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SLC25A1  -  solute carrier family 25 (mitochondrial...

Homo sapiens

Synonyms: CTP, Citrate transport protein, D2L2AD, SEA, SLC20A3, ...
 
 
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Disease relevance of SLC25A1

 

High impact information on SLC25A1

 

Biological context of SLC25A1

 

Anatomical context of SLC25A1

 

Associations of SLC25A1 with chemical compounds

  • In primary cultures of neurons, uptake of citrate was also Na+ dependent and saturable with a Kt value of 16.2 microM, which was different from that observed in astrocytes, suggesting that different Na+-dependent citrate transport systems are expressed in neurons and astrocytes [5].
  • The mitochondrial citrate transport protein: Evidence for a steric interaction between glutamine 182 and leucine 120 and its relationship to the substrate translocation pathway and identification of other mechanistically essential residues [12].
 

Other interactions of SLC25A1

References

  1. Expression of Na+-dependent citrate transport in a strongly metastatic human prostate cancer PC-3M cell line: regulation by voltage-gated Na+ channel activity. Mycielska, M.E., Palmer, C.P., Brackenbury, W.J., Djamgoz, M.B. J. Physiol. (Lond.) (2005) [Pubmed]
  2. The human mitochondrial citrate transporter gene (SLC20A3) maps to chromosome band 22q11 within a region implicated in DiGeorge syndrome, velo-cardio-facial syndrome and schizophrenia. Stoffel, M., Karayiorgou, M., Espinosa, R., Beau, M.M. Hum. Genet. (1996) [Pubmed]
  3. Identification of dicarboxylate carrier Slc25a10 as malate transporter in de novo fatty acid synthesis. Mizuarai, S., Miki, S., Araki, H., Takahashi, K., Kotani, H. J. Biol. Chem. (2005) [Pubmed]
  4. The tonoplast-associated citrate binding protein (CBP) of Hevea brasiliensis. Photoaffinity labeling, purification, and cloning of the corresponding gene. Rentsch, D., Görlach, J., Vogt, E., Amrhein, N., Martinoia, E. J. Biol. Chem. (1995) [Pubmed]
  5. Functional and molecular identification of sodium-coupled dicarboxylate transporters in rat primary cultured cerebrocortical astrocytes and neurons. Yodoya, E., Wada, M., Shimada, A., Katsukawa, H., Okada, N., Yamamoto, A., Ganapathy, V., Fujita, T. J. Neurochem. (2006) [Pubmed]
  6. Cloning, genomic organization, and chromosomal localization of human citrate transport protein to the DiGeorge/velocardiofacial syndrome minimal critical region. Goldmuntz, E., Wang, Z., Roe, B.A., Budarf, M.L. Genomics (1996) [Pubmed]
  7. Expression of the renal Na+/dicarboxylate cotransporter, NaDC-1, in COS-7 cells. Pajor, A.M., Valmonte, H.G. Pflugers Arch. (1996) [Pubmed]
  8. Citrate transport in the human prostate epithelial PNT2-C2 cell line: electrophysiological analyses. Mycielska, M.E., Djamgoz, M.B. J. Physiol. (Lond.) (2004) [Pubmed]
  9. Characterization of citrate transport through the plasma membrane in a carrot mutant cell line with enhanced citrate excretion. Ohno, T., Koyama, H., Hara, T. Plant Cell Physiol. (2003) [Pubmed]
  10. Citrate transport in liposomes reconstituted with triton extracts from mitochondria. Stipani, I., Krämer, R., Palmieri, F., Klingenberg, M. Biochem. Biophys. Res. Commun. (1980) [Pubmed]
  11. The effect of agaric acid on citrate transport in rat liver mitochondria. Chávez, E., Chávez, R., Carrasco, N. Life Sci. (1978) [Pubmed]
  12. The mitochondrial citrate transport protein: Evidence for a steric interaction between glutamine 182 and leucine 120 and its relationship to the substrate translocation pathway and identification of other mechanistically essential residues. Ma, C., Remani, S., Kotaria, R., Mayor, J.A., Walters, D.E., Kaplan, R.S. Biochim. Biophys. Acta (2006) [Pubmed]
 
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