, G.W., Norton, J.N. Drug Metab. Dispos. (1996)
- Induction of intestinal cytochrome P450 (CYP3A) by rifampicin in beagle dogs. Kyokawa, Y., Nishibe, Y., Wakabayashi, M., Harauchi, T., Maruyama, T., Baba, T., Ohno, K. Chem. Biol. Interact. (2001)
- Comparative analysis of in vitro and in vivo pharmacokinetic parameters related to individual variability of GTS-21 in canine. Azuma, R., Komuro, M., Kawaguchi, Y., Okudaira, K., Hayashi, M., Kiwada, H. Drug Metab. Pharmacokinet. (2002)