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Gene Review

Fgfr3  -  fibroblast growth factor receptor 3

Rattus norvegicus

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Disease relevance of Fgfr3


High impact information on Fgfr3


Biological context of Fgfr3


Anatomical context of Fgfr3


Associations of Fgfr3 with chemical compounds


Analytical, diagnostic and therapeutic context of Fgfr3


  1. Skeletal dysplasia and defective chondrocyte differentiation by targeted overexpression of fibroblast growth factor 9 in transgenic mice. Garofalo, S., Kliger-Spatz, M., Cooke, J.L., Wolstin, O., Lunstrum, G.P., Moshkovitz, S.M., Horton, W.A., Yayon, A. J. Bone Miner. Res. (1999) [Pubmed]
  2. Fibroblast growth factor receptor-3 as a marker for precartilaginous stem cells. Robinson, D., Hasharoni, A., Cohen, N., Yayon, A., Moskowitz, R.M., Nevo, Z. Clin. Orthop. Relat. Res. (1999) [Pubmed]
  3. Sustained ERK1/2 but not STAT1 or 3 activation is required for thanatophoric dysplasia phenotypes in PC12 cells. Nowroozi, N., Raffioni, S., Wang, T., Apostol, B.L., Bradshaw, R.A., Thompson, L.M. Hum. Mol. Genet. (2005) [Pubmed]
  4. Fgfr3 expression by astrocytes and their precursors: evidence that astrocytes and oligodendrocytes originate in distinct neuroepithelial domains. Pringle, N.P., Yu, W.P., Howell, M., Colvin, J.S., Ornitz, D.M., Richardson, W.D. Development (2003) [Pubmed]
  5. The kinase activity of fibroblast growth factor receptor 3 with activation loop mutations affects receptor trafficking and signaling. Lievens, P.M., Mutinelli, C., Baynes, D., Liboi, E. J. Biol. Chem. (2004) [Pubmed]
  6. Signal transduction pathway of human fibroblast growth factor receptor 3. Identification of a novel 66-kDa phosphoprotein. Kanai, M., Göke, M., Tsunekawa, S., Podolsky, D.K. J. Biol. Chem. (1997) [Pubmed]
  7. Effect of transmembrane and kinase domain mutations on fibroblast growth factor receptor 3 chimera signaling in PC12 cells. A model for the control of receptor tyrosine kinase activation. Raffioni, S., Zhu, Y.Z., Bradshaw, R.A., Thompson, L.M. J. Biol. Chem. (1998) [Pubmed]
  8. Expression of the fibroblast growth factor receptor genes in fracture repair. Rundle, C.H., Miyakoshi, N., Ramirez, E., Wergedal, J.E., Lau, K.H., Baylink, D.J. Clin. Orthop. Relat. Res. (2002) [Pubmed]
  9. Differential activation of cysteine-substitution mutants of fibroblast growth factor receptor 3 is determined by cysteine localization. Adar, R., Monsonego-Ornan, E., David, P., Yayon, A. J. Bone Miner. Res. (2002) [Pubmed]
  10. Molecular cloning and developmental expression of rat fibroblast growth factor receptor 3. Claus, P., Grothe, C. Histochem. Cell Biol. (2001) [Pubmed]
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