Gene Review:
htl - heartless
Drosophila melanogaster
Synonyms:
CG7223, CT22273, CT39172, DFGF-R1, DFGF-R2, ...
- Sprouty, an intracellular inhibitor of Ras signaling. Casci, T., Vinós, J., Freeman, M. Cell (1999)
- pyramus and thisbe: FGF genes that pattern the mesoderm of Drosophila embryos. Stathopoulos, A., Tam, B., Ronshaugen, M., Frasch, M., Levine, M. Genes Dev. (2004)
- Drosophila awd, the homolog of human nm23, regulates FGF receptor levels and functions synergistically with shi/dynamin during tracheal development. Dammai, V., Adryan, B., Lavenburg, K.R., Hsu, T. Genes Dev. (2003)
- Combinatorial signaling codes for the progressive determination of cell fates in the Drosophila embryonic mesoderm. Carmena, A., Gisselbrecht, S., Harrison, J., Jiménez, F., Michelson, A.M. Genes Dev. (1998)
- FGF8-like1 and FGF8-like2 encode putative ligands of the FGF receptor Htl and are required for mesoderm migration in the Drosophila gastrula. Gryzik, T., Müller, H.A. Curr. Biol. (2004)
- Specificity of FGF signaling in cell migration in Drosophila. Dossenbach, C., Röck, S., Affolter, M. Development (2001)
- p120 Ras GTPase-activating protein associates with fibroblast growth factor receptors in Drosophila. Woodcock, S.A., Hughes, D.A. Biochem. J. (2004)
- Elucidation of the role of breathless, a Drosophila FGF receptor homolog, in tracheal cell migration. Reichman-Fried, M., Dickson, B., Hafen, E., Shilo, B.Z. Genes Dev. (1994)
- The RhoGEF Pebble is required for cell shape changes during cell migration triggered by the Drosophila FGF receptor Heartless. Schumacher, S., Gryzik, T., Tannebaum, S., Müller, H.A. Development (2004)
- Two FGF-receptor homologues of Drosophila: one is expressed in mesodermal primordium in early embryos. Shishido, E., Higashijima, S., Emori, Y., Saigo, K. Development (1993)
- Neuroglian and FasciclinII can promote neurite outgrowth via the FGF receptor Heartless. Forni, J.J., Romani, S., Doherty, P., Tear, G. Mol. Cell. Neurosci. (2004)
- Heartless, a Drosophila FGF receptor homolog, is essential for cell migration and establishment of several mesodermal lineages. Beiman, M., Shilo, B.Z., Volk, T. Genes Dev. (1996)
- Heparan sulfate proteoglycans are essential for FGF receptor signaling during Drosophila embryonic development. Lin, X., Buff, E.M., Perrimon, N., Michelson, A.M. Development (1999)
- Dynamic transcriptional regulatory complexes, including E2F4, p107, p130, and Sp1, control fibroblast growth factor receptor 1 gene expression during myogenesis. Parakati, R., DiMario, J.X. J. Biol. Chem. (2005)
- heartless encodes a fibroblast growth factor receptor (DFR1/DFGF-R2) involved in the directional migration of early mesodermal cells in the Drosophila embryo. Gisselbrecht, S., Skeath, J.B., Doe, C.Q., Michelson, A.M. Genes Dev. (1996)
- Sprouty is a general inhibitor of receptor tyrosine kinase signaling. Reich, A., Sapir, A., Shilo, B. Development (1999)
- D-mef2: a Drosophila mesoderm-specific MADS box-containing gene with a biphasic expression profile during embryogenesis. Nguyen, H.T., Bodmer, R., Abmayr, S.M., McDermott, J.C., Spoerel, N.A. Proc. Natl. Acad. Sci. U.S.A. (1994)
- Hindgut visceral mesoderm requires an ectodermal template for normal development in Drosophila. San Martin , B., Bate, M. Development (2001)
- Repression of fibroblast growth factor receptor 1 gene expression by E2F4 in skeletal muscle cells. Parakati, R., Dimario, J.X. Dev. Dyn. (2005)