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Gene Review

PER1  -  1-Cys peroxiredoxin PER1

Arabidopsis thaliana

Synonyms: 1-CYS PEROXIREDOXIN, 1-cysteine peroxiredoxin 1, ATPER1, F21D18.15, F21D18_15
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Disease relevance of ATPER1


High impact information on ATPER1


Biological context of ATPER1


Anatomical context of ATPER1

  • This study addressed the chloroplast peroxiredoxin Prx Q and showed that its subcellular location is the lumen of the thylakoid membrane [7].

Associations of ATPER1 with chemical compounds

  • Antisense suppression of 2-cysteine peroxiredoxin in Arabidopsis specifically enhances the activities and expression of enzymes associated with ascorbate metabolism but not glutathione metabolism [8].
  • However, seeds from lines overexpressing PER1 were less inclined to germinate than wild-type seeds in the presence of NaCl, mannitol, and methyl viologen, suggesting that Prx can sense harsh environmental surroundings and play a part in the inhibition of germination under unfavorable conditions [1].

Other interactions of ATPER1


Analytical, diagnostic and therapeutic context of ATPER1


  1. Seed 1-cysteine peroxiredoxin antioxidants are not involved in dormancy, but contribute to inhibition of germination during stress. Haslekås, C., Viken, M.K., Grini, P.E., Nygaard, V., Nordgard, S.H., Meza, T.J., Aalen, R.B. Plant Physiol. (2003) [Pubmed]
  2. The plastidic 2-cysteine peroxiredoxin is a target for a thioredoxin involved in the protection of the photosynthetic apparatus against oxidative damage. Broin, M., Cuiné, S., Eymery, F., Rey, P. Plant Cell (2002) [Pubmed]
  3. Peroxiredoxin Q of Arabidopsis thaliana is attached to the thylakoids and functions in context of photosynthesis. Lamkemeyer, P., Laxa, M., Collin, V., Li, W., Finkemeier, I., Schöttler, M.A., Holtkamp, V., Tognetti, V.B., Issakidis-Bourguet, E., Kandlbinder, A., Weis, E., Miginiac-Maslow, M., Dietz, K.J. Plant J. (2006) [Pubmed]
  4. Ascorbate-deficient mutants of Arabidopsis grow in high light despite chronic photooxidative stress. Müller-Moulé, P., Golan, T., Niyogi, K.K. Plant Physiol. (2004) [Pubmed]
  5. ABI3 mediates expression of the peroxiredoxin antioxidant AtPER1 gene and induction by oxidative stress. Haslekås, C., Grini, P.E., Nordgard, S.H., Thorstensen, T., Viken, M.K., Nygaard, V., Aalen, R.B. Plant Mol. Biol. (2003) [Pubmed]
  6. A peroxiredoxin Q homolog from gentians is involved in both resistance against fungal disease and oxidative stress. Kiba, A., Nishihara, M., Tsukatani, N., Nakatsuka, T., Kato, Y., Yamamura, S. Plant Cell Physiol. (2005) [Pubmed]
  7. The Prx Q protein of Arabidopsis thaliana is a member of the luminal chloroplast proteome. Petersson, U.A., Kieselbach, T., Garc??a-Cerd??n, J.G., Schr??der, W.P. FEBS Lett. (2006) [Pubmed]
  8. Antisense suppression of 2-cysteine peroxiredoxin in Arabidopsis specifically enhances the activities and expression of enzymes associated with ascorbate metabolism but not glutathione metabolism. Baier, M., Noctor, G., Foyer, C.H., Dietz, K.J. Plant Physiol. (2000) [Pubmed]
  9. Effects of leaf ascorbate content on defense and photosynthesis gene expression in Arabidopsis thaliana. Kiddle, G., Pastori, G.M., Bernard, S., Pignocchi, C., Antoniw, J., Verrier, P.J., Foyer, C.H. Antioxid. Redox Signal. (2003) [Pubmed]
  10. Molecular cloning and characterization of peroxiredoxin from Toxoplasma gondii. Son, E.S., Song, K.J., Shin, J.C., Nam, H.W. Korean J. Parasitol. (2001) [Pubmed]
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