Gene Review:
ADA2 - Ada2p
Saccharomyces cerevisiae S288c
Synonyms:
D9461.33, Transcriptional adapter 2, YDR448W
- Functional similarity and physical association between GCN5 and ADA2: putative transcriptional adaptors. Marcus, G.A., Silverman, N., Berger, S.L., Horiuchi, J., Guarente, L. EMBO J. (1994)
- Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: characterization of an Ada complex and the SAGA (Spt/Ada) complex. Grant, P.A., Duggan, L., Côté, J., Roberts, S.M., Brownell, J.E., Candau, R., Ohba, R., Owen-Hughes, T., Allis, C.D., Winston, F., Berger, S.L., Workman, J.L. Genes Dev. (1997)
- Yeast ADA2 protein binds to the VP16 protein activation domain and activates transcription. Silverman, N., Agapite, J., Guarente, L. Proc. Natl. Acad. Sci. U.S.A. (1994)
- The E2 ubiquitin conjugase Rad6 is required for the ArgR/Mcm1 repression of ARG1 transcription. Turner, S.D., Ricci, A.R., Petropoulos, H., Genereaux, J., Skerjanc, I.S., Brandl, C.J. Mol. Cell. Biol. (2002)
- Tra1p is a component of the yeast Ada.Spt transcriptional regulatory complexes. Saleh, A., Schieltz, D., Ting, N., McMahon, S.B., Litchfield, D.W., Yates, J.R., Lees-Miller, S.P., Cole, M.D., Brandl, C.J. J. Biol. Chem. (1998)
- Role for ADA/GCN5 products in antagonizing chromatin-mediated transcriptional repression. Pollard, K.J., Peterson, C.L. Mol. Cell. Biol. (1997)
- ADR1 activation domains contact the histone acetyltransferase GCN5 and the core transcriptional factor TFIIB. Chiang, Y.C., Komarnitsky, P., Chase, D., Denis, C.L. J. Biol. Chem. (1996)
- Regulation of gene expression by glucose in Saccharomyces cerevisiae: a role for ADA2 and ADA3/NGG1. Wu, M., Newcomb, L., Heideman, W. J. Bacteriol. (1999)
- PfADA2, a Plasmodium falciparum homologue of the transcriptional coactivator ADA2 and its in vivo association with the histone acetyltransferase PfGCN5. Fan, Q., An, L., Cui, L. Gene (2004)
- The Drosophila histone acetyltransferase gcn5 and transcriptional adaptor ada2a are involved in nucleosomal histone h4 acetylation. Ciurciu, A., Komonyi, O., Pankotai, T., Boros, I.M. Mol. Cell. Biol. (2006)
- ADA3, a putative transcriptional adaptor, consists of two separable domains and interacts with ADA2 and GCN5 in a trimeric complex. Horiuchi, J., Silverman, N., Marcus, G.A., Guarente, L. Mol. Cell. Biol. (1995)
- Characterization of mutations in NOT2 indicates that it plays an important role in maintaining the integrity of the CCR4-NOT complex. Russell, P., Benson, J.D., Denis, C.L. J. Mol. Biol. (2002)
- A targeted histone acetyltransferase can create a sizable region of hyperacetylated chromatin and counteract the propagation of transcriptionally silent chromatin. Chiu, Y.H., Yu, Q., Sandmeier, J.J., Bi, X. Genetics (2003)
- Multiple mechanistically distinct functions of SAGA at the PHO5 promoter. Barbaric, S., Reinke, H., Hörz, W. Mol. Cell. Biol. (2003)
- Identification of native complexes containing the yeast coactivator/repressor proteins NGG1/ADA3 and ADA2. Saleh, A., Lang, V., Cook, R., Brandl, C.J. J. Biol. Chem. (1997)
- Roles for Gcn5p and Ada2p in transcription and nucleotide excision repair at the Saccharomyces cerevisiae MET16 gene. Ferreiro, J.A., Powell, N.G., Karabetsou, N., Mellor, J., Waters, R. Nucleic Acids Res. (2006)
- Structure/functional properties of the yeast dual regulator protein NGG1 that are required for glucose repression. Brandl, C.J., Martens, J.A., Margaliot, A., Stenning, D., Furlanetto, A.M., Saleh, A., Hamilton, K.S., Genereaux, J. J. Biol. Chem. (1996)
- The acidic transcriptional activation domains of herpes virus VP16 and yeast HAP4 have different co-factor requirements. Wang, L., Turcotte, B., Guarente, L., Berger, S.L. Gene (1995)