Gene Review:
MIOX - myo-inositol oxygenase
Homo sapiens
Synonyms:
ALDRL6, Aldehyde reductase-like 6, Inositol oxygenase, KSP32, Kidney-specific protein 32, ...
- Expression of myo-inositol oxygenase in tissues susceptible to diabetic complications. Arner, R.J., Prabhu, K.S., Krishnan, V., Johnson, M.C., Reddy, C.C. Biochem. Biophys. Res. Commun. (2006)
- Gene regulation of aldose-, aldehyde- and a renal specific oxido reductase (RSOR) in the pathobiology of diabetes mellitus. Danesh, F.R., Wada, J., Wallner, E.I., Sahai, A., Srivastava, S.K., Kanwar, Y.S. Current medicinal chemistry. (2003)
- Identification of a novel kidney-specific gene downregulated in acute ischemic renal failure. Hu, E., Chen, Z., Fredrickson, T., Gellai, M., Jugus, M., Contino, L., Spurr, N., Sims, M., Halsey, W., Van Horn, S., Mao, J., Sathe, G., Brooks, D. Am. J. Physiol. Renal Physiol. (2000)
- Evidence for C-H cleavage by an iron-superoxide complex in the glycol cleavage reaction catalyzed by myo-inositol oxygenase. Xing, G., Diao, Y., Hoffart, L.M., Barr, E.W., Prabhu, K.S., Arner, R.J., Reddy, C.C., Krebs, C., Bollinger, J.M. Proc. Natl. Acad. Sci. U.S.A. (2006)
- Crystal structure of a substrate complex of myo-inositol oxygenase, a di-iron oxygenase with a key role in inositol metabolism. Brown, P.M., Caradoc-Davies, T.T., Dickson, J.M., Cooper, G.J., Loomes, K.M., Baker, E.N. Proc. Natl. Acad. Sci. U.S.A. (2006)
- Up-regulation of human myo-inositol oxygenase by hyperosmotic stress in renal proximal tubular epithelial cells. Prabhu, K.S., Arner, R.J., Vunta, H., Reddy, C.C. J. Biol. Chem. (2005)
- A Coupled Dinuclear Iron Cluster that Is Perturbed by Substrate Binding in myo-Inositol Oxygenase. Xing, G., Hoffart, L.M., Diao, Y., Prabhu, K.S., Arner, R.J., Reddy, C.C., Krebs, C., Bollinger, J.M. Biochemistry (2006)
- Oxygen Activation by a Mixed-Valent, Diiron(II/III) Cluster in the Glycol Cleavage Reaction Catalyzed by myo-Inositol Oxygenase. Xing, G., Barr, E.W., Diao, Y., Hoffart, L.M., Prabhu, K.S., Arner, R.J., Reddy, C.C., Krebs, C., Bollinger, J.M. Biochemistry (2006)
- Concerning the mechanism for transfer of D-glucuronate from myo-inositol oxygenase to D-glucuronate reductase. Naber, N.I., Hamilton, G.A. Biochim. Biophys. Acta (1987)