Gene Review:
ADR1 - Adr1p
Saccharomyces cerevisiae S288c
Synonyms:
Regulatory protein ADR1, YD8142.16, YD8142B.08, YDR216W
- Transcriptional control of the yeast acetyl-CoA synthetase gene, ACS1, by the positive regulators CAT8 and ADR1 and the pleiotropic repressor UME6. Kratzer, S., Schüller, H.J. Mol. Microbiol. (1997)
- DNABIND: an interactive microcomputer program searching for nucleotide sequences that may code for conserved DNA-binding protein motifs. Mrázek, J., Kypr, J. Comput. Appl. Biosci. (1992)
- Cyclic AMP-dependent protein kinase phosphorylates and inactivates the yeast transcriptional activator ADR1. Cherry, J.R., Johnson, T.R., Dollard, C., Shuster, J.R., Denis, C.L. Cell (1989)
- Transcription factor IIIA induced bending of the Xenopus somatic 5S gene promoter. Schroth, G.P., Cook, G.R., Bradbury, E.M., Gottesfeld, J.M. Nature (1989)
- Two zinc fingers of a yeast regulatory protein shown by genetic evidence to be essential for its function. Blumberg, H., Eisen, A., Sledziewski, A., Bader, D., Young, E.T. Nature (1987)
- Sequence homology of the yeast regulatory protein ADR1 with Xenopus transcription factor TFIIIA. Hartshorne, T.A., Blumberg, H., Young, E.T. Nature (1986)
- The Saccharomyces cerevisiae ADR1 gene is a positive regulator of transcription of genes encoding peroxisomal proteins. Simon, M., Adam, G., Rapatz, W., Spevak, W., Ruis, H. Mol. Cell. Biol. (1991)
- Characterization of a p53-related activation domain in Adr1p that is sufficient for ADR1-dependent gene expression. Young, E.T., Saario, J., Kacherovsky, N., Chao, A., Sloan, J.S., Dombek, K.M. J. Biol. Chem. (1998)
- Multiple pathways are co-regulated by the protein kinase Snf1 and the transcription factors Adr1 and Cat8. Young, E.T., Dombek, K.M., Tachibana, C., Ideker, T. J. Biol. Chem. (2003)
- A C-terminal region of the Saccharomyces cerevisiae transcription factor ADR1 plays an important role in the regulation of peroxisome proliferation by fatty acids. Simon, M.M., Pavlik, P., Hartig, A., Binder, M., Ruis, H., Cook, W.J., Denis, C.L., Schanz, B. Mol. Gen. Genet. (1995)
- Alanine scanning site-directed mutagenesis of the zinc fingers of transcription factor ADR1: residues that contact DNA and that transactivate. Thukral, S.K., Morrison, M.L., Young, E.T. Proc. Natl. Acad. Sci. U.S.A. (1991)
- ADH2 expression is repressed by REG1 independently of mutations that alter the phosphorylation of the yeast transcription factor ADR1. Dombek, K.M., Camier, S., Young, E.T. Mol. Cell. Biol. (1993)
- Overexpression of the yeast transcriptional activator ADR1 induces mutation of the mitochondrial genome. Cherry, J.R., Denis, C.L. Curr. Genet. (1989)
- Adr1 and Cat8 synergistically activate the glucose-regulated alcohol dehydrogenase gene ADH2 of the yeast Saccharomyces cerevisiae. Walther, K., Schüller, H.J. Microbiology (Reading, Engl.) (2001)
- Expression of GUT1, which encodes glycerol kinase in Saccharomyces cerevisiae, is controlled by the positive regulators Adr1p, Ino2p and Ino4p and the negative regulator Opi1p in a carbon source-dependent fashion. Grauslund, M., Lopes, J.M., Rønnow, B. Nucleic Acids Res. (1999)
- Identification of functional regions in the yeast transcriptional activator ADR1. Bemis, L.T., Denis, C.L. Mol. Cell. Biol. (1988)
- ADR1-mediated transcriptional activation requires the presence of an intact TFIID complex. Komarnitsky, P.B., Klebanow, E.R., Weil, P.A., Denis, C.L. Mol. Cell. Biol. (1998)
- Isolation and characterization of further cis- and trans-acting regulatory elements involved in the synthesis of glucose-repressible alcohol dehydrogenase (ADHII) in Saccharomyces cerevisiae. Ciriacy, M. Mol. Gen. Genet. (1979)
- Saccharomyces cerevisiae PIP2 mediating oleic acid induction and peroxisome proliferation is regulated by Adr1p and Pip2p-Oaf1p. Rottensteiner, H., Wabnegger, L., Erdmann, R., Hamilton, B., Ruis, H., Hartig, A., Gurvitz, A. J. Biol. Chem. (2003)
- ADR1 activation domains contact the histone acetyltransferase GCN5 and the core transcriptional factor TFIIB. Chiang, Y.C., Komarnitsky, P., Chase, D., Denis, C.L. J. Biol. Chem. (1996)
- Dissection of the ADR1 protein reveals multiple, functionally redundant activation domains interspersed with inhibitory regions: evidence for a repressor binding to the ADR1c region. Cook, W.J., Chase, D., Audino, D.C., Denis, C.L. Mol. Cell. Biol. (1994)
- Isolation and characterization of the positive regulatory gene ADR1 from Saccharomyces cerevisiae. Denis, C.L., Young, E.T. Mol. Cell. Biol. (1983)
- Isoform-specific purification and substrate specificity of the 5'-AMP-activated protein kinase. Michell, B.J., Stapleton, D., Mitchelhill, K.I., House, C.M., Katsis, F., Witters, L.A., Kemp, B.E. J. Biol. Chem. (1996)
- Mechanism of DNA binding by the ADR1 zinc finger transcription factor as determined by SPR. Schaufler, L.E., Klevit, R.E. J. Mol. Biol. (2003)
- Designing zinc-finger ADR1 mutants with altered specificity of DNA binding to T in UAS1 sequences. Taylor, W.E., Suruki, H.K., Lin, A.H., Naraghi-Arani, P., Igarashi, R.Y., Younessian, M., Katkus, P., Vo, N.V. Biochemistry (1995)